Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Francesca del Bufalo"'
Autor:
Mattia Algeri, Michele Massa, Daria Pagliara, Valentina Bertaina, Federica Galaverna, Ilaria Pili, Giuseppina Li Pira, Roberto Carta, Francesco Quagliarella, Rita M. Pinto, Chiara Rosignoli, Barbarella Lucarelli, Maria G. Cefalo, Emilia Boccieri, Francesca Benini, Francesca Del Bufalo, Marco Becilli, Pietro Merli, Gerhard Zugmaier, Franco Locatelli
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Blinatumomab has remarkable efficacy in patients with relapsed/refractory (r/r) or measurable residual disease (MRD)-positive B-cell acute lymphoblastic leukemia (B-ALL). In many patients, blinatumomab treatment is followed by allogeneic hematopoieti
Externí odkaz:
https://doaj.org/article/af38db97bf884293a331035c0023a21c
Autor:
Lucia Pedace, Simone Pizzi, Luana Abballe, Maria Vinci, Celeste Antonacci, Sara Patrizi, Claudia Nardini, Francesca Del Bufalo, Sabrina Rossi, Giulia Pericoli, Francesca Gianno, Zein Mersini Besharat, Luca Tiberi, Angela Mastronuzzi, Elisabetta Ferretti, Marco Tartaglia, Franco Locatelli, Andrea Ciolfi, Evelina Miele
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract In vitro models of pediatric brain tumors (pBT) are instrumental for better understanding the mechanisms contributing to oncogenesis and testing new therapies; thus, ideally, they should recapitulate the original tumor. We applied DNA methyl
Externí odkaz:
https://doaj.org/article/3e271e6514f4435baadb82be0810cbf5
Autor:
Federica Galaverna, Sara Flamini, Carmen Dolores De Luca, Ilaria Pili, Emilia Boccieri, Francesca Benini, Francesco Quagliarella, Chiara Rosignoli, Marco Rosichini, Shirley Genah, Marialuigia Catanoso, Antonella Cardinale, Gabriele Volpe, Marianna Coccetti, Angela Pitisci, Giuseppina Li Pira, Roberto Carta, Barbarella Lucarelli, Francesca Del Bufalo, Valentina Bertaina, Marco Becilli, Daria Pagliara, Mattia Algeri, Pietro Merli, Franco Locatelli, Enrico Velardi
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Mucosal-associated invariant T (MAIT) cells are innate-like T-cells implicated in the response to fungal and bacterial infections. Their contribution to restoring T-cell immunity and influencing hematopoietic stem cell transplant (HSCT) outcomes rema
Externí odkaz:
https://doaj.org/article/25f2a926a6bd46bd88584bb02e4a9e44
Publikováno v:
Haematologica, Vol 109, Iss 6 (2024)
Chimeric antigen receptor (CAR) T-cell therapy has emerged as a breakthrough cancer therapy over the past decade. Remarkable outcomes in B-cell lymphoproliferative disorders and multiple myeloma have been reported in both pivotal trials and real-word
Externí odkaz:
https://doaj.org/article/445a1483847e45a2a3cbca19bbf3cda5
Autor:
Maria Antonietta De Ioris, Francesco Fabozzi, Francesca Del Bufalo, Giada Del Baldo, Maria Felicia Villani, Maria Giuseppina Cefalo, Maria Carmen Garganese, Alessandra Stracuzzi, Federica Tangari, Arturo Maria Greco, Isabella Giovannoni, Roberto Carta, Maria Luisa D’Andrea, Angela Mastronuzzi, Franco Locatelli
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-5 (2023)
Abstract The prognosis of relapsed/refractory (R/R) neuroblastoma (NB) is dismal, calling for new therapeutic strategies. Venetoclax (VEN) is a highly selective, potent, orally bioavailable, BCL-2 inhibitor small-molecule that showed a synergistic ef
Externí odkaz:
https://doaj.org/article/d9a3f4ab567b4cb2b052b48621dda13d
