Zobrazeno 1 - 10
of 381
pro vyhledávání: '"Francesco, Dazzi"'
Autor:
Daniele Avenoso, Fabio Serpenti, Liron Barnea Slonim, Styliani Bouziana, Francesco Dazzi, Guy Hannah, Michelle Kenyon, Varun Mehra, Austin Kulasekararaj, Pramila Krishnamurthy, Mili Naresh Shah, Sharon Lionel, Antonio Pagliuca, Victoria Potter
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 16, Iss 1 (2024)
Background: Allogeneic haematopoietic stem-cell transplant is a potentially curative option for high-risk acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS) patients. Post-transplant cyclophosphamide administration allows for selection
Externí odkaz:
https://doaj.org/article/909489ad418c407599dc7b384cd7f4ba
Autor:
Fabio Serpenti, Daniele Avenoso, Kenyon Michelle, Pramila Krishnamurthy, Varun Mehra, Austin Kulasekararaj, Shreyans Gandhi, Francesco Dazzi, Shah Mili Naresh, Ye Ting Leung, Sandra Anteh, Madson Correia de Farias, Styliani Bouziana, Christianne Bourlon, Oana Diana Dragoi, Tony Pagliuca, Victoria Potter
Publikováno v:
HemaSphere, Vol 7, p e22273e7 (2023)
Externí odkaz:
https://doaj.org/article/8ba754c875d34bf9b4cbd73e6b96dfcc
Autor:
Sandhya Moise, Luigi Dolcetti, Francesco Dazzi, Paul Roach, Lee Buttery, Sheila MacNeil, Nick Medcalf
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 50, Iss 1, Pp 168-176 (2022)
Mesenchymal stromal cells (MSCs) show immunosuppressive effects both via cell-to-cell contact (direct) with immune cells and by producing paracrine factors and extracellular vesicles (indirect). A key challenge in delivering this therapeutic effect i
Externí odkaz:
https://doaj.org/article/553c2c08f92940b3af31d4ab98942208
Autor:
Daniele Avenoso, Amal Alabdulwahab, Michelle Kenyon, Varun Mehra, Pramila Krishnamurthy, Francesco Dazzi, Ye Ting Leung, Sandra Anteh, Mili Naresh Shah, Andrea Kuhnl, Robin Sanderson, Piers Patten, Deborah Yallop, Antonio Pagliuca, Victoria Potter
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 15, Iss 1 (2023)
Background: The second decade of this millennium was characterized by a widespread availability of chimeric antigen receptor T-cell (CAR-T)therapies to treat relapsed and refractory lymphomas. As expected, the role and indication of allogeneic hae
Externí odkaz:
https://doaj.org/article/3ba90f4479c343d691aa52b2eb923b7c
Autor:
Gaia Alberti, Corinne Arsuffi, Alice Pievani, Domenico Salerno, Francesco Mantegazza, Francesco Dazzi, Andrea Biondi, Sarah Tettamanti, Marta Serafini
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In acute myeloid leukemia (AML), malignant stem cells hijack the normal bone marrow niche where they are largely protected from the current therapeutic approaches. Thus, eradicating these progenitors is the ultimate challenge in the treatment of this
Externí odkaz:
https://doaj.org/article/693cec58a41b476bba4843a54cfe5697
Autor:
Vipul Sheth, Victoria Potter, Hugues de Lavallade, Shreyans Gandhi, Austin Kulasekararaj, Pramila Krishnamurthy, Varun Mehra, Francesco Dazzi, Ghulam Mufti, Antonio Pagliuca, Donal Mclornan, Kavita Raj
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 7, Pp 1-6 (2021)
Abstract Pre-emptive DLI (pDLI) is an effective strategy in lowering the risk of relapse without significantly increasing the risk of graft-versus-host disease (GVHD) in the case of T cell lineage mixed chimerism (MC) post allogeneic transplant in he
Externí odkaz:
https://doaj.org/article/6a6208a955b94bbda77e11e80c805e95
Publikováno v:
Cellular & Molecular Immunology. 20:570-582
Mesenchymal stromal cells (MSCs) have been extensively tested for the treatment of numerous clinical conditions and have demonstrated good safety but mixed efficacy. Although this outcome can be attributed in part to the heterogeneity of cell prepara
Autor:
Luise Müller, Antje Tunger, Manja Wobus, Malte von Bonin, Russell Towers, Martin Bornhäuser, Francesco Dazzi, Rebekka Wehner, Marc Schmitz
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mesenchymal stromal cells (MSCs) are characterized by an extraordinary capacity to modulate the phenotype and functional properties of various immune cells that play an essential role in the pathogenesis of inflammatory disorders. Thus, MSCs efficien
Externí odkaz:
https://doaj.org/article/1e1d2d3802e6401c9a6a73cd97374963
Autor:
Tik Shing Cheung, Giuliana Minani Bertolino, Chiara Giacomini, Martin Bornhäuser, Francesco Dazzi, Antonio Galleu
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The immunosuppressive activity of mesenchymal stromal cells (MSCs) in graft versus host disease (GvHD) is well-documented, but their therapeutic benefit is rather unpredictable. Prospective randomized clinical trials remain the only means to address
Externí odkaz:
https://doaj.org/article/7285e8577afd49409d7815f303b6382f
Autor:
Alice Pievani, Samantha Donsante, Chiara Tomasoni, Alessandro Corsi, Francesco Dazzi, Andrea Biondi, Mara Riminucci, Marta Serafini
Publikováno v:
Haematologica, Vol 106, Iss 3 (2020)
Externí odkaz:
https://doaj.org/article/f623bcd922204f9aa92258335d2e916a