Combining predominant polarity and affective spectrum concepts in bipolar disorder: towards a novel theoretical and clinical perspective

Autor: Francesco Bartoli, Gin S. Malhi, Giuseppe Carrà

Publikováno v: International Journal of Bipolar Disorders, Vol 12, Iss 1, Pp 1-9 (2024)

Abstract This is an overview of recent advances on predominant polarity conceptualization in bipolar disorder (BD). Current evidence on its operationalized definitions, possible contextualization within the affective spectrum, along with its epidemio

Externí odkaz: https://doaj.org/article/e573ca2c5731471e9337d3762dd597f5

Prevalence and correlates of manic/hypomanic and depressive predominant polarity in bipolar disorder: systematic review and meta-analysis

Autor: Francesco Bartoli, Carlo Bassetti, Marco Gazzola, Letizia Gianfelice, Daniele Cavaleri, Cristina Crocamo, Giuseppe Carrà

Publikováno v: BJPsych Open, Vol 10 (2024)

Background Identification of the predominant polarity, i.e. hypomanic/manic (mPP) or depressive predominant polarity (dPP), might help clinicians to improve personalised management of bipolar disorder. Aims We performed a systematic review and meta-

Externí odkaz: https://doaj.org/article/f953e39c1d7a4c48b89d50f47aa44873

Tolerability of vortioxetine compared to selective serotonin reuptake inhibitors in older adults with major depressive disorder (VESPA): a randomised, assessor-blinded and statistician-blinded, multicentre, superiority trialResearch in context

Autor: Giovanni Ostuzzi, Chiara Gastaldon, Mauro Tettamanti, Massimo Cartabia, Igor Monti, Andrea Aguglia, Eugenio Aguglia, Francesco Bartoli, Camilla Callegari, Andrea Canozzi, Elvira Anna Carbone, Giuseppe Carrà, Rosangela Caruso, Simone Cavallotti, Stefania Chiappini, Fabrizio Colasante, Beatrice Compri, Armando D'Agostino, Pasquale De Fazio, Renato de Filippis, Matteo Gari, Marta Ielmini, Gianmarco Ingrosso, Silvia Mammarella, Giovanni Martinotti, Alessandro Rodolico, Rita Roncone, Enrico Sterzi, Lorenzo Tarsitani, Elisa Tiberto, Liliana Todini, Francesco Amaddeo, Barbara D'Avanzo, Angelo Barbato, Corrado Barbui, Maria Chiara Alessi, Gabriele Avincola, Bianca Bachi, Gianna Bernasconi, Andrea Birgillito, Emanuele Bisso, Stefano Bonora, Angela Calabrese, Tommaso Callovini, Aurelia Canestro, Salvo Canonico, Chiara Alessandro Capogrosso, Elvira Carbone, Doriana Carosielli, Ivano Caselli, Daniele Cavaleri, Clara Cavallotto, Marco Cesca, Cecilia Chiarenza, Riccardo Matteo Cioni, Sara Coloccini, Marco Cruciata, Claudia Cumerlato, Renato De Filippis, Manuela De Palma, Sasha Del Vecchio, Bianca Della Rocca, Chiara Di Natale, Ettore D'Onofrio, Irene Espa, Giulia Fior, Marta Gancitano, Barbara Giordano, Laura Giusti, Luigi Grassi, Pierluca Guzzi, Celeste Isella, Annamaria Lax, Leonardo Marano, Federico Marconi, Marco Marella, Alessia Metelli, Giulia Michencig, Andrea Miuli, Alessandro Moncada, Pietro Morello, Federico Moretti, Marco Morreale, Alessio Mosca, Christian Nasti, Michela Nosé, Filippo Ogheri, Margherita Oresti, Alessandra Ornaghi, Dario Palpella, Corinna Pancheri, Davide Papola, Silvia Passeri, Mauro Pettorusso, Susanna Piacenti, Irene Pinucci, Valentina Pugliese, Marianna Purgato, Marianna Rania, Federica Robbi, Samantha Romito, Barbara Ronchi, Valentina Roselli, Cristina Segura-Garcia, Maria Salvina Signorelli, Gabriele Simonelli, Antonella Sociali, Serena Sturiale, Antonio Tambelli, Beatrice Todesco, Alice Trabucco, Giulia Turrini, Veronica Villa, Federico Wiedenmann, Luca Zambuto, Elisa Zanini, Chiara Zannini, Luigi Zerbinati

Publikováno v: EClinicalMedicine, Vol 69, Iss , Pp 102491- (2024)

Summary: Background: Major depressive disorder (MDD) is prevalent and disabling among older adults. Standing on its tolerability profile, vortioxetine might be a promising alternative to selective serotonin reuptake inhibitors (SSRIs) in such a vulne

Externí odkaz: https://doaj.org/article/b6d9532a29514d6885cce2880822f39b

Off–label long acting injectable antipsychotics in real–world clinical practice: a cross-sectional analysis of prescriptive patterns from the STAR Network DEPOT study

Autor: Armando D’Agostino, Andrea Aguglia, Corrado Barbui, Francesco Bartoli, Giuseppe Carrà, Simone Cavallotti, Margherita Chirico, Edoardo G. Ostinelli, Caroline Zangani, Giovanni Martinotti, Giovanni Ostuzzi, STAR Network Depot Investigators

Publikováno v: BMC Psychiatry, Vol 22, Iss 1, Pp 1-9 (2022)

Abstract Introduction Information on the off–label use of Long–Acting Injectable (LAI) antipsychotics in the real world is lacking. In this study, we aimed to identify the sociodemographic and clinical features of patients treated with on– vs o

Externí odkaz: https://doaj.org/article/f46be87402654b9d91cfbca44ac8a80a

Tumor Progression from a Fibroblast Activation Protein Perspective: Novel Diagnostic and Therapeutic Scenarios for Colorectal Cancer

Autor: Martina Rossetti, Stefano Stanca, Rossella Del Frate, Francesco Bartoli, Andrea Marciano, Enrica Esposito, Alessandra Fantoni, Anna Paola Erba, Piero Vincenzo Lippolis, Pinuccia Faviana

Publikováno v: Diagnostics, Vol 13, Iss 20, p 3199 (2023)

In 2020, the Global Cancer Observatory estimated the incidence of colorectal cancer (CRC) at around 10.7% coupled with a mortality rate of 9.5%. The explanation for these values lies in the tumor microenvironment consisting of the extracellular matri

Externí odkaz: https://doaj.org/article/dc4e1c01f64f4dadbe052ee9dbea2845