Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Francesca Sardina"'
Autor:
Francesca Sardina, Laura Monteonofrio, Manuela Ferrara, Fiorenza Magi, Silvia Soddu, Cinzia Rinaldo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
At the end of abscission, the residual midbody forms the so-called midbody remnant (MBR), a platform affecting cell fate with emerging key role in differentiation, development, and tumorigenicity. Depending on cell type and pathophysiological context
Externí odkaz:
https://doaj.org/article/3148df0f8669481b914178f4252ca130
Autor:
Alessandra Pisciottani, Loredana Biancolillo, Manuela Ferrara, Davide Valente, Francesca Sardina, Laura Monteonofrio, Serena Camerini, Marco Crescenzi, Silvia Soddu, Cinzia Rinaldo
Publikováno v:
Cells, Vol 8, Iss 7, p 684 (2019)
Abscission is the final step of cell division, mediating the physical separation of the two daughter cells. A key player in this process is the microtubule-severing enzyme spastin that localizes at the midbody where its activity is crucial to cut mic
Externí odkaz:
https://doaj.org/article/6531ac2d6bdd465fbaf46d6702cd73a1
Autor:
Francesca Sardina, Davide Valente, Gaia Fattorini, Ettore Cioffi, Gianmarco Dalla Zanna, Alessandra Tessa, Daniela Trisciuoglio, Silvia Soddu, Filippo M. Santorelli, Carlo Casali, Cinzia Rinaldo
Publikováno v:
European Journal of Neurology. 30:1734-1744
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dd25c2b369d92319c370ed9117945d8
https://doi.org/10.1111/ene.15756
https://doi.org/10.1111/ene.15756
Autor:
Davide Valente, Cinzia Rinaldo, Alessandra Pisciottani, Carlo Casali, Francesca Sardina, Manuela Ferrara, Marco Crescenzi, Andrew J. Grierson, Silvia Soddu, Angelo Peschiaroli, Marialuisa Casella
Publikováno v:
Life Science Alliance
The balance between HIPK2-mediated phosphorylation and neddylation-dependent degradation controls spastin protein levels, revealing novel therapeutic targets for hereditary spastic paraplegia.
Hereditary Spastic Paraplegia (HSP) is a neurodegene
Hereditary Spastic Paraplegia (HSP) is a neurodegene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133a54fc2e4c5ac62fdd4f9c04db4361
https://eprints.whiterose.ac.uk/167965/1/e202000799.full.pdf
https://eprints.whiterose.ac.uk/167965/1/e202000799.full.pdf
Autor:
Maria Giubettini, Marta Moretti, Gianluca Canettieri, Flaminia Pedretti, Giuseppe Giannini, Marialaura Petroni, Beatrice Cardinali, Paola Infante, Stefano Di Giulio, Alessandro Corsi, Simone De Panfilis, Francesca Belardinilli, Valentina Ramponi, Maria Sahùn Roncero, Vittoria Nicolis di Robilant, Enrico De Smaele, Carlo Capalbo, Vincenzo Alfano, Francesca Fabretti, Valeria Colicchia, Alessandra Tessitore, Francesca Sardina, Anna Coppa
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Growth and patterning of the cerebellum is compromised if granule cell precursors do not properly expand and migrate. During embryonic and postnatal cerebellar development, the Hedgehog pathway tightly regulates granule cell progenitors to coordinate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64483e2655b64cd75803fb9f383c397d
https://doi.org/10.1038/s41598-019-56057-y
https://doi.org/10.1038/s41598-019-56057-y
Autor:
Davide Valente, Cinzia Rinaldo, Alessandra Pisciottani, Marco Crescenzi, Loredana Biancolillo, Manuela Ferrara, Serena Camerini, Laura Monteonofrio, Silvia Soddu, Francesca Sardina
Publikováno v:
Cells, Vol 8, Iss 7, p 684 (2019)
Cells 8 (2019). doi:10.3390/cells8070684
info:cnr-pdr/source/autori:Pisciottani, Alessandra; Biancolillo, Loredana; Ferrara, Manuela; Valente, Davide; Sardina, Francesca; Monteonofrio, Laura; Camerini, Serena; Crescenzi, Marco; Soddu, Silvia; Rinaldo, Cinzia/titolo:HIPK2 Phosphorylates the Microtubule-Severing Enzyme Spastin at S268 for Abscission/doi:10.3390%2Fcells8070684/rivista:Cells/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Cells
Volume 8
Issue 7
Cells 8 (2019). doi:10.3390/cells8070684
info:cnr-pdr/source/autori:Pisciottani, Alessandra; Biancolillo, Loredana; Ferrara, Manuela; Valente, Davide; Sardina, Francesca; Monteonofrio, Laura; Camerini, Serena; Crescenzi, Marco; Soddu, Silvia; Rinaldo, Cinzia/titolo:HIPK2 Phosphorylates the Microtubule-Severing Enzyme Spastin at S268 for Abscission/doi:10.3390%2Fcells8070684/rivista:Cells/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Cells
