Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Francesco, Tramutola"'
Autor:
Rocchina Miglionico, Paolo Lupattelli, Luigi Milella, Faustino Bisaccia, Maria Funicello, Federico Berti, Francesco Tramutola, Maria Francesca Armentano, Lucia Chiummiento, Rosarita D'Orsi
Publikováno v:
Bioorganicmedicinal chemistry. 27(9)
New heteroaryl HIV-protease inhibitors bearing a carbamoyl spacer were synthesized in few steps and high yield, from commercially available homochiral epoxides. Different substitution patterns were introduced onto a given isopropanoyl-sulfonamide cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d86bbf1feb21fcaf44096907fb95690d
https://pubmed.ncbi.nlm.nih.gov/30922618
https://pubmed.ncbi.nlm.nih.gov/30922618
Autor:
Paolo Lupattelli, Lucia Chiummiento, Vittoria Infantino, Vito Iacobazzi, Paolo Convertini, Francesco Tramutola
Publikováno v:
Chemico-Biological Interactions. 237:1-8
Anigopreissin A belongs to stilbene di- and oligomeric forms containing a benzofuran ring system whose biological activity is unknown. Recently, a completely protected Anigopreissin A - Permethylated Anigopreissin A - has been synthesized. We use MTT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e66b5ea37f9e6839291de6ff44ff162
https://doi.org/10.1016/j.cbi.2015.05.005
https://doi.org/10.1016/j.cbi.2015.05.005
Publikováno v:
Synthetic Communications. 45:1799-1806
A method for C-Br/C-H bis-phenylation of methyl 4-bromocrotonate via nickel-catalyzed cross-coupling reaction has been developed. This protocol involves commercially available catalyst components and furnishes a suitable doubly phenylated building bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a71b5a2b0ed5abf431dff3cbbca385dd
https://doi.org/10.1080/00397911.2015.1049274
https://doi.org/10.1080/00397911.2015.1049274
Autor:
Federico Berti, Carlo Bonini, Francesco Tramutola, Paolo Lupattelli, Rocco Pandolfo, Margherita De Bonis, Maria Funicello, Lucia Chiummiento, Nadia Di Blasio
Publikováno v:
Journal of Medicinal Chemistry. 53:1451-1457
A series of new thienyl ring containing analogues of nelfinavir and saquinavir with different substitution patterns were synthesized from suitable enantiopure diols. Their inhibitory activity against wild type recombinant HIV-1 protease was evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd2ce0e349495eccc56bd188b348908
https://doi.org/10.1021/jm900846f
https://doi.org/10.1021/jm900846f
Autor:
Luigi Milella, Maria Funicello, Federico Berti, Fabio Benedetti, Paolo Lupattelli, Faustino Bisaccia, Francesco Tramutola, Lucia Chiummiento, Maria Francesca Armentano, Rocchina Miglionico
Publikováno v:
Bioorganicmedicinal chemistry. 25(17)
New heteroaryl HIV-protease inhibitors bearing a carboxyamide spacer were synthesized in few steps and high yield, from commercially available homochiral epoxides. Different substitution patterns were introduced onto a given isopropanoyl-sulfonamide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326da42d4da5a038d396085be4ca5e95
https://pubmed.ncbi.nlm.nih.gov/28739156
https://pubmed.ncbi.nlm.nih.gov/28739156
Publikováno v:
Organic Letters. 14:3928-3931
An effective ligand-free Suzuki coupling protocol to unite methyl (E)-4-bromobut-2-enoate with several arylboronic acids has been accomplished. Thus, a number of variously functionalized methyl 4-arylcrotonates have been achieved in high to excellent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29cb8c01e0af11e5a94871ba0027014f
https://doi.org/10.1021/ol3016786
https://doi.org/10.1021/ol3016786
Publikováno v:
Chirality. 24:345-348
A simple high-yield three-steps route to optically active 4-hydroxymethyl-3-(1H-indolyl)oxazolidin-2-ones from (S)-glycidol is described. The key intermediates (R)-oxiran-2-ylmethyl 1H-indol-4/-5-ylcarbamates are obtained in high yields from (S)-glyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed3f2558199bab7cbf1f5cd6908dcaf
https://doi.org/10.1002/chir.22003
https://doi.org/10.1002/chir.22003
Publikováno v:
Tetrahedron. 65:5984-5989
A series of non-peptidic HIV protease inhibitors were synthesized starting from the same optically active precursor, (S)-glycidol. The substrate was easily converted into different indolic sulfonamides or amines by regioselective reactions. The preli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fd7f9136c5f7a5cceccedf25eae43a
https://doi.org/10.1016/j.tet.2009.05.089
https://doi.org/10.1016/j.tet.2009.05.089
Autor:
Natascia Gliubizzi, Daniela Tofani, Antonella Marmo, Francesco Tramutola, Lucia Chiummiento, Maria Funicello, Paolo Lupattelli
Publikováno v:
ChemInform. 46
Amberlyst 15 was an efficient and green catalyst for the reaction of 2,3-diaryloxiranes with H 2 O in organic co-solvent to prepare glycols in high yield. Ortho substituted trans 2,3-diaryloxiranes afforded the corresponding syn glycols stereo- and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::500a34a62ed1e83e0c83de78f24671c0
https://doi.org/10.1002/chin.201547105
https://doi.org/10.1002/chin.201547105