Zobrazeno 1 - 10
of 259
pro vyhledávání: '"Francesco, Beguinot"'
Autor:
Paola Mirra, Alessia Parascandolo, Graziella Marino, Federica D’Alterio, Lorenza Zinna, Antonella Desiderio, Giuseppe Patitucci, Giulia Anna Carmen Vita, Valentina Condelli, Sabino Russi, Francesco D’Andrea, Francesco Beguinot, Claudia Miele, Pietro Formisano, Vittoria D’Esposito
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-9 (2024)
Abstract The adipose tissue (AT) surrounding breast cancer (BC) plays a pivotal role in cancer progression and represents an optimal source for new biomarker discovery. The aim of this work was to investigate whether specific AT factors may have prog
Externí odkaz:
https://doaj.org/article/011d546ef709475da91b0b7f85549e11
Autor:
Maria Rosaria Ambrosio, Michiel Adriaens, Kasper Derks, Teresa Migliaccio, Valerio Costa, Domenico Liguoro, Simona Cataldi, Vittoria D’Esposito, Giovanni Maneli, Rita Bassolino, Simone Di Paola, Marinella Pirozzi, Fabrizio Schonauer, Francesco D’Andrea, Francesco Beguinot, Ilja Arts, Pietro Formisano
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-24 (2024)
Abstract An established hallmark of cancer cells is metabolic reprogramming, largely consisting in the exacerbated glucose uptake. Adipocytes in the tumor microenvironment contribute toward breast cancer (BC) progression and are highly responsive to
Externí odkaz:
https://doaj.org/article/5addcdb6537e469486ffd50c9fcd8aa2
Autor:
Antonella Desiderio, Monica Pastorino, Michele Campitelli, Michele Longo, Claudia Miele, Raffaele Napoli, Francesco Beguinot, Gregory Alexander Raciti
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Cardiovascular diseases (CVD) affect over half a billion people worldwide and are the leading cause of global deaths. In particular, due to population aging and worldwide spreading of risk factors, the prevalence of heart failure
Externí odkaz:
https://doaj.org/article/22874d2adca3478a96d405b07b92ac66
Autor:
Michele Longo, Federica Zatterale, Rosa Spinelli, Jamal Naderi, Luca Parrillo, Pasqualina Florese, Cecilia Nigro, Alessia Leone, Augusta Moccia, Antonella Desiderio, Gregory A. Raciti, Claudia Miele, Ulf Smith, Francesco Beguinot
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-24 (2023)
Abstract Background First-degree relatives of type 2 diabetics (FDR) exhibit a high risk of developing type 2 diabetes (T2D) and feature subcutaneous adipocyte hypertrophy, independent of obesity. In FDR, adipose cell abnormalities contribute to earl
Externí odkaz:
https://doaj.org/article/67d0a5fc91c74ab8832d99e8826746b5
Autor:
Rosa Spinelli, Ritesh Kumar Baboota, Silvia Gogg, Francesco Beguinot, Matthias Blüher, Annika Nerstedt, Ulf Smith
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Cell senescence (CS) is at the nexus between aging and associated chronic disorders, and aging increases the burden of CS in all major metabolic tissues. However, CS is also increased in adult obesity, type 2 diabetes (T2D), and nonalcoholic fatty li
Externí odkaz:
https://doaj.org/article/385566925a69478882f3d28fa1bafa44
Autor:
Alessia Parascandolo, Michele Francesco Di Tolla, Domenico Liguoro, Manuela Lecce, Saverio Misso, Fabiana Micieli, Maria Rosaria Ambrosio, Serena Cabaro, Francesco Beguinot, Alessandra Pelagalli, Vittoria D’Esposito, Pietro Formisano
Publikováno v:
Stem Cells International, Vol 2023 (2023)
Platelet products are commonly used in regenerative medicine due to their effects on the acceleration and promotion of wound healing, reduction of bleeding, synthesis of new connective tissue, and revascularization. Furthermore, a novel approach for
Externí odkaz:
https://doaj.org/article/7f6deae0e73443f2bcc30f9e0226551a
Autor:
Serena Cabaro, Vittoria D’Esposito, Tiziana Di Matola, Silvia Sale, Michele Cennamo, Daniela Terracciano, Valentina Parisi, Francesco Oriente, Giuseppe Portella, Francesco Beguinot, Luigi Atripaldi, Mario Sansone, Pietro Formisano
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract In Europe, multiple waves of infections with SARS-CoV-2 (COVID-19) have been observed. Here, we have investigated whether common patterns of cytokines could be detected in individuals with mild and severe forms of COVID-19 in two pandemic wa
Externí odkaz:
https://doaj.org/article/850007cd1b0c441cbe67e6f28d740ad7
Autor:
Domenico Conza, Paola Mirra, Francesca Fiory, Luigi Insabato, Antonella Nicolò, Francesco Beguinot, Luca Ulianich
Publikováno v:
Cells, Vol 12, Iss 17, p 2182 (2023)
The biguanide drug metformin is widely used in type 2 diabetes mellitus therapy, due to its ability to decrease serum glucose levels, mainly by reducing hepatic gluconeogenesis and glycogenolysis. A considerable number of studies have shown that metf
Externí odkaz:
https://doaj.org/article/6ecf599bcba3436e8282ee0c4a96c615
Autor:
Luca Parrillo, Rosa Spinelli, Michele Longo, Federica Zatterale, Gianluca Santamaria, Alessia Leone, Michele Campitelli, Gregory Alexander Raciti, Francesco Beguinot
Publikováno v:
Cells, Vol 12, Iss 16, p 2090 (2023)
The transcription factor HOXA5, from the HOX gene family, has long been studied due to its critical role in physiological activities in normal cells, such as organ development and body patterning, and pathological activities in cancer cells. Nonethel
Externí odkaz:
https://doaj.org/article/862612a4bea44cc08d945e65e8d35417
Autor:
Marco Milone, Antonella Desiderio, Nunzio Velotti, Michele Manigrasso, Sara Vertaldi, Umberto Bracale, Michele D’Ambra, Giuseppe Servillo, Giuseppe De Simone, Fatima Domenica Elisa De Palma, Giuseppe Perruolo, Gregory Alexander Raciti, Claudia Miele, Francesco Beguinot, Giovanni Domenico De Palma
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract No clear consensus on the need to perform an intracorporeal anastomosis (IA) after laparoscopic right colectomy is currently available. One of the potential benefits of intracorporeal anastomosis may be a reduction in surgical stress. Herein
Externí odkaz:
https://doaj.org/article/4c8ab5a4e9e14868a773269f5bec8b0d