Volume 8
Issue 7
Abscission is the final step of cell division, mediating the physical separation of the two daughter cells. A key player in this process is the microtubule-severing enzyme spastin that localizes at the midbody where its activity is crucial to cut mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88ca65db1984abc11791a5445b68695
https://www.mdpi.com/2073-4409/8/7/684
https://www.mdpi.com/2073-4409/8/7/684
Autor:
Lucia Di Marcotullio, Armando Bartolazzi, Stefano Di Giulio, Marialaura Petroni, Maria Sahùn Roncero, Francesca Belardinilli, Francesca Sardina, Carlo Capalbo, Anna Coppa, Giuseppe Giannini, Beatrice Cardinali, Francesca Fabretti, Paola Infante, Mauro Comes Franchini, Silvia Soddu, Alberto Gulino, Valeria Colicchia, Alessandra Tessitore, Erica Locatelli, Elena Petricci
Publikováno v:
Cell Death and Disease, Vol 9, Iss 9, Pp 1-12 (2018)
Cell Death & Disease
Cell death and disease 9 (2018). doi:10.1038/s41419-018-0924-z
info:cnr-pdr/source/autori:Petroni M.; Sardina F.; Infante P.; Bartolazzi A.; Locatelli E.; Fabretti F.; Di Giulio S.; Capalbo C.; Cardinali B.; Coppa A.; Tessitore A.; Colicchia V.; Sahun Roncero M.; Belardinilli F.; Di Marcotullio L.; Soddu S.; Comes Franchini M.; Petricci E.; Gulino A.; Giannini G./titolo:MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors/doi:10.1038%2Fs41419-018-0924-z/rivista:Cell death and disease/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Cell Death & Disease
Cell death and disease 9 (2018). doi:10.1038/s41419-018-0924-z
info:cnr-pdr/source/autori:Petroni M.; Sardina F.; Infante P.; Bartolazzi A.; Locatelli E.; Fabretti F.; Di Giulio S.; Capalbo C.; Cardinali B.; Coppa A.; Tessitore A.; Colicchia V.; Sahun Roncero M.; Belardinilli F.; Di Marcotullio L.; Soddu S.; Comes Franchini M.; Petricci E.; Gulino A.; Giannini G./titolo:MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors/doi:10.1038%2Fs41419-018-0924-z/rivista:Cell death and disease/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
MRE11 is a component of the MRE11/RAD50/NBS1 (MRN) complex, whose activity is essential to control faithful DNA replication and to prevent accumulation of deleterious DNA double-strand breaks. In humans, hypomorphic mutations in these genes lead to D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43adb64dd7903753b52d1fee1524d41f
http://hdl.handle.net/11585/654243
http://hdl.handle.net/11585/654243
Autor:
Veronica Veschi, Alberto Gulino, Valeria Colicchia, L Di Marcotullio, Giuseppe Giannini, Biancamaria Ricci, M Sahún-Roncero, Isabella Screpanti, Sonia Albini, C Heil, Francesca Sardina, Marialaura Petroni, Alessandra Soriani, Doriana Fruci
Publikováno v:
Cell Death and Differentiation
The MRE11/RAD50/NBS1 (MRN) complex is a major sensor of DNA double strand breaks, whose role in controlling faithful DNA replication and preventing replication stress is also emerging. Inactivation of the MRN complex invariably leads to developmental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7682215f720d9f60d9ae095b4b1f0c
http://europepmc.org/articles/PMC4716299
http://europepmc.org/articles/PMC4716299
Autor:
Francesca Sardina, Paola Infante, M. Comes-Franchini, Giuseppe Giannini, Elena Petricci, C Heil, Erica Locatelli, M. Sahùn Roncero, Biancamaria Ricci, Marialaura Petroni
Publikováno v:
European Journal of Cancer. 61:S135-S136
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7c4da39e7d0f727b0d23d7957ccf6b6
https://doi.org/10.1016/s0959-8049(16)61479-x
https://doi.org/10.1016/s0959-8049(16)61479-x
Autor:
Giuseppe Montalto, James A. McCubrey, Lydia Giannitrapani, Antonella Cusimano, Melchiorre Cervello, Nadia Lampiasi, Dimcho Bachvarov, Francesca Sardina, Antonina Azzolina
Publikováno v:
Omics : a journal of integrative biology. 15(6)
Celecoxib (Celebrex((R)), Pfizer) is a selective cyclooxygenase-2 (COX-2) inhibitor with chemopreventive and antitumor effects. However, it is now well known that celecoxib has several COX-2-independent activities. To better understand COX-2-independ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f436daeb827142639ae39a5e4146069
https://pubmed.ncbi.nlm.nih.gov/21410330
https://pubmed.ncbi.nlm.nih.gov/21410330