Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Francesco, Zonta"'
Autor:
Francesco Zonta, Sergio Pantano
Publikováno v:
Mechanobiology in Medicine, Vol 2, Iss 3, Pp 100083- (2024)
Interactions between macromolecules orchestrate many mechanobiology processes. However, progress in the field has often been hindered by the monetary and time costs of obtaining reliable experimental structures. In recent years, deep-learning methods
Externí odkaz:
https://doaj.org/article/69416ba409494f62b71c35d8abce0cab
Autor:
Chiara Peres, Caterina Sellitto, Chiara Nardin, Sabrina Putti, Tiziana Orsini, Chiara Di Pietro, Daniela Marazziti, Adriana Vitiello, Arianna Calistri, Mara Rigamonti, Ferdinando Scavizzi, Marcello Raspa, Francesco Zonta, Guang Yang, Thomas W. White, Fabio Mammano
Publikováno v:
EBioMedicine, Vol 89, Iss , Pp 104453- (2023)
Summary: Background: Keratitis ichthyosis deafness (KID) syndrome is a rare disorder caused by hemichannel (HC) activating gain-of-function mutations in the GJB2 gene encoding connexin (Cx) 26, for which there is no cure, or current treatments based
Externí odkaz:
https://doaj.org/article/bd169d1992394aeab17af27a91b30026
Autor:
Mojgan Ghodrati-Misek, Thomas Schlöglhofer, Christoph Gross, Alexander Maurer, Daniel Zimpfer, Dietrich Beitzke, Francesco Zonta, Francesco Moscato, Heinrich Schima, Philipp Aigner
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Atrial fibrillation (AF) is a common comorbidity in left ventricular assist device (LVAD) patients and has been identified as a risk factor for thromboembolic stroke. Blood stagnation within the left atrial appendage (LAA) is considered a possible ma
Externí odkaz:
https://doaj.org/article/b82586eb946040bfa81fb6a5c950ec88
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1595-1602 (2021)
Poly glutamine and glutamine-rich peptides play a central role in a plethora of pathological aggregation events. However, biophysical characterization of soluble oligomers -the most toxic species involved in these processes- remains elusive due to th
Externí odkaz:
https://doaj.org/article/ec5ced50bc0f49d5bb16de881b3bc3e7
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
SARS-CoV-2 infects humans and causes Coronavirus disease 2019 (COVID-19). The S1 domain of the spike glycoprotein of SARS-CoV-2 binds to human angiotensin-converting enzyme 2 (hACE2) via its receptor-binding domain, while the S2 domain facilitates fu
Externí odkaz:
https://doaj.org/article/af8050795abc45a8b32ffeecb46773d2
Autor:
Bianca Calì, Andrielly H. R. Agnellini, Chiara Cioccarelli, Ricardo Sanchez-Rodriguez, Andrea Predonzani, Giulia Ilaria Toffolo, Antonella Viola, Vincenzo Bronte, Giorgio Arrigoni, Francesco Zonta, Laura Albertoni, Claudia Mescoli, Ilaria Marigo, Barbara Molon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Reactive oxygen species, including RNS, contribute to the control of multiple immune cell functions within the tumor microenvironment (TME). Tumor-infiltrating myeloid cells (TIMs) represent the archetype of tolerogenic cells that actively contribute
Externí odkaz:
https://doaj.org/article/176364a6d24742f3a8c5d201ad2fd5ec
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1285 (2022)
The steady increase in computational power in the last 50 years is opening unprecedented opportunities in biology, as computer simulations of biological systems have become more accessible and can reproduce experimental results more accurately. Here,
Externí odkaz:
https://doaj.org/article/1f7384aa3c224219a7d33021dd218cc3
Publikováno v:
Data in Brief, Vol 36, Iss , Pp 107109- (2021)
This dataset contains a collection of molecular dynamics (MD) simulations of polyglutamine (polyQ) and glutamine-rich (Q-rich) peptides in the multi-microsecond timescale. Primary data from coarse-grained simulations performed using the SIRAH force f
Externí odkaz:
https://doaj.org/article/e1afdb4cca2b490bb703d646ae0c4436
Autor:
Mattia Vicario, Ginevra Zanni, Francesca Vallese, Filippo Santorelli, Alessandro Grinzato, Domenico Cieri, Paola Berto, Martina Frizzarin, Raffaele Lopreiato, Francesco Zonta, Stefania Ferro, Michele Sandre, Oriano Marin, Maria Ruzzene, Enrico Bertini, Giuseppe Zanotti, Marisa Brini, Tito Calì, Ernesto Carafoli
Publikováno v:
Neurobiology of Disease, Vol 115, Iss , Pp 157-166 (2018)
The fine regulation of intracellular calcium is fundamental for all eukaryotic cells. In neurons, Ca2+ oscillations govern the synaptic development, the release of neurotransmitters and the expression of several genes. Alterations of Ca2+ homeostasis
Externí odkaz:
https://doaj.org/article/e150d2b6b39046888fbd11d8fd4b98bd
Autor:
Zhiwei Song, Francesco Zonta, Lucas León Peralta Ogorek, Viggo Klint Bastegaard, Max Herzog, Elisa Pellegrini, Ole Pedersen
Publikováno v:
Song, Z, Zonta, F, Peralta Ogorek, L L, Bastegaard, V K, Herzog, M, Pellegrini, E & Pedersen, O 2023, ' The quantitative importance of key root traits for radial water loss under low water potential ', Plant and Soil, vol. 482 . https://doi.org/10.1007/s11104-022-05711-y
Aims Root tissue water can be lost to the dry topsoil via radial water loss (RWL) resulting in root shrinking and loss of contact with the rhizosphere. The root barrier to radial oxygen loss (ROL) has been shown to restrict RWL, therefore we hypothes