Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Francesca de Nicola"'
Autor:
Giacomo Corleone, Cristina Sorino, Matteo Caforio, Stefano Di Giovenale, Francesca De Nicola, Frauke Goeman, Valentina Bertaina, Angela Pitisci, Clelia Cortile, Franco Locatelli, Valentina Folgiero, Maurizio Fanciulli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-19 (2024)
Abstract Background Enhancer reprogramming plays a significant role in the heterogeneity of cancer. However, we have limited knowledge about the impact of chromatin remodeling in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) patients, and h
Externí odkaz:
https://doaj.org/article/e6a90fbd8fa04cd28df478d56fad768a
Autor:
Simona D’Aguanno, Matteo Brignone, Stefano Scalera, Martina Chiacchiarini, Marta Di Martile, Elisabetta Valentini, Francesca De Nicola, Alessia Ricci, Fabio Pelle, Claudio Botti, Marcello Maugeri-Saccà, Donatella Del Bufalo
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Introduction Bcl-2 and Bcl-xL are the most studied anti-apoptotic members of Bcl-2 family proteins. We previously characterized both of them, not only for their role in regulating apoptosis and resistance to therapy in cancer cells, but also
Externí odkaz:
https://doaj.org/article/121a571fcff840baa7b067d1e9d90e7a
Autor:
Francesca Ascenzi, Antonella Esposito, Sara Bruschini, Valentina Salvati, Claudia De Vitis, Valeria De Arcangelis, Giulia Ricci, Angiolina Catizione, Simona di Martino, Simonetta Buglioni, Massimiliano Bassi, Federico Venuta, Francesca De Nicola, Alice Massacci, Isabella Grassucci, Matteo Pallocca, Alberto Ricci, Maurizio Fanciulli, Gennaro Ciliberto, Rita Mancini
Publikováno v:
Cell Death and Disease, Vol 15, Iss 4, Pp 1-13 (2024)
Abstract Scientific literature supports the evidence that cancer stem cells (CSCs) retain inside low reactive oxygen species (ROS) levels and are, therefore, less susceptible to cell death, including ferroptosis, a type of cell death dependent on iro
Externí odkaz:
https://doaj.org/article/f6724e91968642fc9b2fd2f144f72248
Autor:
Belinda Palermo, Ornella Franzese, Giuseppe Frisullo, Lorenzo D’Ambrosio, Mariangela Panetta, Giulia Campo, Daniel D’Andrea, Isabella Sperduti, Francesca De Nicola, Frauke Goeman, Filippo Gallina, Paolo Visca, Francesco Facciolo, Paola Nisticò
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-26 (2023)
Abstract Background Immune checkpoint blockade (ICB) has significantly prolonged survival of non-small cell lung cancer (NSCLC) patients, although most patients develop mechanisms of resistance. Recently single-cell RNA-sequencing (scRNA-Seq) reveale
Externí odkaz:
https://doaj.org/article/571ea82633d4428bb111cb168f3d2393
Autor:
Patrizio Giacomini, Fabio Valenti, Matteo Allegretti, Matteo Pallocca, Francesca De Nicola, Ludovica Ciuffreda, Maurizio Fanciulli, Stefano Scalera, Simonetta Buglioni, Elisa Melucci, Beatrice Casini, Mariantonia Carosi, Edoardo Pescarmona, Elena Giordani, Francesca Sperati, Nicoletta Jannitti, Martina Betti, Marcello Maugeri-Saccà, Fabiana Letizia Cecere, Veronica Villani, Andrea Pace, Marialuisa Appetecchia, Patrizia Vici, Antonella Savarese, Eriseld Krasniqi, Virginia Ferraresi, Michelangelo Russillo, Alessandra Fabi, Lorenza Landi, Gabriele Minuti, Federico Cappuzzo, Massimo Zeuli, Gennaro Ciliberto
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Molecular Tumor Boards (MTB) operating in real-world have generated limited consensus on good practices for accrual, actionable alteration mapping, and outcome metrics. These topics are addressed herein in 124 MTB patients, all re
Externí odkaz:
https://doaj.org/article/8cd52fa220ea4469af2300403ba19259
Autor:
