Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Francesco Buonfiglio"'
Publikováno v:
Antioxidants, Vol 13, Iss 10, p 1249 (2024)
Cataracts, a leading cause of blindness worldwide, are closely linked to oxidative stress-induced damage to lens epithelial cells (LECs). Key factors contributing to cataract formation include aging, arterial hypertension, and diabetes mellitus. Give
Externí odkaz:
https://doaj.org/article/07bcdd6581594c689b7b33ea7645a1c7
Autor:
Elsa Wilma Böhm, Francesco Buonfiglio, Anna Maria Voigt, Philipp Bachmann, Tarek Safi, Norbert Pfeiffer, Adrian Gericke
Publikováno v:
Redox Biology, Vol 68, Iss , Pp 102967- (2023)
Oxidative stress occurs through an imbalance between the generation of reactive oxygen species (ROS) and the antioxidant defense mechanisms of cells. The eye is particularly exposed to oxidative stress because of its permanent exposure to light and d
Externí odkaz:
https://doaj.org/article/077894b5c88c4284b21e0b57d122a648
Autor:
Adrian Gericke, Francesco Buonfiglio
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 5, p 190 (2024)
Nitric oxide synthases (NOS) are essential regulators of vascular function, and their role in ocular blood vessels is of paramount importance for maintaining ocular homeostasis. Three isoforms of NOS—endothelial (eNOS), neuronal (nNOS), and inducib
Externí odkaz:
https://doaj.org/article/5073c3b930e645ca9e9fb206e7b0eec3
Autor:
Qi Tang, Francesco Buonfiglio, Elsa Wilma Böhm, Liyu Zhang, Norbert Pfeiffer, Christina A. Korb, Adrian Gericke
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 594 (2024)
Diabetic retinopathy (DR) represents a severe complication of diabetes mellitus, characterized by irreversible visual impairment resulting from microvascular abnormalities. Since the global prevalence of diabetes continues to escalate, DR has emerged
Externí odkaz:
https://doaj.org/article/b978fbb9580347408f43ab7ac41793fa
Autor:
Verena Prokosch, Sarah B. Zwingelberg, Desislava V. Efremova, Francesco Buonfiglio, Norbert Pfeiffer, Adrian Gericke
Publikováno v:
Diseases, Vol 12, Iss 5, p 92 (2024)
Purpose: To investigate whether trabecular aspiration (TA) has an effective medium-term intraocular pressure (IOP)-lowering and medication-saving effect in patients with pseudoexfoliation glaucoma (PEG). In addition, a subgroup analysis of patients w
Externí odkaz:
https://doaj.org/article/fb1c1ad7cb294be8a49ff8d3d9ebc663
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 817 (2024)
Acknowledged as a significant pathogenetic driver for numerous diseases, aging has become a focal point in addressing the profound changes associated with increasing human life expectancy, posing a critical concern for global public health. Emerging
Externí odkaz:
https://doaj.org/article/82691c89e9d64a35a3ea0ce297d5dc03
Publikováno v:
Antioxidants, Vol 13, Iss 2, p 148 (2024)
Retinopathy of prematurity (ROP) is a proliferative vascular ailment affecting the retina. It is the main risk factor for visual impairment and blindness in infants and young children worldwide. If left undiagnosed and untreated, it can progress to r
Externí odkaz:
https://doaj.org/article/28588b0edd314554b943d75f4f192088
Publikováno v:
Antioxidants, Vol 13, Iss 1, p 120 (2024)
Diabetes mellitus, the most prevalent endocrine disorder, not only impacts the retina but also significantly involves the ocular surface. Diabetes contributes to the development of dry eye disease and induces morphological and functional corneal alte
Externí odkaz:
https://doaj.org/article/e9c3cd065e664832a66bb50bd98e6bf7
Autor:
Francesco Buonfiglio, Ning Xia, Can Yüksel, Caroline Manicam, Subao Jiang, Jenia Kouchek Zadeh, Aytan Musayeva, Eva Elksne, Norbert Pfeiffer, Andreas Patzak, Huige Li, Adrian Gericke
Publikováno v:
Diseases, Vol 11, Iss 4, p 124 (2023)
Atherogenic lipoproteins may impair vascular reactivity, leading to tissue damage in various organs, including the eye. This study aimed to investigate whether ophthalmic artery reactivity is affected in mice lacking the apolipoprotein E gene (ApoE
Externí odkaz:
https://doaj.org/article/1cfb0c37382d4bf09e614c9a206c61f0
Publikováno v:
Pharmaceuticals, Vol 16, Iss 9, p 1193 (2023)
Glaucoma, a group of diseases characterized by progressive retinal ganglion cell loss, cupping of the optic disc, and a typical pattern of visual field defects, is a leading cause of severe visual impairment and blindness worldwide. Elevated intraocu
Externí odkaz:
https://doaj.org/article/e48eb95beae64be3ba02ad893849773e