Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Francesco, Chiara"'
Autor:
Daniela Di Grazia, Cristina Mirabella, Francesco Chiara, Maura Caudana, Francesco Maximillian Anthony Shelton Agar, Marina Zanatta, Sarah Allegra, Jenni Bertello, Vincenzo Voi, Giovanni Battista Ferrero, Giuliana Abbadessa, Silvia De Francia
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1386 (2024)
Background: Hydroxyurea (HU), also known as hydroxycarbamide, is an oral ribonucleotide reductase inhibitor. In 1999, the United States Food and Drug Administration (FDA) approved HU for the treatment of sickle cell disease (SCD). Since then, it has
Externí odkaz:
https://doaj.org/article/841a7d569c6745f0b87143075996e41d
Akademický článek
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Autor:
Jessica Cusato, Anna Mulasso, Micol Ferrara, Alessandra Manca, Miriam Antonucci, Guido Accardo, Alice Palermiti, Gianluca Bianco, Francesco Chiara, Jacopo Mula, Maria Grazia Maddalone, Maria Cristina Tettoni, Simone Cuomo, Giulia Trevisan, Stefano Bonora, Giovanni Di Perri, Corrado Lupo, Alberto Rainoldi, Antonio D’Avolio
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 518 (2024)
Background: Physical activity could increase the production of oxidative stress biomarkers, affecting the metabolism and excretion of antiretroviral drugs and, consequently, the clinical outcome. Nowadays, people living with HIV (PLWH) are mostly swi
Externí odkaz:
https://doaj.org/article/e70a1f2852ef4b3dbbfb5fee3fde8c23
Autor:
Sarah Allegra, Silvia De Francia, Francesca Turco, Ilenia Bertaggia, Francesco Chiara, Tiziana Armando, Silvana Storto, Maria Valentina Mussa
Publikováno v:
Journal of Xenobiotics, Vol 13, Iss 1, Pp 75-89 (2023)
Background: The use of herbs to treat illnesses was common in all historical eras. Our aim was to describe the phytotherapeutic substances that cancer patients use most commonly, and to determine whether their use can increase side effects. Methods:
Externí odkaz:
https://doaj.org/article/d56fd3b2735b4295babb8470aff798d3
Publikováno v:
Biomedicines, Vol 12, Iss 2, p 265 (2024)
Gender-specific medicine consists of a transversal methodological approach that aims to study the influence of sex and gender on diseases [...]
Externí odkaz:
https://doaj.org/article/30445f40d44e4e46ae959ea2017f0b43
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2478 (2023)
Tyrosine kinase inhibitors work by blocking the tyrosine kinases responsible for the dysregulation of intracellular signalling pathways in tumour cells. This study looked at the impact of age and sex on the levels of imatinib, dasatinib, nilotinib, a
Externí odkaz:
https://doaj.org/article/82d5a72ea6f741d485564061234540f5
Autor:
Sarah Allegra, Francesco Chiara, Marina Zanatta, Giulio Mengozzi, Maria Paola Puccinelli, Silvia De Francia
Publikováno v:
Life, Vol 13, Iss 9, p 1792 (2023)
Teicoplanin, a glycopeptide antibiotic commonly used to treat bacterial infections, was discovered to be active in vitro against SARS-CoV-2. The aim of this study was to assess the levels of teicoplanin and its components in a cohort of adult and ped
Externí odkaz:
https://doaj.org/article/c729b6c551ca4768a1a3dadabe86eeef
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 786 (2023)
Until the last quarter of the 20th century, sex was not recognized as a variable in health research, nor was it believed to be a factor that could affect health and illness. Researchers preferred studying male models for a variety of reasons, such as
Externí odkaz:
https://doaj.org/article/1dfb54ff64cc492e93167145b28a3730
Autor:
Jessica Cusato, Alessandra Manca, Alice Palermiti, Jacopo Mula, Martina Costanzo, Miriam Antonucci, Francesco Chiara, Elisa Delia De Vivo, Domenico Maiese, Micol Ferrara, Stefano Bonora, Giovanni Di Perri, Antonio D’Avolio, Andrea Calcagno
Publikováno v:
Antioxidants, Vol 12, Iss 5, p 1133 (2023)
An uncontrolled inflammatory response during SARS-CoV-2 infection has been highlighted in several studies. This seems to be due to pro-inflammatory cytokines whose production could be regulated by vitamin D, ROS production or mitogen-activated protei
Externí odkaz:
https://doaj.org/article/ce6de71ba45f4990a65051cbc7ad378a
Autor:
Jessica Cusato, Alessandra Manca, Alice Palermiti, Jacopo Mula, Martina Costanzo, Miriam Antonucci, Mattia Trunfio, Silvia Corcione, Francesco Chiara, Elisa Delia De Vivo, Alice Ianniello, Micol Ferrara, Giovanni Di Perri, Francesco Giuseppe De Rosa, Antonio D’Avolio, Andrea Calcagno
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1459 (2023)
Background: COVID-19 is characterized by an uncontrolled inflammatory response with high pro-inflammatory cytokine production through the activation of intracellular pathways, such as mitogen-activated protein kinase (MAPK). Viruses are able to explo
Externí odkaz:
https://doaj.org/article/677fe13d0612486e96fe99c24c6d73b4