Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Francesca Zanderigo"'
Autor:
Granville J. Matheson, Liner Ge, Mengyu Zhang, Bingyu Sun, Yuqi Tu, Francesca Zanderigo, Anton Forsberg Morèn, R. Todd Ogden
Publikováno v:
EJNMMI Physics, Vol 10, Iss 1, Pp 1-17 (2023)
Abstract Full quantification of Positron Emission Tomography (PET) requires an arterial input function (AIF) for measurement of certain targets, or using particular radiotracers, or for the quantification of specific outcome measures. The AIF represe
Externí odkaz:
https://doaj.org/article/1496c1712d2c403a8413f54817a43de8
Publikováno v:
NeuroImage, Vol 249, Iss , Pp 118901- (2022)
Introduction: Full quantification of positron emission tomography (PET) data requires an input function. This generally means arterial blood sampling, which is invasive, labor-intensive and burdensome. There is no current, standardized method to full
Externí odkaz:
https://doaj.org/article/fa3b69459de34402a6a7fd1354994ce4
Autor:
Peristera-Ioanna Petropoulou, Ioanna Mosialou, Steven Shikhel, Lihong Hao, Konstantinos Panitsas, Brygida Bisikirska, Na Luo, Fabiana Bahna, Jongho Kim, Patrick Carberry, Francesca Zanderigo, Norman Simpson, Mihran Bakalian, Suham Kassir, Lawrence Shapiro, Mark D Underwood, Christina M May, Kiran Kumar Soligapuram Sai, Matthew J Jorgensen, Cyrille B Confavreux, Sue Shapses, Blandine Laferrère, Akiva Mintz, J John Mann, Mishaela Rubin, Stavroula Kousteni
Publikováno v:
eLife, Vol 9 (2020)
In the mouse, the osteoblast-derived hormone Lipocalin-2 (LCN2) suppresses food intake and acts as a satiety signal. We show here that meal challenges increase serum LCN2 levels in persons with normal or overweight, but not in individuals with obesit
Externí odkaz:
https://doaj.org/article/b2734d3dbbc54f4eb86187281ddbff78
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Background Positron emission tomography (PET) is a molecular imaging technology that enables in vivo quantification of metabolic activity or receptor density, among other applications. Examples of applications of PET imaging in neuroscience
Externí odkaz:
https://doaj.org/article/2a4623b1337f4c2b8a3655c977f28037
Autor:
Jaya Prabhakaran, Christine DeLorenzo, Francesca Zanderigo, Gitte M Knudsen, Nic Gilling, Mali Pratap, Matthew J Jorgensen, James Daunais, Jay R Kaplan, Ramin V Parsey, J John Mann, Dileep Kumar
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 22, Iss 1 (2019)
Purpose: 5-HT2AR exists in high and low affinity states. Agonist PET tracers measure binding to the active high affinity site and thus provide a functionally relevant measure of the receptor. Limited in vivo data have been reported so far for a compa
Externí odkaz:
https://doaj.org/article/27366db00a254ebda30d1fc2ed01fa13
Autor:
Andrei Molotkov, Patrick Carberry, Martin A. Dolan, Simon Joseph, Sidney Idumonyi, Shunichi Oya, John Castrillon, Elisa E. Konofagou, Mikhail Doubrovin, Glenn J. Lesser, Francesca Zanderigo, Akiva Mintz
Publikováno v:
Pharmaceutics, Vol 13, Iss 3, p 405 (2021)
Glioblastoma (GBM) is the most common primary adult brain malignancy with an extremely poor prognosis and a median survival of fewer than two years. A key reason for this high mortality is that the blood–brain barrier (BBB) significantly restricts
Externí odkaz:
https://doaj.org/article/e7a03a71ccb34b5b9dc1a3d520651608
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176636 (2017)
BACKGROUND AND AIM:Estimation of a PET tracer's non-displaceable distribution volume (VND) is required for quantification of specific binding to its target of interest. VND is generally assumed to be comparable brain-wide and is determined either fro
Externí odkaz:
https://doaj.org/article/af86879bdf0444dfb3e4005e8dc6867d
Autor:
J. S. Dileep Kumar, Bing Bai, Francesca Zanderigo, Christine DeLorenzo, Jaya Prabhakaran, Ramin V. Parsey, J. John Mann
Publikováno v:
Molecules, Vol 23, Iss 8, p 1929 (2018)
COX-2 selective inhibitors (COXIBs) are non-steroidal anti-inflammatory drugs (NSAIDs), with fewer side effects compared with non-selective NSAIDs, and are used for the treatment of arthritis, headaches, and other inflammatory diseases of the brain a
Externí odkaz:
https://doaj.org/article/4e1284494a2f40bc989e1db046d513f8
Autor:
Elizabeth A. Bartlett, Francesca Zanderigo, Barbara Stanley, Tse-Hwei Choo, Hanga C. Galfalvy, Spiro P. Pantazatos, M. Elizabeth Sublette, Jeffrey M. Miller, Maria A. Oquendo, J. John Mann
Publikováno v:
European Neuropsychopharmacology. 70:1-13
Autor:
Ainsley K. Burke, Francesca Zanderigo, Mohammad Lesanpezeshki, Nadine M. Melhem, Elizabeth Bartlett, Jeffrey M. Miller, J. John Mann, David A. Brent, Pantazatos S
Publikováno v:
Mol Psychiatry
BACKGROUND: Mood disorders and suicidal behavior have moderate heritability and are associated with altered corticolimbic serotonin 1A receptor (5-HT1A) binding potential. However, it is unclear whether these alterations reflect heritable risk or epi