Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Francesca Scionti"'
Autor:
Samantha Maurotti, Nadia Geirola, Miriam Frosina, Angela Mirarchi, Francesca Scionti, Rosario Mare, Tiziana Montalcini, Arturo Pujia, Luca Tirinato
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Over the past 10 years, the biological role of lipid droplets (LDs) has gained significant attention in the context of both physiological and pathological conditions. Considerable progress has been made in elucidating key aspects of these organelles,
Externí odkaz:
https://doaj.org/article/3a939991dee04baea132365ddc3c9a55
Autor:
Nicoletta Staropoli, Francesca Scionti, Valentina Farenza, Federica Falcone, Francesco Luciano, Maria Renne, Maria Teresa Di Martino, Domenico Ciliberto, Ludovica Tedesco, Antonella Crispino, Caterina Labanca, Maria Cucè, Stefania Esposito, Giuseppe Agapito, Mario Cannataro, Pierfrancesco Tassone, Pierosandro Tagliaferri, Mariamena Arbitrio
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116478- (2024)
Background: Long-term survival induced by anticancer treatments discloses emerging frailty among breast cancer (BC) survivors. Trastuzumab-induced cardiotoxicity (TIC) is reported in at least 5% of HER2+BC patients. However, TIC mechanism remains unc
Externí odkaz:
https://doaj.org/article/525912e00ae24511943ab9978d60570d
Autor:
Moomna Afzal, Francesca Greco, Federico Quinzi, Francesca Scionti, Samantha Maurotti, Tiziana Montalcini, Annamaria Mancini, Pasqualina Buono, Gian Pietro Emerenziani
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6813 (2024)
Exercise may differently affect the expression of key molecular markers, including skeletal muscle and circulating miRNAs, involved in cellular and metabolic pathways’ regulation in healthy individuals and in patients suffering from non-communicabl
Externí odkaz:
https://doaj.org/article/642d82d9085249579628f8660251e91c
Autor:
Pierfrancesco Tassone, Maria Teresa Di Martino, Mariamena Arbitrio, Lucia Fiorillo, Nicoletta Staropoli, Domenico Ciliberto, Alessia Cordua, Francesca Scionti, Bernardo Bertucci, Angela Salvino, Mariangela Lopreiato, Fredrik Thunarf, Onofrio Cuomo, Maria Cristina Zito, Maria Rosanna De Fina, Amelia Brescia, Simona Gualtieri, Caterina Riillo, Francesco Manti, Daniele Caracciolo, Vito Barbieri, Eugenio Donato Di Paola, Adele Emanuela Di Francesco, Pierosandro Tagliaferri
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Background We developed a 13-mer locked nucleic acid (LNA) inhibitor of miR-221 (LNA-i-miR-221) with a full phosphorothioate (PS)-modified backbone. This agent downregulated miR-221, demonstrated anti-tumor activity against human xenografts
Externí odkaz:
https://doaj.org/article/4d9a753abc2e49c2bbde30064f04d177
Autor:
Francesca Scionti, Giada Juli, Roberta Rocca, Nicoletta Polerà, Matteo Nadai, Katia Grillone, Daniele Caracciolo, Caterina Riillo, Emanuela Altomare, Serena Ascrizzi, Basilio Caparello, Maria Cerra, Mariamena Arbitrio, Sara N. Richter, Anna Artese, Stefano Alcaro, Pierosandro Tagliaferri, Pierfrancesco Tassone, Maria Teresa Di Martino
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-15 (2023)
Abstract Background Multiple myeloma (MM) is a hematologic malignancy characterized by high genomic instability, and telomere dysfunction is an important cause of acquired genomic alterations. Telomeric repeat-containing RNA (TERRA) transcripts are l
Externí odkaz:
https://doaj.org/article/657b2ace4408422d945e128b38b6e06e
Autor:
