Výsledky vyhledávání - "Francesca Scavo"

Akademický článek

Inhibition of MMPs supports amoeboid angiogenesis hampering VEGF-targeted therapies via MLC and ERK 1/2 signaling

Autor: Anastasia Chillà, Cecilia Anceschi, Elena Frediani, Francesca Scavone, Tommaso Del Rosso, Giuseppe Pelagio, Antonio Tufaro, Giuseppe De Palma, Mario Del Rosso, Gabriella Fibbi, Paola Chiarugi, Anna Laurenzana, Francesca Margheri

Publikováno v: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)

Abstract Background In the past decades studies on anti-tumoral drugs inhibiting matrix metalloproteinase (MMPs) were disappointing. Recently, we demonstrated that mature endothelial cells (ECs) and endothelial colony forming cells (ECFCs) can switch

Externí odkaz: https://doaj.org/article/3931730896874b4891dffd1dbb7f2d52

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Akademický článek

Proton Therapy, Magnetic Nanoparticles and Hyperthermia as Combined Treatment for Pancreatic BxPC3 Tumor Cells

Publikováno v: Nanomaterials, Vol 13, Iss 5, p 791 (2023)

We present an investigation of the effects on BxPC3 pancreatic cancer cells of proton therapy combined with hyperthermia, assisted by magnetic fluid hyperthermia performed with the use of magnetic nanoparticles. The cells’ response to the combined

Externí odkaz: https://doaj.org/article/e7cc51f6543f4d8fb957f02a0ab1cb4c

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Akademický článek

CRISPR/Cas9 uPAR Gene Knockout Results in Tumor Growth Inhibition, EGFR Downregulation and Induction of Stemness Markers in Melanoma and Colon Carcinoma Cell Lines

Autor: Alessio Biagioni, Anastasia Chillà, Mario Del Rosso, Gabriella Fibbi, Francesca Scavone, Elena Andreucci, Silvia Peppicelli, Francesca Bianchini, Lido Calorini, Anna Li Santi, Pia Ragno, Francesca Margheri, Anna Laurenzana

Publikováno v: Frontiers in Oncology, Vol 11 (2021)

uPAR is a globular protein, tethered to the cell membrane by a GPI-anchor involved in several cancer-related properties and its overexpression commonly correlates with poor prognosis and metastasis. We investigated the consequences of uPAR irreversib

Externí odkaz: https://doaj.org/article/20a77ee24da847da832d2ea4fc6f241a

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Akademický článek

The 'End Life' of the Grape Pomace Waste Become the New Beginning: The Development of a Virtuous Cycle for the Green Synthesis of Gold Nanoparticles and Removal of Emerging Contaminants from Water

Autor: Jennifer Gubitosa, Vito Rizzi, Anna Laurenzana, Francesca Scavone, Elena Frediani, Gabriella Fibbi, Fiorenza Fanelli, Teresa Sibillano, Cinzia Giannini, Paola Fini, Pinalysa Cosma

Publikováno v: Antioxidants, Vol 11, Iss 5, p 994 (2022)

During the last decades, the demand for processes developed according to the Circular Economy Principles has increased, searching for an alternative life for wastes. For this purpose, a one-pot green approach is exploited during this work to synthesi

Externí odkaz: https://doaj.org/article/5e492a825779479098540197c6084cc5

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Akademický článek

Smart Magnetic Nanocarriers for Multi-Stimuli On-Demand Drug Delivery

Autor: Parisa Eslami, Martin Albino, Francesca Scavone, Federica Chiellini, Andrea Morelli, Giovanni Baldi, Laura Cappiello, Saer Doumett, Giada Lorenzi, Costanza Ravagli, Andrea Caneschi, Anna Laurenzana, Claudio Sangregorio

Publikováno v: Nanomaterials, Vol 12, Iss 3, p 303 (2022)

In this study, we report the realization of drug-loaded smart magnetic nanocarriers constituted by superparamagnetic iron oxide nanoparticles encapsulated in a dual pH- and temperature-responsive poly (N-vinylcaprolactam-co-acrylic acid) copolymer to

Externí odkaz: https://doaj.org/article/f1ce6ab21f274026974ef5f40abcd6f6

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