Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Francesco, Marampon"'
Autor:
Matteo Cassandri, Antonella Porrazzo, Silvia Pomella, Beatrice Noce, Clemens Zwergel, Francesca Antonella Aiello, Francesca Vulcano, Luisa Milazzo, Simona Camero, Deborah Pajalunga, Massimo Spada, Valeria Manzi, Giovanni Luca Gravina, Silvia Codenotti, Michela Piccione, Miriam Tomaciello, Michele Signore, Giovanni Barillari, Cinzia Marchese, Alessandro Fanzani, Biagio De Angelis, Concetta Quintarelli, Christopher R. Vakoc, Eleanor Y. Chen, Francesca Megiorni, Franco Locatelli, Sergio Valente, Antonello Mai, Rossella Rota, Francesco Marampon
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-20 (2024)
Abstract Radiotherapy (RT) plays a critical role in the management of rhabdomyosarcoma (RMS), the prevalent soft tissue sarcoma in childhood. The high risk PAX3-FOXO1 fusion-positive subtype (FP-RMS) is often resistant to RT. We have recently demonst
Externí odkaz:
https://doaj.org/article/d2578a217b0d469480a398078bb622c7
Autor:
Simona Camero, Luisa Milazzo, Francesca Vulcano, Federica Ceccarelli, Paola Pontecorvi, Francesca Pedini, Alessandra Rossetti, Elena Sofia Scialis, Giulia Gerini, Fabrizio Cece, Silvia Pomella, Matteo Cassandri, Antonella Porrazzo, Enrico Romano, Claudio Festuccia, Giovanni Luca Gravina, Simona Ceccarelli, Rossella Rota, Lavinia Vittoria Lotti, Fabio Midulla, Antonio Angeloni, Cinzia Marchese, Francesco Marampon, Francesca Megiorni
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-24 (2024)
Abstract Background Despite a multimodal approach including surgery, chemo- and radiotherapy, the 5-year event-free survival rate for rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in childhood, remains very poor for metastatic patients,
Externí odkaz:
https://doaj.org/article/0b81896720af4a4a9845e88f03e04c18
Autor:
Silvia Pomella, Matteo Cassandri, Lucrezia D’Archivio, Antonella Porrazzo, Cristina Cossetti, Doris Phelps, Clara Perrone, Michele Pezzella, Antonella Cardinale, Marco Wachtel, Sara Aloisi, David Milewski, Marta Colletti, Prethish Sreenivas, Zoë S. Walters, Giovanni Barillari, Angela Di Giannatale, Giuseppe Maria Milano, Cristiano De Stefanis, Rita Alaggio, Sonia Rodriguez-Rodriguez, Nadia Carlesso, Christopher R. Vakoc, Enrico Velardi, Beat W. Schafer, Ernesto Guccione, Susanne A. Gatz, Ajla Wasti, Marielle Yohe, Myron Ignatius, Concetta Quintarelli, Janet Shipley, Lucio Miele, Javed Khan, Peter J. Houghton, Francesco Marampon, Berkley E. Gryder, Biagio De Angelis, Franco Locatelli, Rossella Rota
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Rhabdomyosarcomas (RMS) are pediatric mesenchymal-derived malignancies encompassing PAX3/7-FOXO1 Fusion Positive (FP)-RMS, and Fusion Negative (FN)-RMS with frequent RAS pathway mutations. RMS express the master myogenic transcription factor
Externí odkaz:
https://doaj.org/article/b02d638fdabc4c31acb1630b1acf4c96
Autor:
Irene Fasciani, Francesco Petragnano, Ziming Wang, Ruairidh Edwards, Narasimha Telugu, Ilaria Pietrantoni, Ulrike Zabel, Henrik Zauber, Marlies Grieben, Maria E Terzenidou, Jacopo Di Gregorio, Cristina Pellegrini, Silvano Santini, Anna R Taddei, Bärbel Pohl, Stefano Aringhieri, Marco Carli, Gabriella Aloisi, Francesco Marampon, Eve Charlesworth, Alexandra Roman, Sebastian Diecke, Vincenzo Flati, Franco Giorgi, Fernanda Amicarelli, Andrew B Tobin, Marco Scarselli, Kostas Tokatlidis, Mario Rossi, Martin J Lohse, Paolo Annibale, Roberto Maggio
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002582 (2024)
Muscarinic acetylcholine receptors are prototypical G protein-coupled receptors (GPCRs), members of a large family of 7 transmembrane receptors mediating a wide variety of extracellular signals. We show here, in cultured cells and in a murine model,
Externí odkaz:
https://doaj.org/article/55337ca4f8c84555b649a08804c2bd5c