Autor:
Simona Manni, Francesca Del Bufalo, Pietro Merli, Domenico Alessandro Silvestris, Marika Guercio, Simona Caruso, Sofia Reddel, Laura Iaffaldano, Michele Pezzella, Stefano Di Cecca, Matilde Sinibaldi, Alessio Ottaviani, Maria Cecilia Quadraccia, Mariasole Aurigemma, Andrea Sarcinelli, Roselia Ciccone, Zeinab Abbaszadeh, Manuela Ceccarelli, Rita De Vito, Maria Chiara Lodi, Maria Giuseppina Cefalo, Angela Mastronuzzi, Biagio De Angelis, Franco Locatelli, Concetta Quintarelli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Chimeric antigen receptor T (CAR-T) cell therapy may achieve long-lasting remission in patients with B-cell malignancies not responding to conventional therapies. However, potentially severe and hard-to-manage side effects, including cytokin
Externí odkaz:
https://doaj.org/article/e13fedf5b3e94ec1a443079d5e0501e7
Autor:
Simona Caruso, Biagio De Angelis, Francesca Del Bufalo, Roselia Ciccone, Samantha Donsante, Gabriele Volpe, Simona Manni, Marika Guercio, Michele Pezzella, Laura Iaffaldano, Domenico Alessandro Silvestris, Matilde Sinibaldi, Stefano Di Cecca, Angela Pitisci, Enrico Velardi, Pietro Merli, Mattia Algeri, Mariachiara Lodi, Valeria Paganelli, Marta Serafini, Mara Riminucci, Franco Locatelli, Concetta Quintarelli
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-19 (2022)
Abstract Background Paediatric acute myeloid leukaemia (AML) is characterized by poor outcomes in patients with relapsed/refractory disease, despite the improvements in intensive standard therapy. The leukaemic cells of paediatric AML patients show h
Externí odkaz:
https://doaj.org/article/a538e2a7f35741f4b65eb6ac393adde9
Autor:
Giada Del Baldo, Francesca Del Bufalo, Claudia Pinacchio, Andrea Carai, Concetta Quintarelli, Biagio De Angelis, Pietro Merli, Antonella Cacchione, Franco Locatelli, Angela Mastronuzzi
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Childhood malignant brain tumors remain a significant cause of death in the pediatric population, despite the use of aggressive multimodal treatments. New therapeutic approaches are urgently needed for these patients in order to improve prognosis, wh
Externí odkaz:
https://doaj.org/article/4dd8274939b54ffea9f0c941d210bd49
Autor:
Nicola Tumino, Gerrit Weber, Francesca Besi, Francesca Del Bufalo, Valentina Bertaina, Paola Paci, Linda Quatrini, Laura Antonucci, Matilde Sinibaldi, Concetta Quintarelli, Enrico Maggi, Biagio De Angelis, Franco Locatelli, Lorenzo Moretta, Paola Vacca, Ignazio Caruana
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-7 (2021)
Abstract The outcome of patients affected by high-risk or metastatic neuroblastoma (NB) remains grim, with ≥ 50% of the children experiencing relapse or progression of the disease despite multimodal, intensive treatment. In order to identify new st
Externí odkaz:
https://doaj.org/article/51f0504736a347c6a8f2d674f1b4901c
Autor:
Pietro Merli, Daria Pagliara, Tommaso Mina, Valentina Bertaina, Giuseppina Li Pira, Stefania Lazzaro, Simone Biagini, Federica Galaverna, Luisa Strocchio, Roberto Carta, Maria Luigia Catanoso, Francesco Quagliarella, Marco Becilli, Emilia Boccieri, Francesca Del Bufalo, Arianna Panigari, Annalisa Agostini, Lucia Pedace, Simone Pizzi, Cesare Perotti, Mattia Algeri, Marco Zecca, Franco Locatelli
Publikováno v:
Haematologica, Vol 107, Iss 12 (2022)
Externí odkaz:
https://doaj.org/article/0dd6b69d88bb495aad7ddaebc370a058