Zobrazeno 1 - 10
of 378
pro vyhledávání: '"Francesco Di Virgilio"'
Autor:
Ylenia Longo, Sara Moreno Mascaraque, Giuseppe Andreacchio, Julia Werner, Ichiro Katahira, Elena De Marchi, Anna Pegoraro, Robert Jan Lebbink, Karl Köhrer, Patrick Petzsch, Ronny Tao, Francesco Di Virgilio, Elena Adinolfi, Ingo Drexler
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionModified Vaccinia Virus Ankara (MVA) is a safe vaccine vector inducing long- lasting and potent immune responses. MVA-mediated CD8+T cell responses are optimally induced, if both, direct- and cross-presentation of viral or recombinant ant
Externí odkaz:
https://doaj.org/article/c51d0799a12d4c9e9a19762506b18869
Autor:
Maria Pina Notarangelo, Letizia Penolazzi, Elisabetta Lambertini, Simonetta Falzoni, Pasquale De Bonis, Cristina Capanni, Francesco Di Virgilio, Roberta Piva
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
A comprehensive understanding of the molecules that play key roles in the physiological and pathological homeostasis of the human intervertebral disc (IVD) remains challenging, as does the development of new therapeutic treatments. We recently found
Externí odkaz:
https://doaj.org/article/9535fd74f6e64ed9908505704d26553a
Autor:
Alejandro Sánchez Melgar, Valentina Vultaggio-Poma, José Luis Albasanz, Francesco Di Virgilio, Mairena Martín
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S256- (2023)
Externí odkaz:
https://doaj.org/article/c0736958b65f47e2ae927adb89c4e4a3
Autor:
Maximilian Wilmes, Carolina Pinto Espinoza, Peter Ludewig, Joschi Stabernack, Arthur Liesz, Annette Nicke, Mathias Gelderblom, Christian Gerloff, Simonetta Falzoni, Eva Tolosa, Francesco Di Virgilio, Björn Rissiek, Nikolaus Plesnilla, Friedrich Koch-Nolte, Tim Magnus
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Previous studies have demonstrated that purinergic receptors could be therapeutic targets to modulate the inflammatory response in multiple models of brain diseases. However, tools for the selective and efficient targeting of thes
Externí odkaz:
https://doaj.org/article/42a72dde94804cbaafa23cc1ebad1ef5
Autor:
Valentina Vultaggio-Poma, Juana Maria Sanz, Andrea Amico, Alessandra Violi, Sara Ghisellini, Stefano Pizzicotti, Angelina Passaro, Alberto Papi, Marco Libanore, Francesco Di Virgilio, Anna Lisa Giuliani
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe pathophysiology of the Corona Virus Disease 2019 (COVID-19) is incompletely known. A robust inflammatory response caused by viral replication is a main cause of the acute lung and multiorgan injury observed in critical patients. Infla
Externí odkaz:
https://doaj.org/article/7ef4c0fc0d244266aee856923d94c4f3
Autor:
Letizia Penolazzi, Maria Pina Notarangelo, Elisabetta Lambertini, Valentina Vultaggio-Poma, Mario Tarantini, Francesco Di Virgilio, Roberta Piva
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Identifying the subcellular localization of a protein within a cell is often an essential step in understanding its function. The main objective of this report was to determine the presence of the P2X7 receptor (P2X7R) in healthy human cells of skele
Externí odkaz:
https://doaj.org/article/f79fdcc835944e4bbe1dbc00e0d8efb0
Autor:
Michele Zanoni, Alba Clara Sarti, Alice Zamagni, Michela Cortesi, Sara Pignatta, Chiara Arienti, Michela Tebaldi, Anna Sarnelli, Antonino Romeo, Daniela Bartolini, Luigino Tosatto, Elena Adinolfi, Anna Tesei, Francesco Di Virgilio
Publikováno v:
Cell Death and Disease, Vol 13, Iss 1, Pp 1-14 (2022)
Abstract Glioblastoma (GBM) is the most lethal brain tumor in adults. Radiation, together with temozolomide is the standard treatment, but nevertheless, relapse occurs in nearly all cases. Understanding the mechanisms underlying radiation resistance
Externí odkaz:
https://doaj.org/article/93eda6c223714969ac1cbd1eb4ba8691
Autor:
Carla Enrica Gallenga, Martina Maritati, Marco Mura, Francesco Di Virgilio, Pio Conti, Carlo Contini
Publikováno v:
Microorganisms, Vol 11, Iss 9, p 2198 (2023)
Among the symptoms of SARS-CoV-2, follicular conjunctivitis has become relevant. The conjunctiva acts as an open lymph node, reacting to the viral antigen that binds the epithelial cells, forming follicles of B cells with activated T cells and NK cel
Externí odkaz:
https://doaj.org/article/a8c37614388a4650bb24f35093670804
Autor:
Anna Pegoraro, Elena De Marchi, Manuela Ferracin, Elisa Orioli, Michele Zanoni, Cristian Bassi, Anna Tesei, Marina Capece, Emi Dika, Massimo Negrini, Francesco Di Virgilio, Elena Adinolfi
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-12 (2021)
Abstract Tumor growth and metastatic spreading are heavily affected by the P2X7 receptor as well as microvesicles and exosomes release into the tumor microenvironment. P2X7 receptor stimulation is known to trigger vesicular release from immune and ce
Externí odkaz:
https://doaj.org/article/47d92cf271a542258cc92c6596ad9022
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9465 (2023)
The discovery of the P2X7 receptor (P2X7R, originally named P2Z) in immune cells, its cloning, and the identification of its role in a multiplicity of immune-mediated diseases raised great hopes for the development of novel and more potent anti-infla
Externí odkaz:
https://doaj.org/article/20c2420eac7a462fbb67c70dd1dfc7fe