Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Francesco, Petrelli"'
Autor:
Kelly Ceyzériat, Aurélien M. Badina, Francesco Petrelli, Sylvie Montessuit, Alekos Nicolaides, Philippe Millet, Armand Savioz, Jean-Claude Martinou, Benjamin B. Tournier
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106623- (2024)
Alzheimer's Disease (AD) is characterized by an accumulation of pathologic amyloid-beta (Aβ) and Tau proteins, neuroinflammation, metabolic changes and neuronal death. Reactive astrocytes participate in these pathophysiological processes by releasin
Externí odkaz:
https://doaj.org/article/39d3b21019b74feda4d780d17948f6b9
Autor:
Federico Miozzo, Eva P. Valencia-Alarcón, Luca Stickley, Michaëla Majcin Dorcikova, Francesco Petrelli, Damla Tas, Nicolas Loncle, Irina Nikonenko, Peter Bou Dib, Emi Nagoshi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Mitochondrial dysfunction in dopaminergic neurons is a pathological hallmark of Parkinson’s disease. Here, the authors find a conserved mechanism by which a single transcription factor controls mitochondrial health in dopaminergic neurons during th
Externí odkaz:
https://doaj.org/article/5f787c1c5eac4589a8bc26327c5c282e
Autor:
Francesco Petrelli, Tamara Zehnder, Anthony Laugeray, Sarah Mondoloni, Corrado Calì, Luca Pucci, Alicia Molinero Perez, Bianca Maria Bondiolotti, Eva De Oliveira Figueiredo, Glenn Dallerac, Nicole Déglon, Bruno Giros, Lorenzo Magrassi, Jean-Pierre Mothet, Manuel Mameli, Linda D. Simmler, Paola Bezzi
Publikováno v:
Biological Psychiatry. 93:966-975
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d83b0f768b791ca7291bd7acb71cbe
https://doi.org/10.1016/j.biopsych.2022.11.018
https://doi.org/10.1016/j.biopsych.2022.11.018
Autor:
Tamara Zehnder, Francesco Petrelli, Jennifer Romanos, Eva C. De Oliveira Figueiredo, Tommy L. Lewis, Jr., Nicole Déglon, Franck Polleux, Mirko Santello, Paola Bezzi
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108952- (2021)
Summary: The mechanisms controlling the post-natal maturation of astrocytes play a crucial role in ensuring correct synaptogenesis. We show that mitochondrial biogenesis in developing astrocytes is necessary for coordinating post-natal astrocyte matu
Externí odkaz:
https://doaj.org/article/f1df3debacce4887983091ca5960c352
Autor:
Diana Amantea, Francesco Petrelli, Rosaria Greco, Cristina Tassorelli, Maria Tiziana Corasaniti, Paolo Tonin, Giacinto Bagetta
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Repurposing existing drugs represents a promising approach for successful development of acute stroke therapies. In this context, the macrolide antibiotic azithromycin has been shown to exert neuroprotection in mice due to its immunomodulatory proper
Externí odkaz:
https://doaj.org/article/5fb0381633dc4339804394efd3faf421
Publikováno v:
Glia. 70:1585-1604
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eefc6850dfbb78302e4820dc26957e0
https://doi.org/10.1002/glia.24221
https://doi.org/10.1002/glia.24221
Publikováno v:
Biomolecules, Vol 10, Iss 7, p 1068 (2020)
Pyruvate, the end product of glycolysis, plays a major role in cell metabolism. Produced in the cytosol, it is oxidized in the mitochondria where it fuels the citric acid cycle and boosts oxidative phosphorylation. Its sole entry point into mitochond
Externí odkaz:
https://doaj.org/article/414dc3df84dc4a2da76a608ef0d04198
Autor:
Francesco Petrelli, Valentina Scandella, Sylvie Montessuit, Nicola Zamboni, Jean-Claude Martinou, Marlen Knobloch
Publikováno v:
Science advances, vol. 9, no. 9, pp. eadd5220
Science Advances, 9 (9)
Science Advances, 9 (9)
Cellular metabolism is important for adult neural stem/progenitor cell (NSPC) behavior. However, its role in the transition from quiescence to proliferation is not fully understood. We here show that the mitochondrial pyruvate carrier (MPC) plays a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3becfe1ace3f27980b5980b21de8ca1
https://doi.org/10.1101/2022.05.31.494137
https://doi.org/10.1101/2022.05.31.494137
Publikováno v:
Current opinion in lipidology, vol. 33, no. 1, pp. 86-87
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffba317db54a2232a085dbea1e786cdd
https://serval.unil.ch/notice/serval:BIB_5757AD2B8195
https://serval.unil.ch/notice/serval:BIB_5757AD2B8195
Autor:
Bianca Maria Bondiolotti, P. Bezzi, Nicole Déglon, Alicia Molinero Perez, Luca Pucci, Corrado Calì, Francesco Petrelli, Jean-Pierre Mothet, Tamara Zehnder, Glenn Dallérac, Lorenzo Magrassi, Bruno Giros, Fulvio Magara, Linda D. Simmler
Astrocytes control synaptic activity by modulating peri-synaptic concentrations of ion and neurotransmitters including dopamine and, as such, can be critically involved in the modulation of some aspect of mammalian behavior. Here we report that genet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b39536dfa82d09a1d1e850400c824eb
https://hal.science/hal-03438361
https://hal.science/hal-03438361