Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Francesco Cogo"'
Autor:
Aidan P. McCann, Peter Smyth, Francesco Cogo, William J. McDaid, Lai Jiang, Jia Lin, Emma Evergren, Roberta E. Burden, Sandra Van Schaeybroeck, Christopher J. Scott, James F. Burrows
Publikováno v:
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-12 (2018)
Abstract Background The deubiquitinase USP17 is overexpressed in NSCLC and has been shown to be required for the growth and motility of EGFR wild-type (WT) NSCLC cells. USP17 is also required for clathrin-mediated endocytosis of EGFR. Here, we examin
Externí odkaz:
https://doaj.org/article/389459c8bc77420cac6802a897ba1482
Autor:
Laura Girardi, Matteo Figliuzzi, Maurizio Poli, Munevver Serdarogullari, Cristina Patassini, Silvia Caroselli, Ilaria Pergher, Francesco Cogo, Onder Coban, Fazilet Kubra Boynukalin, Mustafa Bahceci, Roser Navarro, Carmen Rubio, Necati Findikli, Carlos Simón, Antonio Capalbo
Publikováno v:
Human Reproduction. 38:982-991
STUDY QUESTION How well can whole chromosome copy number analysis from a single trophectoderm (TE) biopsy predict true mosaicism configurations in human blastocysts? SUMMARY ANSWER When a single TE biopsy is tested, wide mosaicism thresholds (i.e. 20
Publikováno v:
Current Opinion in Obstetrics & Gynecology. 33:178-183
Purpose of review Expanded Carrier Screening (ECS) is a genetic test able to detect carriers for a large number of autosomal recessive and X-linked diseases. Its clinical utilization is increasing but some technical aspects for its implementation are
Publikováno v:
Biochimie. 166
Proteases are hydrolytic enzymes fundamental for a variety of physiological processes, but the loss of their regulation leads to aberrant functions that promote onset and progression of many diseases including cancer. Proteases have been implicated i
Autor:
Roberta E. Burden, Wioletta Rut, Richard Williams, Christopher J. Scott, Katarzyna Groborz, Marcin Drag, Marcin Poreba, Daniel B. Longley, Peter Smyth, Michael C. Johnston, Guy S. Salvesen, Francesco Cogo
Publikováno v:
Nanoscale
Cogo, F, Smyth, P, Burden, R, Longley, D B, Williams, R, Johnston, M, Poreba, M, Rut, W, Groborz, K, Salvesen, G, Drag, M & Scott, C J 2018, ' Development of an advanced nanoformulation for the intracellular delivery of a caspase-3 selective activity-based probe ', Nanoscale-Royal Society of Chemistry . https://doi.org/10.1039/C8NR07859A
Cogo, F, Smyth, P, Burden, R, Longley, D B, Williams, R, Johnston, M, Poreba, M, Rut, W, Groborz, K, Salvesen, G, Drag, M & Scott, C J 2018, ' Development of an advanced nanoformulation for the intracellular delivery of a caspase-3 selective activity-based probe ', Nanoscale-Royal Society of Chemistry . https://doi.org/10.1039/C8NR07859A
The ability to label active caspase-3 represents a useful pharmacodynamic strategy to determine the efficacy of anti-tumour drugs. Activity-based probes (ABPs) provide a method for the labelling of activated caspases and the recent development of hyb
Autor:
Christopher J. Scott, Michelle K. Greene, Donna M. Small, Peter Smyth, Francesco Cogo, José A. Bengoechea, Aidan P. McCann, Joana Sa Pessoa, Clifford C. Taggart, José Luis Insua, Lai Jiang
Publikováno v:
Jiang, L, Greene, M K, Insua, J L, Sa-Pessoa, J, Small, D M, Smyth, P, McCann, A, Cogo, F, Bengoechea, J A, Taggart, C C & Scott, C J 2018, ' Clearance of intracellular Klebsiella pneumoniae infection using gentamicin-loaded nanoparticles ', Journal of Controlled Release, vol. 279, pp. 316 . https://doi.org/10.1016/j.jconrel.2018.04.040
Klebsiella pneumoniae is a foremost gram-negative pathogen that can induce life-threatening nosocomial pulmonary infections. Although it can be phagocytosed successfully by lung resident macrophages, this pathogen remains viable within vacuolar compa