Lydia Giannitrapani, Francesca Di Gaudio, Melchiorre Cervello, Francesca Scionti, Domenico Ciliberto, Nicoletta Staropoli, Giuseppe Agapito, Mario Cannataro, Pierfrancesco Tassone, Pierosandro Tagliaferri, Aurelio Seidita, Maurizio Soresi, Marco Affronti, Gaetano Bertino, Maurizio Russello, Rosaria Ciriminna, Claudia Lino, Francesca Spinnato, Francesco Verderame, Giuseppa Augello, Mariamena Arbitrio
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2197 (2024)
The identification of biomarkers for predicting inter-individual sorafenib response variability could allow hepatocellular carcinoma (HCC) patient stratification. SNPs in angiogenesis- and drug absorption, distribution, metabolism, and excretion (ADM
Externí odkaz:
https://doaj.org/article/c4832868412d4f2cb39e68045655c849
Autor:
Daniele Caracciolo, Giada Juli, Caterina Riillo, Adriana Coricello, Francesca Vasile, Sara Pollastri, Roberta Rocca, Francesca Scionti, Nicoletta Polerà, Katia Grillone, Mariamena Arbitrio, Nicoletta Staropoli, Basilio Caparello, Domenico Britti, Giovanni Loprete, Giosuè Costa, Maria Teresa Di Martino, Stefano Alcaro, Pierosandro Tagliaferri, Pierfrancesco Tassone
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Background DNA ligases are crucial for DNA repair and cell replication since they catalyze the final steps in which DNA breaks are joined. DNA Ligase III (LIG3) exerts a pivotal role in Alternative-Non-Homologous End Joining Repair (Alt-NHEJ
Externí odkaz:
https://doaj.org/article/20987083a587406d8c182098d47e70c9
Autor:
Maria Eugenia Gallo Cantafio, Roberta Torcasio, Francesca Scionti, Maria Mesuraca, Domenica Ronchetti, Mariaelena Pistoni, Dina Bellizzi, Giuseppe Passarino, Eugenio Morelli, Antonino Neri, Giuseppe Viglietto, Nicola Amodio
Publikováno v:
Cells, Vol 12, Iss 18, p 2226 (2023)
G protein-coupled estrogen receptor 1 (GPER1) activation is emerging as a promising therapeutic strategy against several cancer types. While GPER targeting has been widely studied in the context of solid tumors, its effect on hematological malignanci
Externí odkaz:
https://doaj.org/article/44fb7133e83a428aa1df95e90927d55a
Autor:
Maria Teresa Di Martino, Mariamena Arbitrio, Daniele Caracciolo, Alessia Cordua, Onofrio Cuomo, Katia Grillone, Caterina Riillo, Giulio Caridà, Francesca Scionti, Caterina Labanca, Caterina Romeo, Maria Anna Siciliano, Maria D'Apolito, Cristina Napoli, Martina Montesano, Valentina Farenza, Valentina Uppolo, Michele Tafuni, Federica Falcone, Giuseppe D'Aquino, Natale Daniele Calandruccio, Francesco Luciano, Licia Pensabene, Pierosandro Tagliaferri, Pierfrancesco Tassone
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 1191-1224 (2022)
Among deregulated microRNAs (miRs) in human malignancies, miR-221 has been widely investigated for its oncogenic role and as a promising biomarker. Moreover, recent evidence suggests miR-221 as a fine-tuner of chronic liver injury and inflammation-re
Externí odkaz:
https://doaj.org/article/3c736b7269e24e3894170eed8e9340d9
Autor:
Cristina Barbagallo, Michele Stella, Stefania Di Mauro, Alessandra Scamporrino, Agnese Filippello, Francesca Scionti, Maria Teresa Di Martino, Michele Purrello, Marco Ragusa, Francesco Purrello, Salvatore Piro
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13485 (2023)
Diabetes mellitus (DM) is a complex and multifactorial disease characterised by high blood glucose. Type 2 Diabetes (T2D), the most frequent clinical condition accounting for about 90% of all DM cases worldwide, is a chronic disease with slow develop
Externí odkaz:
https://doaj.org/article/7d66fdddf56945e289184e3bff0a7bf3