Development of Imidazole-Reactive Molecules Leading to a New Aggregation-Induced Emission Fluorophore Based on the Cinnamic Scaffold

Autor: Vincenzo Razzano, Marco Paolino, Annalisa Reale, Germano Giuliani, Roberto Artusi, Gianfranco Caselli, Michela Visintin, Francesco Makovec, Alessandro Donati, Francesca Villafiorita-Monteleone, Chiara Botta, Andrea Cappelli

Publikováno v: ACS Omega, Vol 2, Iss 9, Pp 5453-5459 (2017)

Externí odkaz: https://doaj.org/article/b8eea733b8cb4eb39a97d3536228eca9

Hyaluronan-Based Graft Copolymers Bearing Aggregation-Induced Emission Flurogens

Autor: Raniero Mendichi, Lorenzo Depau, Francesco Makovec, Marco Paolino, Giorgio Grisci, Claudia Bonechi, Vincenzo Razzano, Chiara Botta, Germano Giuliani, Mariano Licciardi, Filippo Samperi, Annalisa Reale, Alessandro Donati, Stefania Lamponi, Salvatore Battiato, Andrea Cappelli

Publikováno v: RSC advances 8 (2018): 5864–5881. doi:10.1039/c7ra12543g
info:cnr-pdr/source/autori:Cappelli, Andrea; Paolino, Marco; Reale, Annalisa; Razzano, Vincenzo; Grisci, Giorgio; Giuliani, Germano; Donati, Alessandro; Bonechi, Claudia; Lamponi, Stefania; Mendichi, Raniero; Battiato, Salvatore; Samperi, Filippo; Makovec, Francesco; Licciardi, Mariano; Depau, Lorenzo; Botta, Chiara/titolo:Hyaluronan-based graft copolymers bearing aggregation-induced emission fluorogens/doi:10.1039%2Fc7ra12543g/rivista:RSC advances/anno:2018/pagina_da:5864/pagina_a:5881/intervallo_pagine:5864–5881/volume:8

In order to develop a technology platform based on two natural compounds from biorenewable resources, a short series of hyaluronan (HA) copolymers grafted with propargylated ferulic acid (HA-FA-Pg) were designed and synthesized to show different graf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bac107489386ef065c84f607d33ec3cf
http://hdl.handle.net/10447/269880

Multivalent ligands for the serotonin 5-HT4 receptor† †Electronic supplementary information (ESI) available: Experimental details for the synthesis and characterization of target compounds and their intermediates. The experimental procedures used in the biological studies. See DOI: 10.1039/c6md00458j ‡ ‡The authors declare no competing interests

Autor: Federica, Castriconi, Marco, Paolino, Alessandro, Donati, Germano, Giuliani, Maurizio, Anzini, Laura, Mennuni, Chiara, Sabatini, Marco, Lanza, Gianfranco, Caselli, Francesco, Makovec, Maria, Sbraccia, Paola, Molinari, Tommaso, Costa, Andrea, Cappelli

Multivalency does not improve the binding and functional activities of ML10302 at 5-HT4 receptors.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f2cecbc39613f6395848f8ad2e85b7f9
https://europepmc.org/articles/PMC6071950/

Development of Imidazole-Reactive Molecules Leading to a New Aggregation-Induced Emission Fluorophore Based on the Cinnamic Scaffold

Autor: Francesca Villafiorita-Monteleone, Alessandro Donati, Gianfranco Caselli, Chiara Botta, Francesco Makovec, Michela Visintin, Annalisa Reale, Vincenzo Razzano, Andrea Cappelli, Germano Giuliani, Marco Paolino, Roberto Artusi

Publikováno v: ACS omega 2 (2017): 5453–5459. doi:10.1021/acsomega.7b00789
info:cnr-pdr/source/autori:V.Razzano, M. Paolino, A. Reale, G. Giuliani, R. Artusi, G. Caselli, M. Visintin, F. Makovec, A. Donati, F. Villafiorita-Monteleone, C. Botta, and A. Cappelli/titolo:Development of Imidazole-Reactive Molecules Leading to a New Aggregation-Induced Emission Fluorophore Based on the Cinnamic Scaffold/doi:10.1021%2Facsomega.7b00789/rivista:ACS omega/anno:2017/pagina_da:5453/pagina_a:5459/intervallo_pagine:5453–5459/volume:2
ACS Omega, Vol 2, Iss 9, Pp 5453-5459 (2017)
ACS Omega

In order to obtain new fluorophores potentially useful in imidazole labeling and subsequent conjugation, a small series of Morita- Baylis-Hillman acetates (3a-c) was designed, synthesized, and reacted with imidazole. The optical properties of the cor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418addc151cc34caa785a1f71daeaaa7
http://www.cnr.it/prodotto/i/380650

Design, Synthesis, and Preliminary Biological Evaluation of Pyrrolo[3,4-c]quinolin-1-one and Oxoisoindoline Derivatives as Aggrecanase Inhibitors

Autor: Salvatore Vomero, Gianluca Giorgi, Salvatore Valenti, Francesco Makovec, Antonio Giordani, Maurizio Anzini, Gianfranco Caselli, Luigi Piero Stasi, Germano Giuliani, Laura Mennuni, Andrea Cappelli, Chiara Nannicini

Publikováno v: ChemMedChem. 5:739-748

A small set of aggrecanase inhibitors based on the pyrrolo[3,4-c]quinolin-1-one or oxoisoindoline frameworks bearing a 4-(benzyloxy)phenyl substituent and different zinc binding groups were rationally designed and evaluated in silico by docking studi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617b402e3920592626cd378c85b05c92
https://doi.org/10.1002/cmdc.200900523