Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Francesca Ros"'
Autor:
Szabolcs Éliás, Clemens Wrzodek, Charlotte M. Deane, Alain C. Tissot, Stefan Klostermann, Francesca Ros
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2024)
Antibodies are generated with great diversity in nature resulting in a set of molecules, each optimized to bind a specific target. Taking advantage of their diversity and specificity, antibodies make up for a large part of recently developed biologic
Externí odkaz:
https://doaj.org/article/82c207e452cf49e4b1f72cfe95d982e4
Autor:
Francesca Ros, Sonja Offner, Stefan Klostermann, Irmgard Thorey, Helmut Niersbach, Sebastian Breuer, Grit Zarnt, Stefan Lorenz, Juergen Puels, Basile Siewe, Nicole Schueler, Tajana Dragicevic, Dominique Ostler, Imke Hansen-Wester, Valeria Lifke, Brigitte Kaluza, Klaus Kaluza, Wim van Schooten, Roland Buelow, Alain C Tissot, Josef Platzer
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Transgenic animals incorporating human antibody genes are extremely attractive for drug development because they obviate subsequent antibody humanization procedures required for therapeutic translation. Transgenic platforms have previously been estab
Externí odkaz:
https://doaj.org/article/eb4cfd37c8a244a096d64b9303c73a7f
Autor:
Stefan Seeber, Francesca Ros, Irmgard Thorey, Georg Tiefenthaler, Klaus Kaluza, Valeria Lifke, Jens André Alexander Fischer, Stefan Klostermann, Josef Endl, Erhard Kopetzki, Achal Pashine, Basile Siewe, Brigitte Kaluza, Josef Platzer, Sonja Offner
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86184 (2014)
We have developed a robust platform to generate and functionally characterize rabbit-derived antibodies using B cells from peripheral blood. The rapid high throughput procedure generates a diverse set of antibodies, yet requires only few animals to b
Externí odkaz:
https://doaj.org/article/121e8ae00e8c4eaa9913c08d88a77bdd
Autor:
Tatiana Flisikowska, Irmgard S Thorey, Sonja Offner, Francesca Ros, Valeria Lifke, Bryan Zeitler, Oswald Rottmann, Anna Vincent, Lei Zhang, Shirin Jenkins, Helmut Niersbach, Alexander J Kind, Philip D Gregory, Angelika E Schnieke, Josef Platzer
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21045 (2011)
Rabbits are widely used in biomedical research, yet techniques for their precise genetic modification are lacking. We demonstrate that zinc finger nucleases (ZFNs) introduced into fertilized oocytes can inactivate a chosen gene by mutagenesis and als
Externí odkaz:
https://doaj.org/article/28865b2f7cbb4665ba7b4622b6f2e4fd
Autor:
Przemyslaw Rzepka, Matteo Signorile, Thomas Huthwelker, Stefano Checchia, Francesca Rosso, Silvia Bordiga, Jeroen A. van Bokhoven
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract One of the biggest obstacles to developing better zeolite-based catalysts is the lack of methods for quantitatively locating light heteroatoms on the T-sites in zeolites. Titanium silicalite-1 (TS-1) is a Ti-bearing zeolite-type catalyst com
Externí odkaz:
https://doaj.org/article/b74626b82bd64f619ffa3e3037fb1a8a
Autor:
Nicola Mosca, Nicola Alessio, Alessandra Di Paola, Maria Maddalena Marrapodi, Umberto Galderisi, Aniello Russo, Francesca Rossi, Nicoletta Potenza
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-30 (2024)
Abstract Osteosarcoma (OS) is the most prevalent and fatal type of bone tumor. It is characterized by great heterogeneity of genomic aberrations, mutated genes, and cell types contribution, making therapy and patients management particularly challeng
Externí odkaz:
https://doaj.org/article/f251f75b256245dab5fa59d955de08a2
Autor:
Benedetta Ghezzi, Matteo Meglioli, Andrea Salvaterra Toffoli, Giovanni Mergoni, Francesca Rossi, Maddalena Manfredi, Simone Lumetti, Edoardo Manfredi
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Carious/Non-carious cervical lesions with gingival recessions may require both dental and periodontal reconstructive therapy, where flaps/grafts may be placed in contact with a dental filling material. Human Gingival Fibroblasts (
Externí odkaz:
https://doaj.org/article/d731ff2c3fda4e67b73c9c86809d29c4
Autor:
Lina Mtwana Nordlund, Richard K. F. Unsworth, Sieglind Wallner‐Hahn, Lavenia Ratnarajah, Pedro Beca‐Carretero, Elmira Boikova, James C. Bull, Rosa M. Chefaoui, Carmen B. de losSantos, Karine Gagnon, Joxe Mikel Garmendia, Francesca Gizzi, Laura L. Govers, Camilla Gustafsson, Elitsa Hineva, Eduardo Infantes, João Canning‐Clode, Marlene Jahnke, Periklis Kleitou, Hilary Kennedy, Stefania Klayn, Tiia Moller, João Monteiro, Nerea Piñeiro‐Juncal, Emanuele Ponis, Vasillis Papathanasiou, Dimitris Poursanidis, Riccardo Pieraccini, Oscar Serrano, Ana. I. Sousa, Susanne Schäfer, Francesca Rossi, D. Sebastian Storey, Marieke M. vanKatwijk, Dave Wall, Emma A. Ward, Robert Wilkes
Publikováno v:
Plants, People, Planet, Vol 6, Iss 3, Pp 587-603 (2024)
Societal Impact Statement Seagrass ecosystems are of fundamental importance to our planet and wellbeing. Seagrasses are marine flowering plants, which engineer ecosystems that provide a multitude of ecosystem services, for example, blue foods and car
Externí odkaz:
https://doaj.org/article/c2f4e9ce38a146768ced7b09d3af001e
Autor:
Francesco Crescenzo, Mattia Zanoni, Laura Ferigo, Francesca Rossi, Matteo Grecò, Angelica Lupato, Alessandra Danese, Domenico Ajena, Michelangelo Turazzini
Publikováno v:
Muscles, Vol 3, Iss 1, Pp 40-47 (2024)
Eculizumab is a monoclonal antibody blocking the terminal complement protein C5. As demonstrated in the phase III randomized, placebo-controlled, REGAIN clinical trial, eculizumab is efficacious in acetylcholine receptor antibody (AChR-Ab)-positive r
Externí odkaz:
https://doaj.org/article/9c89395f93184f699ca7e7b207045c09
Publikováno v:
Global Ecology and Conservation, Vol 51, Iss , Pp e02875- (2024)
The non-breeding distribution and ecology of many migratory songbirds are often poorly studied, but very relevant for their conservation in a changing climate. The Snow Bunting is the most northerly breeding passerine worldwide, and winters in temper
Externí odkaz:
https://doaj.org/article/9c792001ceff4910bd3472f970b45202