Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Francesco Baschieri"'
Autor:
Alice Nordlinger, Justine Del Rio, Shivang Parikh, Laetitia Thomas, Roma Parikh, Hananya Vaknine, Ronen Brenner, Francesco Baschieri, Aude Robert, Mehdi Khaled
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Metastases are the major cause of cancer-related death, yet, molecular weaknesses that could be exploited to prevent tumor cells spreading are poorly known. Here, we found that perturbing hydrolase transport to lysosomes by blocking either t
Externí odkaz:
https://doaj.org/article/12beb77ff9994d4da5b03472ebf3ed64
Autor:
Santosh Phuyal, Francesco Baschieri
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Mechanical stimuli have profound effects on the cellular architecture and functions. Over the past two decades, considerable progress has been made in unraveling the molecular machineries that confer cells the ability to sense and transduce mechanica
Externí odkaz:
https://doaj.org/article/872bef1523624617bc3365c2336eb6c9
Autor:
Francesco Baschieri, Stéphane Dayot, Nadia Elkhatib, Nathalie Ly, Anahi Capmany, Kristine Schauer, Timo Betz, Danijela Matic Vignjevic, Renaud Poincloux, Guillaume Montagnac
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Cells sense mechanical properties of their environment using various cellular structures including focal adhesions. Here, the authors identify flat clathrin-coated structures (CCSs) as mechanosensitive signaling platforms that form independently of c
Externí odkaz:
https://doaj.org/article/7c868a476ff541acbb2290819e5e83b7
Autor:
Alexander Kyumurkov, Anne-Pascale Bouin, Mathieu Boissan, Sandra Manet, Francesco Baschieri, Mathilde Proponnet-Guerault, Martial Balland, Olivier Destaing, Myriam Régent-Kloeckner, Claire Calmel, Alice Nicolas, François Waharte, Philippe Chavrier, Guillaume Montagnac, Emmanuelle Planus, Corinne Albiges-Rizo
Publikováno v:
Journal of Cell Biology
Journal of Cell Biology, 2023, 222 (1), ⟨10.1083/jcb.202004025⟩
Journal of Cell Biology, Rockefeller University Press, 2023, 222 (1), ⟨10.1083/jcb.202004025⟩
Journal of Cell Biology, 2023, 222 (1), ⟨10.1083/jcb.202004025⟩
Journal of Cell Biology, Rockefeller University Press, 2023, 222 (1), ⟨10.1083/jcb.202004025⟩
International audience; Integrin endocytosis is essential for many fundamental cellular processes. Whether and how the internalization impacts cellular mechanics remains elusive. Whereas previous studies reported the contribution of the integrin acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe61a3b2c47dad1962707fc3ffa2406
https://hal.science/hal-03834328/file/jcb_202004025.pdf
https://hal.science/hal-03834328/file/jcb_202004025.pdf
Autor:
Francesco Baschieri, Abigail Illand, Jorge Barbazan, Olivier Zajac, Clémence Henon, Damarys Loew, Florent Dingli, Danijela Matic Vignjevic, Sandrine Lévêque-Fort, Guillaume Montagnac
Fibroblasts play a fundamental role in tumor development. Among other functions, they regulate cancer cells migration through rearranging the extracellular matrix, secreting soluble factors and establishing direct physical contacts with cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3800224649a697e6c45bb63f1e7a610
https://doi.org/10.1101/2022.09.06.506801
https://doi.org/10.1101/2022.09.06.506801
Autor:
Camille Hauguel, Sarah Ducellier, Olivier Provot, Nada Ibrahim, Diana Lamaa, Coline Balcerowiak, Boris Letribot, Megane Nascimento, Vincent Blanchard, Laurie Askenatzis, Helene Levaique, Jérôme Bignon, Francesco Baschieri, Cyril Bauvais, Guillaume Bollot, Dolor Renko, Alain Deroussent, Bastien Prost, Marie-Catherine Laisne, Sophie Michallet, Laurence Lafanechère, Sébastien Papot, Guillaume Montagnac, Christine Tran, Mouad Alami, Sebastien Apcher, Abdallah Hamze
Publikováno v:
European Journal of Medicinal Chemistry. 240:114573
A series of quinoline and quinazoline analogs were designed and synthesized as new tubulin polymerization (TP) and histone deacetylases (HDAC) inhibitors. Compounds 12a and 12d showed the best cytotoxicity activities against a panel of human cancer c
Autor:
Gitta Maria Seleznik, Rossella Parrotta, Sabrina Sonda, Paola Martinelli, Amedeo Caflisch, Francesco Baschieri, Rolf Graf, Irene Esposito, Michele Visentin, Marta Bombardo, Ermanno Malagola, Johanna Buschmann, Hesso Farhan, Rong Chen, Nathalie Borgeaud, Enrica Saponara
Publikováno v:
The Journal of Pathology. 246:352-365
Pancreatic ductal adenocarcinoma (PDAC), the primary cause of pancreatic cancer mortality, is poorly responsive to currently available interventions. Identifying new targets that drive PDAC formation and progression is critical to develop alternative
Publikováno v:
Journal of Cell Science. 133
Clathrin-mediated endocytosis is the main entry route for most cell surface receptors and their ligands. It is regulated by clathrin-coated structures that are endowed with the ability to cluster receptors and to locally bend the plasma membrane, res
Autor:
Samuel Tettarasar, Francesco Baschieri, Nadia Elkhatib, Dahiana Le Devedec, Guillaume Montagnac
Publikováno v:
Journal of Cell Science.
Cells experience mechanical stresses in different physiological and pathological settings. Clathrin-coated structures (CCSs) are sensitive to such perturbations in a way that often results in a mechanical impairment of endocytic budding. Compressive
Cells experience mechanical stresses in different physiological and pathological settings. Clathrin-coated structures (CCSs) are sensitive to such perturbations in a way that often results in a mechanical impairment of their capacity to bud, ultimate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a02eb3d50224800a26aea29edb0c1e
https://doi.org/10.1101/2019.12.19.883066
https://doi.org/10.1101/2019.12.19.883066