Zobrazeno 1 - 10
of 274
pro vyhledávání: '"Francesco, Costanzo"'
Autor:
Vikas Kannojiya, Sara E. Almasy, Jose L. Monclova, Jerry Contreras, Francesco Costanzo, Keefe B. Manning
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Thrombus formation in blood-contacting medical devices is a major concern in the medical device industry, limiting the clinical efficacy of these devices. Further, a locally formed clot within the device has the potential to detach from the surface,
Externí odkaz:
https://doaj.org/article/8034e03797fd4f89b9c3b22300424560
Autor:
Eleonora Vecchio, Salvatore Rotundo, Claudia Veneziano, Antonio Abatino, Ilenia Aversa, Raffaella Gallo, Caterina Giordano, Francesca Serapide, Paolo Fusco, Giuseppe Viglietto, Giovanni Cuda, Francesco Costanzo, Alessandro Russo, Enrico Maria Trecarichi, Carlo Torti, Camillo Palmieri
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background The evolving variants of SARS-CoV-2 may escape immunity from prior infections or vaccinations. It’s vital to understand how immunity adapts to these changes. Both infection and mRNA vaccination induce T cells that target the Spi
Externí odkaz:
https://doaj.org/article/01e07702e8d643888320cc9d61f28fc8
Autor:
Anna Martina Battaglia, Alessandro Sacco, Eleonora Vecchio, Stefania Scicchitano, Lavinia Petriaggi, Emanuele Giorgio, Stefania Bulotta, Sonia Levi, Concetta Maria Faniello, Flavia Biamonte, Francesco Costanzo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Detachment from the extracellular matrix (ECM) is the first step of the metastatic cascade. It is a regulated process involving interaction between tumor cells and tumor microenvironment (TME). Iron is a key micronutrient within the TME
Externí odkaz:
https://doaj.org/article/a767862e1d104b7a931427c300c3cc97
Autor:
Claudia De Vitis, Anna Martina Battaglia, Matteo Pallocca, Gianluca Santamaria, Maria Chiara Mimmi, Alessandro Sacco, Francesca De Nicola, Marco Gaspari, Valentina Salvati, Francesca Ascenzi, Sara Bruschini, Antonella Esposito, Giulia Ricci, Eleonora Sperandio, Alice Massacci, Licia Elvira Prestagiacomo, Andrea Vecchione, Alberto Ricci, Salvatore Sciacchitano, Gerardo Salerno, Deborah French, Ilenia Aversa, Cristina Cereda, Maurizio Fanciulli, Ferdinando Chiaradonna, Egle Solito, Giovanni Cuda, Francesco Costanzo, Gennaro Ciliberto, Rita Mancini, Flavia Biamonte
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-25 (2023)
Abstract Background Metastases are the major cause of cancer-related morbidity and mortality. By the time cancer cells detach from their primary site to eventually spread to distant sites, they need to acquire the ability to survive in non-adherent c
Externí odkaz:
https://doaj.org/article/696bb778472e4725904c07286e9ccd33
Autor:
Anna Martina Battaglia, Alessandro Sacco, Ilenia Aversa, Gianluca Santamaria, Camillo Palmieri, Cirino Botta, Roberto De Stefano, Maurizio Bitetto, Lavinia Petriaggi, Emanuele Giorgio, Concetta Maria Faniello, Francesco Costanzo, Flavia Biamonte
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: The PD-1/PD-L1 axis is hijacked by lung adenocarcinoma (LUAD) cells to escape immune surveillance. PD-L1 expression in LUAD is affected, among others, by the metabolic trafficking between tumor cells and the tumor microenvironment (TME)
Externí odkaz:
https://doaj.org/article/4f26510b81de41ea97f957759a4c4a24
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-24 (2022)
Abstract The movement of fluid into, through, and out of the brain plays an important role in clearing metabolic waste. However, there is controversy regarding the mechanisms driving fluid movement in the fluid-filled paravascular spaces (PVS), and w
Externí odkaz:
https://doaj.org/article/e09f79d5ea46463e81bffb7208f8cae8
Autor:
Saurabh Bhardwaj, Brent A. Craven, Jacob E. Sever, Francesco Costanzo, Scott D. Simon, Keefe B. Manning
Publikováno v:
Frontiers in Medical Technology, Vol 5 (2023)
Acute ischemic stroke (AIS) is a leading cause of mortality that occurs when an embolus becomes lodged in the cerebral vasculature and obstructs blood flow in the brain. The severity of AIS is determined by the location and how extensively emboli bec
Externí odkaz:
https://doaj.org/article/b90c00339d2f40fab2324b7b5acab86e
Autor:
Flavia Biamonte, Cirino Botta, Maria Mazzitelli, Salvatore Rotundo, Enrico Maria Trecarichi, Daniela Foti, Carlo Torti, Giuseppe Viglietto, Daniele Torella, Francesco Costanzo
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-10 (2021)
Abstract Background The Sars-CoV-2 can cause severe pneumonia with multiorgan disease; thus, the identification of clinical and laboratory predictors of the progression towards severe and fatal forms of this illness is needed. Here, we retrospectivel
Externí odkaz:
https://doaj.org/article/ccaf0884f2a64f8eb3193736a55e44f9
Autor:
Stefania Scicchitano, Eleonora Vecchio, Anna Martina Battaglia, Manuela Oliverio, Monica Nardi, Antonio Procopio, Francesco Costanzo, Flavia Biamonte, Maria Concetta Faniello
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 842 (2023)
Oleuropein plays a key role as a pro-oxidant as well as an antioxidant in cancer. In this study, the activity of oleuropein, in an in vitro model of ovarian (OCCs) and breast cancer cells (BCCs) was investigated. Cell viability and cell death were an
Externí odkaz:
https://doaj.org/article/992cbc0108614870ba0b451dc1e1f368
Autor:
Anna Martina Battaglia, Alessandro Sacco, Ida Daniela Perrotta, Maria Concetta Faniello, Mariangela Scalise, Daniele Torella, Sonia Levi, Francesco Costanzo, Flavia Biamonte
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectivesDeveloping novel therapeutic approaches to defeat chemoresistance is the major goal of ovarian cancer research. Induction of ferroptosis has shown promising antitumor effects in ovarian cancer cells, but the existence of still undefined gen
Externí odkaz:
https://doaj.org/article/ef47b42c01b548e8aa944186262a2f9f