Zobrazeno 1 - 10 of 42 pro vyhledávání: '"Francesco, Matrisciano"'
1
Altered Expression and In Vivo Activity of mGlu5 Variant a Receptors in the Striatum of BTBR Mice: Novel Insights Into the Pathophysiology of Adult Idiopathic Forms of Autism Spectrum Disorders
Autor: Francesco, Matrisciano, Valentina, Locci, Erbo, Dong, Ferdinando, Nicoletti, Alessandro, Guidotti, Dennis R, Grayson
Publikováno v: Current Neuropharmacology. 20:2354-2368
Background: mGlu5 metabotropic glutamate receptors are considered as candidate drug targets in the treatment of “monogenic” forms of autism spectrum disorders (ASD), such as Fragile- X syndrome (FXS). However, despite promising preclinical data,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2808b03a658690a18dd768714b2d3f8d
https://doi.org/10.2174/1567202619999220209112609
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2
Akademický článek
PPAR and functional foods: Rationale for natural neurosteroid-based interventions for postpartum depression
Autor: Francesco Matrisciano, Graziano Pinna
Publikováno v: Neurobiology of Stress, Vol 12, Iss , Pp - (2020)
Allopregnanolone, a GABAergic neurosteroid and progesterone derivative, was recently approved by the Food and Drug Administration for the treatment of postpartum depression (PPD). Several mechanisms appear to be involved in the pathogenesis of PPD, i
Externí odkaz: https://doaj.org/article/539d4fbfba7b424aa1c3282515528110
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3
Akademický článek
PPAR-α Hypermethylation in the Hippocampus of Mice Exposed to Social Isolation Stress Is Associated with Enhanced Neuroinflammation and Aggressive Behavior
Autor: Francesco Matrisciano, Graziano Pinna
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 19, p 10678 (2021)
Social behavioral changes, including social isolation or loneliness, increase the risk for stress-related disorders, such as major depressive disorder, posttraumatic stress disorder (PTSD), and suicide, which share a strong neuroinflammatory etiopath
Externí odkaz: https://doaj.org/article/3b601ebeb98d4e3bbb3b2b4f0f78ad2b
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4
Akademický článek
Targeting mGlu Receptors for Optimization of Antipsychotic Activity and Disease-Modifying Effect in Schizophrenia
Autor: Ferdinando Nicoletti, Rosamaria Orlando, Luisa Di Menna, Milena Cannella, Serena Notartomaso, Giada Mascio, Luisa Iacovelli, Francesco Matrisciano, Francesco Fazio, Filippo Caraci, Agata Copani, Giuseppe Battaglia, Valeria Bruno
Publikováno v: Frontiers in Psychiatry, Vol 10 (2019)
Metabotropic glutamate (mGlu) receptors are considered as candidate drug targets for the treatment of schizophrenia. These receptors form a family of eight subtypes (mGlu1 to −8), of which mGlu1 and −5 are coupled to Gq/11, and all other subtypes
Externí odkaz: https://doaj.org/article/eddb1179ddd9452ba4c5009f897c51ef
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5
Functional Nutrition as Integrated Intervention for In- and Outpatient with Schizophrenia
Autor: Francesco Matrisciano
Publikováno v: Current Neuropharmacology. 21
Abstract: Schizophrenia is a chronic and progressive disorder characterized by cognitive, emotional,and behavioral abnormalities associated with neuronal development and synaptic plasticity alterations. Genetic and epigenetic abnormalities in cortica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::214ccd9eedceaf3d047526b1f4112251
https://doi.org/10.2174/1570159x21666230322160259
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7
Akademický článek
Epigenetic Alterations in Prenatal Stress Mice as an Endophenotype Model for Schizophrenia: Role of Metabotropic Glutamate 2/3 Receptors
Autor: Francesco Matrisciano, Erbo Dong, Ferdinando Nicoletti, Alessandro Guidotti
Publikováno v: Frontiers in Molecular Neuroscience, Vol 11 (2018)
Mice subjected to prenatal restraint stress (PRS mice) showed biochemical and behavioral abnormalities consistent with a schizophrenia-like phenotype (Matrisciano et al., 2016). PRS mice are characterized by increased DNA-methyltransferase 1 (DNMT1)
Externí odkaz: https://doaj.org/article/cee11fa7ba64430ba9b9d9a6e3f2aec9
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8
PPAR-α Hypermethylation in the Hippocampus of Mice Exposed to Social Isolation Stress Is Associated with Enhanced Neuroinflammation and Aggressive Behavior
Autor: Graziano Pinna, Francesco Matrisciano
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 10678, p 10678 (2021)
Volume 22
Issue 19
Social behavioral changes, including social isolation or loneliness, increase the risk for stress-related disorders, such as major depressive disorder, posttraumatic stress disorder (PTSD), and suicide, which share a strong neuroinflammatory etiopath
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0bb1bb5e744a62d35694c9e92ea14f
http://europepmc.org/articles/PMC8509148
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9
The allosteric dopamine D1 receptor potentiator, DETQ, ameliorates subchronic phencyclidine-induced object recognition memory deficits and enhances cortical acetylcholine efflux in male humanized D1 receptor knock-in mice
Autor: Junliang Hao, Francesco Matrisciano, Kjell A. Svensson, Lakshmi Rajagopal, Herbert Y. Meltzer, Mei Huang
Publikováno v: Behavioural Brain Research. 361:139-150
Diminished dopamine D1 stimulation may contribute to cognitive impairment in Alzheimer's and Parkinson's diseases, schizophrenia, and other neuropsychiatric disorders. However, orthosteric D1 receptor (D1R) agonists produce receptor desensitization a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80414d225c9a9bc450633780bf7f652d
https://doi.org/10.1016/j.bbr.2018.12.006
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10
Elektronická kniha
Epigenetic Functional Nutrition: When Science Meets the Table
Autor: Francesco Matrisciano Hood, Author
Bioactive compounds such as polyphenols, bioflavonoids, and phytonutrients exert antioxidants, anti-inflammatory and anticancer activities that might support and protect our organism in fighting against inflammatory-based chronic diseases.This book c
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