Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Francesco Demetrio, Lofaro"'
Autor:
Francesco Demetrio Lofaro, Sonia Costa, Maria Luisa Simone, Daniela Quaglino, Federica Boraldi
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Pseudoxanthoma elasticum (PXE) is a rare disease characterized by ectopic calcification, however, despite the widely spread effect of pro/anti-calcifying systemic factors associated with this genetic metabolic condition, it is not known why
Externí odkaz:
https://doaj.org/article/f7c38f3a7b784ba98e239f047aa3b3d4
Autor:
Federica Boraldi, Francesco Demetrio Lofaro, Susanna Bonacorsi, Alessia Mazzilli, Maria Garcia-Fernandez, Daniela Quaglino
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1586 (2024)
Fibroblasts are typical mesenchymal cells widely distributed throughout the human body where they (1) synthesise and maintain the extracellular matrix, ensuring the structural role of soft connective tissues; (2) secrete cytokines and growth factors;
Externí odkaz:
https://doaj.org/article/22232f7541b54423a6b2ce11c437e42f
Autor:
Barbara Cisterna, Francesco Demetrio Lofaro, Maria Assunta Lacavalla, Federico Boschi, Manuela Malatesta, Daniela Quaglino, Carlo Zancanaro, Federica Boraldi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: A regular physical training is known to contribute to preserve muscle mass and strength, maintaining structure and function of neural and vascular compartments and preventing muscle insulin resistance and inflammation. However, physical
Externí odkaz:
https://doaj.org/article/c9353c6beb434055848574ccbe83d2c6
Autor:
Giada Zanini, Valentina Selleri, Milena Nasi, Anna De Gaetano, Ilaria Martinelli, Giulia Gianferrari, Francesco Demetrio Lofaro, Federica Boraldi, Jessica Mandrioli, Marcello Pinti
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11881 (2022)
Amyotrophic lateral sclerosis is the most common form of motor neuron disease. Mutations in TARDBP, the gene encoding the RNA-binding protein TDP-43, are responsible for about 5% of familial ALS. Here we report the clinical and biological features of
Externí odkaz:
https://doaj.org/article/ab50c09eb8c84a1da9266487ff88bc66
Autor:
Francesco Demetrio Lofaro, Dario Pasquale Mucciolo, Vittoria Murro, Laura Pavese, Daniela Quaglino, Federica Boraldi
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Pseudoxanthoma elasticum (PXE) is a rare autosomal recessive disease clinically characterised by early cutaneous alterations, and by late clinically relevant ocular, and cardiovascular manifestations. ABCC6 genetic tests are used to confirm clinical
Externí odkaz:
https://doaj.org/article/46dedb352f6e4c0c98ae2146bcfddaa5
Autor:
Francesco Demetrio Lofaro, Federica Boraldi, Maria Garcia-Fernandez, Lara Estrella, Pedro Valdivielso, Daniela Quaglino
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Pseudoxanthoma elasticum (PXE) is a genetic disease considered as a paradigm of ectopic mineralization disorders, being characterized by multisystem clinical manifestations due to progressive calcification of skin, eyes, and the cardiovascular system
Externí odkaz:
https://doaj.org/article/77c8979edf6b4958870b651785307f45
Autor:
Federica Boraldi, Francesco Demetrio Lofaro, Sonia Costa, Pasquale Moscarelli, Daniela Quaglino
Publikováno v:
Frontiers in Medicine, Vol 6 (2020)
A number of beta-thalassemia patients, independently from the type of beta-thalassemia (β0 or β+) and blood transfusion requirements, may develop, after puberty, dermal, cardiovascular, and ocular complications associated with an ectopic mineraliza
Externí odkaz:
https://doaj.org/article/558843d690884941bb155a002f20c73e
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1559 (2022)
Elastin represents the structural component of the extracellular matrix providing elastic recoil to tissues such as skin, blood vessels and lungs. Elastogenic cells secrete soluble tropoelastin monomers into the extracellular space where these monome
Externí odkaz:
https://doaj.org/article/43ced9ebf2ee4c83b4d0021ea5268ee9
Autor:
Federica Boraldi, Francesco Demetrio Lofaro, Giulia Bergamini, Agnese Ferrari, Davide Malagoli
Publikováno v:
Biology, Vol 10, Iss 10, p 1049 (2021)
Pomacea canaliculata is a freshwater gastropod known for being both a highly invasive species and one of the possible intermediate hosts of the mammalian parasite Angiostrongylus cantonensis. With the aim of providing new information concerning P. ca
Externí odkaz:
https://doaj.org/article/5761d35be9174abcbe97e7269938ec39
Autor:
Francesco Demetrio Lofaro, Barbara Cisterna, Maria Assunta Lacavalla, Federico Boschi, Manuela Malatesta, Daniela Quaglino, Carlo Zancanaro, Federica Boraldi
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10564 (2021)
Aging is characterized by a progressive decline of skeletal muscle (SM) mass and strength which may lead to sarcopenia in older persons. To date, a limited number of studies have been performed in the old SM looking at the whole, complex network of t
Externí odkaz:
https://doaj.org/article/2fda4a34841543abbb561cba27606d8f