Francesca Di Modugno, Anna Di Carlo, Sheila Spada, Belinda Palermo, Lorenzo D'Ambrosio, Daniel D'Andrea, Gaia Morello, Beatrice Belmonte, Isabella Sperduti, Vittoria Balzano, Enzo Gallo, Roberta Melchionna, Mariangela Panetta, Giulia Campo, Francesca De Nicola, Frauke Goeman, Barbara Antoniani, Silvia Carpano, Gianmaria Frigè, Sarah Warren, Filippo Gallina, Diether Lambrechts, Jieyi Xiong, Benjamin G. Vincent, Nathan Wheeler, Dante S. Bortone, Federico Cappuzzo, Francesco Facciolo, Claudio Tripodo, Paolo Visca, Paola Nisticò
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105003- (2024)
Summary: Background: Tertiary Lymphoid Structures (TLS) correlate with positive outcomes in patients with NSCLC and the efficacy of immune checkpoint blockade (ICB) in cancer. The actin regulatory protein hMENA undergoes tissue-specific splicing, pro
Externí odkaz:
https://doaj.org/article/5fd739eb5c1748ce8a0ed4de3fe1985a
Autor:
Claudia Fierro, Veronica Gatti, Veronica La Banca, Sara De Domenico, Stefano Scalera, Giacomo Corleone, Maurizio Fanciulli, Francesca De Nicola, Alessandro Mauriello, Manuela Montanaro, George A. Calin, Gerry Melino, Angelo Peschiaroli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The transcription factor ΔNp63 regulates epithelial stem cell function and maintains the integrity of stratified epithelial tissues by acting as transcriptional repressor or activator towards a distinct subset of protein-coding genes and mi
Externí odkaz:
https://doaj.org/article/eafc788a7a7545c69bc62a7a9637dd3d
Autor:
Veronica Villani, Beatrice Casini, Antonio Tanzilli, Mario Lecce, Fabrizio Rasile, Stefano Telera, Andrea Pace, Francesca Piludu, Irene Terrenato, Francesca Rollo, Francesca De Nicola, Maurizio Fanciulli, Matteo Pallocca, Gennaro Ciliberto, Mariantonia Carosi
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background This study aimed to characterize the genetic profile of patients with glioma and discuss the impact of next-generation sequencing in glioma diagnosis and treatment. Methods Between 2019 and 2022, we analyzed the genetic profile of
Externí odkaz:
https://doaj.org/article/7f1c7a725e56429db1729cd41d90b0c7
Autor:
Claudia De Vitis, Anna Martina Battaglia, Matteo Pallocca, Gianluca Santamaria, Maria Chiara Mimmi, Alessandro Sacco, Francesca De Nicola, Marco Gaspari, Valentina Salvati, Francesca Ascenzi, Sara Bruschini, Antonella Esposito, Giulia Ricci, Eleonora Sperandio, Alice Massacci, Licia Elvira Prestagiacomo, Andrea Vecchione, Alberto Ricci, Salvatore Sciacchitano, Gerardo Salerno, Deborah French, Ilenia Aversa, Cristina Cereda, Maurizio Fanciulli, Ferdinando Chiaradonna, Egle Solito, Giovanni Cuda, Francesco Costanzo, Gennaro Ciliberto, Rita Mancini, Flavia Biamonte
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-25 (2023)
Abstract Background Metastases are the major cause of cancer-related morbidity and mortality. By the time cancer cells detach from their primary site to eventually spread to distant sites, they need to acquire the ability to survive in non-adherent c
Externí odkaz:
https://doaj.org/article/696bb778472e4725904c07286e9ccd33
Autor:
Sarah Warren, Paola Nisticò, Federico Cappuzzo, Federica Marchesi, Isabella Sperduti, Silvia Carpano, Francesca De Nicola, Frauke Goeman, Lorenzo D'Ambrosio, Vanesa Gregorc, Claudio Tripodo, Vincenzo Russo, Paolo Visca, Francesca Paolini, Paola Trono, Annalisa Tocci, Belinda Palermo, Anna Di Carlo, Daniel D'Andrea, Francesca Di Modugno, Giacomo Corleone, Mariangela Panetta, Silvia Baldari, Paolo Zucali
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background Understanding how cancer signaling pathways promote an immunosuppressive program which sustains acquired or primary resistance to immune checkpoint blockade (ICB) is a crucial step in improving immunotherapy efficacy. Among the pathways th
Externí odkaz:
https://doaj.org/article/fd3fa3f807bf4ff6ad2b89290cb99193