Autor:
Paolo Tini, Francesco Marampon, Martina Giraffa, Samira Bucelli, Maximilian Niyazi, Claus Belka, Giuseppe Minniti
Publikováno v:
Radiation Oncology, Vol 18, Iss 1, Pp 1-8 (2023)
Abstract Background The management of brain metastases (BM), the major cause of cancer morbidity and mortality, is becoming an emerging area of interest. Surgery, whole brain radiation therapy (WBRT), or stereotactic radiosurgery (SRS), have historic
Externí odkaz:
https://doaj.org/article/da1ad9ebaa0040dda4cbe86a258a2114
Autor:
Clara Perrone, Silvia Pomella, Matteo Cassandri, Michele Pezzella, Stefano Giuliani, Tecla Gasperi, Antonella Porrazzo, Anna Alisi, Anna Pastore, Silvia Codenotti, Alessandro Fanzani, Giovanni Barillari, Libenzio Adrian Conti, Biagio De Angelis, Concetta Quintarelli, Paolo Mariottini, Franco Locatelli, Francesco Marampon, Rossella Rota, Manuela Cervelli
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Rhabdomyosarcoma (RMS) is a pediatric myogenic soft tissue sarcoma that includes fusion-positive (FP) and fusion-negative (FN) molecular subtypes. FP-RMS expresses PAX3-FOXO1 fusion protein and often shows dismal prognosis. FN-RMS shows cytogenetic a
Externí odkaz:
https://doaj.org/article/ef551ba1bce14ec79854aa47d12b0851
Autor:
Sara Vaccaro, Alessandra Rossetti, Antonella Porrazzo, Simona Camero, Matteo Cassandri, Silvia Pomella, Miriam Tomaciello, Giampiero Macioce, Francesca Pedini, Giovanni Barillari, Cinzia Marchese, Rossella Rota, Giovanni Cenci, Mario Tombolini, Robert A. Newman, Peiying Yang, Silvia Codenotti, Alessandro Fanzani, Francesca Megiorni, Claudio Festuccia, Giuseppe Minniti, Giovanni Luca Gravina, Francesca Vulcano, Luisa Milazzo, Francesco Marampon
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Treatment of rhabdomyosarcoma (RMS), the most common a soft tissue sarcoma in childhood, provides intensive multimodal therapy, with radiotherapy (RT) playing a critical role for local tumor control. However, since RMS efficiently activates mechanism
Externí odkaz:
https://doaj.org/article/35544f0854274470951c3529077bc1d1
Autor:
Simona Camero, Matteo Cassandri, Silvia Pomella, Luisa Milazzo, Francesca Vulcano, Antonella Porrazzo, Giovanni Barillari, Cinzia Marchese, Silvia Codenotti, Miriam Tomaciello, Rossella Rota, Alessandro Fanzani, Francesca Megiorni, Francesco Marampon
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Management of rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in children, frequently accounting the genitourinary tract is complex and requires a multimodal therapy. In particular, as a consequence of the advancement in dose conformity t
Externí odkaz:
https://doaj.org/article/6ae4c65046c24c3fbce7b1e3457a09c9
Autor:
Miriam Conte, Maria Silvia De Feo, Viviana Frantellizzi, Miriam Tomaciello, Francesco Marampon, Laura Evangelista, Luca Filippi, Giuseppe De Vincentis
Publikováno v:
Diagnostics, Vol 13, Iss 16, p 2628 (2023)
Background: Radio-guided surgery is a reliable approach used for localizing ground-glass opacities, lung nodules, and metastatic lymph nodes. Lung nodules, lymph node metastatic involvement, and ground-glass opacities often represent a challenge for
Externí odkaz:
https://doaj.org/article/f935c0e613484d5b979a316656d8c467
Autor:
Francesca De Felice, Valentina Lancellotta, Lisa Vicenzi, Sara Costantini, Alfredo Antonacci, Valentina Cerboneschi, Daniela Cristino, Luca Tagliaferri, Annamaria Cerrotta, Andrea Vavassori, Sergio Gribaudo, Alessandro Colombo, Francesco Lucà, Raffaele Barbara, Monica Mangoni, Francesco Marampon, Daniela Musio, Filippo Bellati, Ilary Ruscito, Francesco Torcia, Vincenzo Tombolini, Mattia Osti, Vitaliana De Sanctis
Publikováno v:
Journal of Contemporary Brachytherapy, Vol 13, Iss 2, Pp 231-243 (2021)
Externí odkaz:
https://doaj.org/article/19423d1a8cbd4d64895d8567c7126e1a