Zobrazeno 1 - 10
of 381
pro vyhledávání: '"Francesco Dazzi"'
Autor:
Daniele Avenoso, Fabio Serpenti, Liron Barnea Slonim, Styliani Bouziana, Francesco Dazzi, Guy Hannah, Michelle Kenyon, Varun Mehra, Austin Kulasekararaj, Pramila Krishnamurthy, Mili Naresh Shah, Sharon Lionel, Antonio Pagliuca, Victoria Potter
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 16, Iss 1 (2024)
Background: Allogeneic haematopoietic stem-cell transplant is a potentially curative option for high-risk acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS) patients. Post-transplant cyclophosphamide administration allows for selection
Externí odkaz:
https://doaj.org/article/909489ad418c407599dc7b384cd7f4ba
Autor:
Sandhya Moise, Luigi Dolcetti, Francesco Dazzi, Paul Roach, Lee Buttery, Sheila MacNeil, Nick Medcalf
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 50, Iss 1, Pp 168-176 (2022)
Mesenchymal stromal cells (MSCs) show immunosuppressive effects both via cell-to-cell contact (direct) with immune cells and by producing paracrine factors and extracellular vesicles (indirect). A key challenge in delivering this therapeutic effect i
Externí odkaz:
https://doaj.org/article/553c2c08f92940b3af31d4ab98942208
Autor:
Fabio Serpenti, Daniele Avenoso, Kenyon Michelle, Pramila Krishnamurthy, Varun Mehra, Austin Kulasekararaj, Shreyans Gandhi, Francesco Dazzi, Shah Mili Naresh, Ye Ting Leung, Sandra Anteh, Madson Correia de Farias, Styliani Bouziana, Christianne Bourlon, Oana Diana Dragoi, Tony Pagliuca, Victoria Potter
Publikováno v:
HemaSphere, Vol 7, p e22273e7 (2023)
Externí odkaz:
https://doaj.org/article/8ba754c875d34bf9b4cbd73e6b96dfcc
Autor:
Daniele Avenoso, Amal Alabdulwahab, Michelle Kenyon, Varun Mehra, Pramila Krishnamurthy, Francesco Dazzi, Ye Ting Leung, Sandra Anteh, Mili Naresh Shah, Andrea Kuhnl, Robin Sanderson, Piers Patten, Deborah Yallop, Antonio Pagliuca, Victoria Potter
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 15, Iss 1 (2023)
Background: The second decade of this millennium was characterized by a widespread availability of chimeric antigen receptor T-cell (CAR-T)therapies to treat relapsed and refractory lymphomas. As expected, the role and indication of allogeneic hae
Externí odkaz:
https://doaj.org/article/3ba90f4479c343d691aa52b2eb923b7c
Autor:
Gaia Alberti, Corinne Arsuffi, Alice Pievani, Domenico Salerno, Francesco Mantegazza, Francesco Dazzi, Andrea Biondi, Sarah Tettamanti, Marta Serafini
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In acute myeloid leukemia (AML), malignant stem cells hijack the normal bone marrow niche where they are largely protected from the current therapeutic approaches. Thus, eradicating these progenitors is the ultimate challenge in the treatment of this
Externí odkaz:
https://doaj.org/article/693cec58a41b476bba4843a54cfe5697
Autor:
Vipul Sheth, Victoria Potter, Hugues de Lavallade, Shreyans Gandhi, Austin Kulasekararaj, Pramila Krishnamurthy, Varun Mehra, Francesco Dazzi, Ghulam Mufti, Antonio Pagliuca, Donal Mclornan, Kavita Raj
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 7, Pp 1-6 (2021)
Abstract Pre-emptive DLI (pDLI) is an effective strategy in lowering the risk of relapse without significantly increasing the risk of graft-versus-host disease (GVHD) in the case of T cell lineage mixed chimerism (MC) post allogeneic transplant in he
Externí odkaz:
https://doaj.org/article/6a6208a955b94bbda77e11e80c805e95
Autor:
Silvia A. Ferreira, Meghna S. Motwani, Peter A. Faull, Alexis J. Seymour, Tracy T. L. Yu, Marjan Enayati, Dheraj K. Taheem, Christoph Salzlechner, Tabasom Haghighi, Ewa M. Kania, Oommen P. Oommen, Tarek Ahmed, Sandra Loaiza, Katarzyna Parzych, Francesco Dazzi, Oommen P. Varghese, Frederic Festy, Agamemnon E. Grigoriadis, Holger W. Auner, Ambrosius P. Snijders, Laurent Bozec, Eileen Gentleman
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
3D hydrogels have provided information on the physical requirements of stem cell fate, but the contribution of interactions with the pericellular environment are under-explored. Here the authors show that pericellular matrix secreted by human bone ma
Externí odkaz:
https://doaj.org/article/8af8d8a81ddc405d9f52c6d4512ee247
Autor:
Luise Müller, Antje Tunger, Manja Wobus, Malte von Bonin, Russell Towers, Martin Bornhäuser, Francesco Dazzi, Rebekka Wehner, Marc Schmitz
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mesenchymal stromal cells (MSCs) are characterized by an extraordinary capacity to modulate the phenotype and functional properties of various immune cells that play an essential role in the pathogenesis of inflammatory disorders. Thus, MSCs efficien
Externí odkaz:
https://doaj.org/article/1e1d2d3802e6401c9a6a73cd97374963
Autor:
Marco Romano, Raul Elgueta, Daniel McCluskey, Ana Maria Ortega-Prieto, Emilie Stolarczyk, Francesco Dazzi, Baltasar Lucendo-Villarin, Jose Meseguer-Ripolles, James Williams, Giorgia Fanelli, David C. Hay, Fiona M. Watt, Giovanna Lombardi
Publikováno v:
Cells, Vol 11, Iss 1, p 24 (2021)
Regenerative medicine aims to replace damaged tissues by stimulating endogenous tissue repair or by transplanting autologous or allogeneic cells. Due to their capacity to produce unlimited numbers of cells of a given cell type, pluripotent stem cells
Externí odkaz:
https://doaj.org/article/4bc8b73c5c6f4a5aadacfd862fdb872e
Autor:
Tik Shing Cheung, Giuliana Minani Bertolino, Chiara Giacomini, Martin Bornhäuser, Francesco Dazzi, Antonio Galleu
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The immunosuppressive activity of mesenchymal stromal cells (MSCs) in graft versus host disease (GvHD) is well-documented, but their therapeutic benefit is rather unpredictable. Prospective randomized clinical trials remain the only means to address
Externí odkaz:
https://doaj.org/article/7285e8577afd49409d7815f303b6382f