Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Francesco, Giorgianni"'
Autor:
Saini Setua, Shabia Shabir, Poornima Shaji, Ana Martinez Bulnes, Anupam Dhasmana, Swathi Holla, Nivesh K. Mittal, Nirakar Sahoo, Tripti Saini, Francesco Giorgianni, Mohammad Sikander, Andrew E. Massey, Bilal B. Hafeez, Manish K. Tripathi, Vincent P. Diego, Meena Jaggi, Junming Yue, Nadeem Zafar, Murali M. Yallapu, Stephen W. Behrman, Sheema Khan, Subhash C. Chauhan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 3009-3026 (2024)
The application of extracellular vesicles, particularly exosomes (EXs), is rapidly expanding in the field of medicine, owing to their remarkable properties as natural carriers of biological cargo. This study investigates utilization of exosomes deriv
Externí odkaz:
https://doaj.org/article/b13d607f6b544b0597ad67d93abf981c
Autor:
Pradeep K. Shukla, Roshan G. Rao, Avtar S. Meena, Francesco Giorgianni, Sue Chin Lee, Preeti Raju, Nitesh Shashikanth, Chandra Shekhar, Sarka Beranova, Louisa Balazs, Gabor Tigyi, Ankush Gosain, RadhaKrishna Rao
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe mechanism underlying radiation-induced gut microbiota dysbiosis is undefined. This study examined the effect of radiation on the intestinal Paneth cell α-defensin expression and its impact on microbiota composition and mucosal tissue
Externí odkaz:
https://doaj.org/article/2b2aefb595764eb3a340fbbf4f20d09e
Publikováno v:
Biochemistry and Biophysics Reports, Vol 32, Iss , Pp 101345- (2022)
Retinal pigment epithelium (RPE) are specialized multifunctional cells indispensable for maintenance of vision. Dysfunction and death of the RPE cells is implicated in the genesis and progression of age-related macular degeneration (AMD). Oxidative s
Externí odkaz:
https://doaj.org/article/0ec0c772647a4bbc87ea9365359b2dd9
Autor:
Avtar S. Meena, Pradeep K. Shukla, Briar Bell, Francesco Giorgianni, Rebeca Caires, Carlos Fernández-Peña, Sarka Beranova, Eitaro Aihara, Marshall H. Montrose, Mehdi Chaib, Liza Makowski, Indira Neeli, Marko Z. Radic, Valeria Vásquez, Jonathan H. Jaggar, Julio F. Cordero-Morales, RadhaKrishna Rao
Publikováno v:
Cell Reports, Vol 39, Iss 11, Pp 110937- (2022)
Summary: Intestinal epithelial tight junction disruption is a primary contributing factor in alcohol-associated endotoxemia, systemic inflammation, and multiple organ damage. Ethanol and acetaldehyde disrupt tight junctions by elevating intracellular
Externí odkaz:
https://doaj.org/article/e5f537285d734a398709ecbe67fe5d88
Autor:
Ylenia Ingrasciotta, Viviana Lacava, Ilaria Marcianò, Francesco Giorgianni, Giovanni Tripepi, Graziella D’ Arrigo, Alessandro Chinellato, Daniele Ugo Tari, Domenico Santoro, Gianluca Trifirò
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract Background Evidences show that around 20% of biosimilar or originator erythropoiesis-stimulating agents (ESAs) users are hyporesponsive. Controversial post-marketing data exist on the predictors of ESA hyporesponsiveness. The aim of this stu
Externí odkaz:
https://doaj.org/article/08381c8e2b2f41c8ad8b4e5225aa1f8b
Autor:
Giuseppe Roberto, Francesco Barone-Adesi, Francesco Giorgianni, Valeria Pizzimenti, Carmen Ferrajolo, Michele Tari, Claudia Bartolini, Roberto Da Cas, Marina Maggini, Stefania Spila-Alegiani, Paolo Francesconi, Gianluca Trifirò, Elisabetta Poluzzi, Fabio Baccetti, Rosa Gini
Publikováno v:
BMC Endocrine Disorders, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background The incretin-based medicines GLP1 analogues (GLP1a) and dipeptidyl peptidase-4 inhibitors (DPP4i) are hypoglycaemic agents licensed for the treatment of type 2 diabetes mellitus (T2DM). Although these drugs possess comparable effi
Externí odkaz:
https://doaj.org/article/04a605883ebf4f0e99f14d8bc520baef
Autor:
Jean Ferrières, Victoria Banks, Demetris Pillas, Francesco Giorgianni, Laurene Gantzer, Beranger Lekens, Lea Ricci, Margaux Dova-Boivin, Jean-Vannak Chauny, Guillermo Villa, Gaelle Désaméricq
Publikováno v:
PLoS ONE, Vol 16, Iss 8 (2021)
Background and aims Untreated Familial Hypercholesterolemia (FH) leads to premature morbidity and mortality. In France, its epidemiology and management are understudied in ambulatory care. We described the clinical profile, pharmacological management
Externí odkaz:
https://doaj.org/article/7d7ab775bcb648d7ba970f75d6c564c9
Publikováno v:
Data in Brief, Vol 20, Iss , Pp 333-336 (2018)
We have performed a proteomics analysis of a human retinal pigment epithelial cell line (ARPE-19), which represents a widely used model for in vitro studies of cellular and molecular mechanisms related to human RPE cells (Dunn et al., 1996; Weigel et
Externí odkaz:
https://doaj.org/article/e4c76347b887431ca425d53db4c00790
Autor:
Cory Parks, Francesco Giorgianni, Byron C. Jones, Sarka Beranova-Giorgianni, Bob M. Moore II, Megan K. Mulligan
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
C57BL/6J (B6) and DBA/2J (D2) inbred mouse strains are highly variable genetically and differ in a large number of behavioral traits related to striatal function, including depression, anxiety, stress response, and response to drugs of abuse. The gen
Externí odkaz:
https://doaj.org/article/263c3f7096374375b376546727fb6a3e
Autor:
Ylenia Ingrasciotta, Janet Sultana, Francesco Giorgianni, Enrica Menditto, Angelo Scuteri, Michele Tari, Daniele Ugo Tari, Giorgio Basile, Gianluca Trifiro'
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222836 (2019)
IntroductionAnalgesics such as non-steroidal anti-inflammatory drugs (NSAIDs), weak and strong opioids are commonly used among elderly persons. The aim of this study was to describe the demographic and clinical characteristics of elderly analgesic us
Externí odkaz:
https://doaj.org/article/f337437fead845e09788b7271529c72e