Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Francesca Ros"'
Autor:
Szabolcs Éliás, Clemens Wrzodek, Charlotte M. Deane, Alain C. Tissot, Stefan Klostermann, Francesca Ros
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2024)
Antibodies are generated with great diversity in nature resulting in a set of molecules, each optimized to bind a specific target. Taking advantage of their diversity and specificity, antibodies make up for a large part of recently developed biologic
Externí odkaz:
https://doaj.org/article/82c207e452cf49e4b1f72cfe95d982e4
Autor:
Francesca Ros, Sonja Offner, Stefan Klostermann, Irmgard Thorey, Helmut Niersbach, Sebastian Breuer, Grit Zarnt, Stefan Lorenz, Juergen Puels, Basile Siewe, Nicole Schueler, Tajana Dragicevic, Dominique Ostler, Imke Hansen-Wester, Valeria Lifke, Brigitte Kaluza, Klaus Kaluza, Wim van Schooten, Roland Buelow, Alain C Tissot, Josef Platzer
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Transgenic animals incorporating human antibody genes are extremely attractive for drug development because they obviate subsequent antibody humanization procedures required for therapeutic translation. Transgenic platforms have previously been estab
Externí odkaz:
https://doaj.org/article/eb4cfd37c8a244a096d64b9303c73a7f
Autor:
Stefan Seeber, Francesca Ros, Irmgard Thorey, Georg Tiefenthaler, Klaus Kaluza, Valeria Lifke, Jens André Alexander Fischer, Stefan Klostermann, Josef Endl, Erhard Kopetzki, Achal Pashine, Basile Siewe, Brigitte Kaluza, Josef Platzer, Sonja Offner
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86184 (2014)
We have developed a robust platform to generate and functionally characterize rabbit-derived antibodies using B cells from peripheral blood. The rapid high throughput procedure generates a diverse set of antibodies, yet requires only few animals to b
Externí odkaz:
https://doaj.org/article/121e8ae00e8c4eaa9913c08d88a77bdd
Autor:
Tatiana Flisikowska, Irmgard S Thorey, Sonja Offner, Francesca Ros, Valeria Lifke, Bryan Zeitler, Oswald Rottmann, Anna Vincent, Lei Zhang, Shirin Jenkins, Helmut Niersbach, Alexander J Kind, Philip D Gregory, Angelika E Schnieke, Josef Platzer
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21045 (2011)
Rabbits are widely used in biomedical research, yet techniques for their precise genetic modification are lacking. We demonstrate that zinc finger nucleases (ZFNs) introduced into fertilized oocytes can inactivate a chosen gene by mutagenesis and als
Externí odkaz:
https://doaj.org/article/28865b2f7cbb4665ba7b4622b6f2e4fd
Autor:
Alice Grossi, Francesca Rosamilia, Silvia Carestiato, Ettore Salsano, Isabella Ceccherini, Tiziana Bachetti
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Alexander disease (ALXDRD) is a rare neurodegenerative disorder of astrocytes resulting from pathogenic variants in the GFAP gene. The genotype-phenotype correlation remains elusive due to the variable expressivity of clinical manifestations
Externí odkaz:
https://doaj.org/article/a1c0b5bdba1c49318f81f15a964c9991
Autor:
Francesca Rossi, Monica Valle, Giovanni Galeoto, Marco Tofani, Paola Berchialla, Veronica Sciannameo, Daniele Bertin, Annalisa Calcagno, Roberto Casalaz, Margherita Cerboneschi, Marta Cervo, Annalisa Cornelli, Chiara Di Pede, Maria Esposito, Miriana Ferrarese, Paola Imazio, Maria Lorenzon, Lucia Longo, Andrea Martinuzzi, Gabriella Naretto, Nicoletta Orsini, Daniele Panzeri, Chiara Pellegrini, Michela Peranzoni, Fabiola Picone, Marco Rabusin, Federica Ricci, Claudia Zigrino, Giulia Zucchetti, Franca Fagioli
Publikováno v:
Current Oncology, Vol 31, Iss 9, Pp 5291-5306 (2024)
Children/adolescents with cancer can develop adverse effects impacting gross motor function. There is a lack of gross motor function assessment tools that have been validated for this population. The aim of this multicenter cross-sectional study was
Externí odkaz:
https://doaj.org/article/bc9a726774e74131bc0c032ae3f90b8c
Autor:
Przemyslaw Rzepka, Matteo Signorile, Thomas Huthwelker, Stefano Checchia, Francesca Rosso, Silvia Bordiga, Jeroen A. van Bokhoven
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract One of the biggest obstacles to developing better zeolite-based catalysts is the lack of methods for quantitatively locating light heteroatoms on the T-sites in zeolites. Titanium silicalite-1 (TS-1) is a Ti-bearing zeolite-type catalyst com
Externí odkaz:
https://doaj.org/article/b74626b82bd64f619ffa3e3037fb1a8a
Autor:
Benedetta Ghezzi, Biagio Matera, Matteo Meglioli, Francesca Rossi, Donatella Duraccio, Maria Giulia Faga, Andrea Zappettini, Guido Maria Macaluso, Simone Lumetti
Publikováno v:
International Dental Journal, Vol 74, Iss 6, Pp 1220-1232 (2024)
ABSTRACT: Objectives: The purpose of this work was to optimise printable polycaprolactone (PCL)/β-tricalcium phosphate (β-TCP) biomaterials with high percentages of β-TCP endowed with balanced mechanical characteristics to resemble human cancellou
Externí odkaz:
https://doaj.org/article/e247fcd93f5944ecb925ebd720a4442e
Autor:
Nicola Mosca, Nicola Alessio, Alessandra Di Paola, Maria Maddalena Marrapodi, Umberto Galderisi, Aniello Russo, Francesca Rossi, Nicoletta Potenza
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-30 (2024)
Abstract Osteosarcoma (OS) is the most prevalent and fatal type of bone tumor. It is characterized by great heterogeneity of genomic aberrations, mutated genes, and cell types contribution, making therapy and patients management particularly challeng
Externí odkaz:
https://doaj.org/article/f251f75b256245dab5fa59d955de08a2
Autor:
Benedetta Ghezzi, Matteo Meglioli, Andrea Salvaterra Toffoli, Giovanni Mergoni, Francesca Rossi, Maddalena Manfredi, Simone Lumetti, Edoardo Manfredi
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Carious/Non-carious cervical lesions with gingival recessions may require both dental and periodontal reconstructive therapy, where flaps/grafts may be placed in contact with a dental filling material. Human Gingival Fibroblasts (
Externí odkaz:
https://doaj.org/article/d731ff2c3fda4e67b73c9c86809d29c4