Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Francesca Tuorto"'
Autor:
Aynur Sönmez, Rasem Mustafa, Salome T. Ryll, Francesca Tuorto, Ludivine Wacheul, Donatella Ponti, Christian Litke, Tanja Hering, Kerstin Kojer, Jenniver Koch, Claudia Pitzer, Joachim Kirsch, Andreas Neueder, Grzegorz Kreiner, Denis L. J. Lafontaine, Michael Orth, Birgit Liss, Rosanna Parlato
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-12 (2021)
Abstract Transcriptional and cellular-stress surveillance deficits are hallmarks of Huntington’s disease (HD), a fatal autosomal-dominant neurodegenerative disorder caused by a pathological expansion of CAG repeats in the Huntingtin (HTT) gene. The
Externí odkaz:
https://doaj.org/article/ef5389a9059145348fc5353ee8922ca1
Autor:
Marius Costel Alupei, Pallab Maity, Philipp Ralf Esser, Ioanna Krikki, Francesca Tuorto, Rosanna Parlato, Marianna Penzo, Adrian Schelling, Vincent Laugel, Lorenzo Montanaro, Karin Scharffetter-Kochanek, Sebastian Iben
Publikováno v:
Cell Reports, Vol 23, Iss 6, Pp 1612-1619 (2018)
Summary: Retarded growth and neurodegeneration are hallmarks of the premature aging disease Cockayne syndrome (CS). Cockayne syndrome proteins take part in the key step of ribosomal biogenesis, transcription of RNA polymerase I. Here, we identify a m
Externí odkaz:
https://doaj.org/article/98f1ad7eb84b485e8b920342542da1cf
Autor:
Sarah Jesse, Hanna Bayer, Marius C. Alupei, Martina Zügel, Medhanie Mulaw, Francesca Tuorto, Silke Malmsheimer, Karmveer Singh, Jürgen Steinacker, Uwe Schumann, Albert C. Ludolph, Karin Scharffetter-Kochanek, Anke Witting, Patrick Weydt, Sebastian Iben
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract PGC-1α is a versatile inducer of mitochondrial biogenesis and responsive to the changing energy demands of the cell. As mitochondrial ATP production requires proteins that derive from translation products of cytosolic ribosomes, we asked wh
Externí odkaz:
https://doaj.org/article/2478132ea7814397b8b16d705aad350d
Autor:
Patti Hayes, Claire Fergus, Magda Ghanim, Cansu Cirzi, Lyubomyr Burtnyak, Callum J. McGrenaghan, Francesca Tuorto, Derek P. Nolan, Vincent P. Kelly
Publikováno v:
Nutrients, Vol 12, Iss 3, p 871 (2020)
Queuine is a eukaryotic micronutrient, derived exclusively from eubacteria. It is incorporated into both cytosolic and mitochondrial transfer RNA to generate a queuosine nucleotide at position 34 of the anticodon loop. The transfer RNA of primary tum
Externí odkaz:
https://doaj.org/article/caeb5fc697d446d3913f867e7faf2649
Autor:
Francesca Tuorto, Frank Lyko
Publikováno v:
Open Biology, Vol 6, Iss 12 (2016)
RNA modifications are emerging as an additional regulatory layer on top of the primary RNA sequence. These modifications are particularly enriched in tRNAs where they can regulate not only global protein translation, but also protein translation at t
Externí odkaz:
https://doaj.org/article/cd1ac99e85e942d891fbc1d5a8354448
Autor:
Jafar Kiani, Valérie Grandjean, Reinhard Liebers, Francesca Tuorto, Hossein Ghanbarian, Frank Lyko, François Cuzin, Minoo Rassoulzadegan
Publikováno v:
PLoS Genetics, Vol 9, Iss 5, p e1003498 (2013)
RNA-mediated transmission of phenotypes is an important way to explain non-Mendelian heredity. We have previously shown that small non-coding RNAs can induce hereditary epigenetic variations in mice and act as the transgenerational signalling molecul
Externí odkaz:
https://doaj.org/article/24a14fbbd6394eb8a6c6c8f23599bebd
Autor:
Johanna E Plehn, Mark Helm, Larissa Bessler, Kristina Friedland, Marko Jörg, Cansu Cirzi, Francesca Tuorto, Florian Richter, Jasmin Hertler
Publikováno v:
Nucleic Acids Research. 50:4201-4215
The accurate definition of an epitranscriptome is endangered by artefacts resulting from RNA degradation after cell death, a ubiquitous yet little investigated process. By tracing RNA marker modifications through tissue preparation protocols, we iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5cfff8705835876b424b1bd9248c70
https://doi.org/10.1093/nar/gkab1150
https://doi.org/10.1093/nar/gkab1150
Autor:
Larissa Bessler, Navpreet Kaur, Lea-Marie Vogt, Laurin Flemmich, Carmen Siebenaller, Marie-Luise Winz, Francesca Tuorto, Ronald Micura, Ann E Ehrenhofer-Murray, Mark Helm
Publikováno v:
Nucleic acids research. 50(18)
Substitution of the queuine nucleobase precursor preQ1 by an azide-containing derivative (azido-propyl-preQ1) led to incorporation of this clickable chemical entity into tRNA via transglycosylation in vitro as well as in vivo in Escherichia coli, Sch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260857f539f2ae8de9afedd7738c5729
https://pubmed.ncbi.nlm.nih.gov/36169220
https://pubmed.ncbi.nlm.nih.gov/36169220
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2428
Ribosome profiling methods are based on high-throughput sequencing of ribosome-protected mRNA footprints and allow to study in detail translational changes. Bioinformatic and statistical tools are necessary to analyze sequencing data. Here, we descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb8ec3b5d22e4ddf9c4a5ca1e92a4a53
https://pubmed.ncbi.nlm.nih.gov/35171478
https://pubmed.ncbi.nlm.nih.gov/35171478
Publikováno v:
Methods in Molecular Biology ISBN: 9781071619742
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12d0ca579f33e48cda078e65bb53b0cf
https://doi.org/10.1007/978-1-0716-1975-9_9
https://doi.org/10.1007/978-1-0716-1975-9_9
