Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Francesca Romana Liberati"'
Autor:
Ritwik Maity, Xuepei Zhang, Francesca Romana Liberati, Chiara Scribani Rossi, Francesca Cutruzzolá, Serena Rinaldo, Massimiliano Gaetani, José Antonio Aínsa, Javier Sancho
Publikováno v:
eLife, Vol 13 (2024)
Antimicrobial resistance is responsible for an alarming number of deaths, estimated at 5 million per year. To combat priority pathogens, like Helicobacter pylori, the development of novel therapies is of utmost importance. Understanding the molecular
Externí odkaz:
https://doaj.org/article/8e9d33b85838437486c00c392fcb85a6
Autor:
Sara Di Russo, Francesca Romana Liberati, Agnese Riva, Federica Di Fonzo, Alberto Macone, Giorgio Giardina, Marzia Arese, Serena Rinaldo, Francesca Cutruzzolà, Alessio Paone
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Extravasation is a fundamental step in the metastatic journey, where cancer cells exit the bloodstream and breach the endothelial cell barrier to infiltrate target tissues. The tactics cancer cells employ are sophisticated, closely reflectin
Externí odkaz:
https://doaj.org/article/6955f71b5f474395bbadf1663f02dbc8
Autor:
Francesca Romana Liberati, Sara Di Russo, Lorenzo Barolo, Giovanna Peruzzi, Maria Vittoria Farina, Sharon Spizzichino, Federica Di Fonzo, Deborah Quaglio, Luca Pisano, Bruno Botta, Alessandra Giorgi, Alberto Boffi, Francesca Cutruzzolà, Alessio Paone, Paola Baiocco
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 402 (2024)
Chronic lymphocytic leukemia (CLL) is a widespread type of leukemia that predominantly targets B lymphocytes, undermining the balance between cell proliferation and apoptosis. In healthy B cells, miR-15/16, a tandem of microRNAs, functions as a tumor
Externí odkaz:
https://doaj.org/article/c3cb26ae36b04029a7e08117175fdbb3
Autor:
Michele Monti, Giulia Guiducci, Alessio Paone, Serena Rinaldo, Giorgio Giardina, Francesca Romana Liberati, Francesca Cutruzzolá, Gian Gaetano Tartaglia
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3034-3041 (2021)
Human serine hydroxymethyltransferase (SHMT) regulates the serine-glycine one carbon metabolism and plays a role in cancer metabolic reprogramming. Two SHMT isozymes are acting in the cell: SHMT1 encoding the cytoplasmic isozyme, and SHMT2 encoding t
Externí odkaz:
https://doaj.org/article/e77dbfb8823f40ff9b0b3faaad8e171c
Autor:
Amani Bouzidi, Maria Chiara Magnifico, Alessandro Paiardini, Alberto Macone, Giovanna Boumis, Giorgio Giardina, Serena Rinaldo, Francesca Romana Liberati, Clotilde Lauro, Cristina Limatola, Chiara Lanzillotta, Antonella Tramutola, Marzia Perluigi, Gianluca Sgarbi, Giancarlo Solaini, Alessandra Baracca, Alessio Paone, Francesca Cutruzzolà
Publikováno v:
Cell Death and Disease, Vol 11, Iss 11, Pp 1-14 (2020)
Lung cancer is a very aggressive tumor that often forms brain metastases. We show that lung cancer cells motility, fundamental for the formation of metastases, is controlled by amino acids such as serine and glycine, abundant in brain microenvironmen
Externí odkaz:
https://doaj.org/article/4fc13ba560544c24b6d2c73b34ca5f0d
Autor:
Sharon Spizzichino, Federica Di Fonzo, Chiara Marabelli, Angela Tramonti, Antonio Chaves-Sanjuan, Alessia Parroni, Giovanna Boumis, Francesca Romana Liberati, Alessio Paone, Linda Celeste Montemiglio, Matteo Ardini, Arjen J. Jakobi, Alok Bharadwaj, Paolo Swuec, Gian Gaetano Tartaglia, Alessandro Paiardini, Roberto Contestabile, Serena Rinaldo, Martino Bolognesi, Giorgio Giardina, Francesca Cutruzzolà
SUMMARYRNA can directly control protein activity in a process called riboregulation; only a few mechanisms of riboregulation have been described in detail, none of these being characterized on structural grounds. Here we present a comprehensive struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f9f52133ee2417e922af975fd32e89a
https://doi.org/10.1101/2023.03.17.532973
https://doi.org/10.1101/2023.03.17.532973
Autor:
Marianna Bufano, Michela Puxeddu, Marianna Nalli, Giuseppe La Regina, Angelo Toto, Francesca Romana Liberati, Alessio Paone, Francesca Cutruzzolà, Domiziana Masci, Chiara Bigogno, Giulio Dondio, Romano Silvestri, Stefano Gianni, Antonio Coluccia
Publikováno v:
Bioorganic Chemistry. 138:106607
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afec4cc73e2a1397ba1631af84ee4a84
https://doi.org/10.1016/j.bioorg.2023.106607
https://doi.org/10.1016/j.bioorg.2023.106607
Autor:
Francesca Romana Liberati, Roberta Piacentini, Alessandro Paiardini, Angela Tramonti, Giorgio Giardina, Roberta Lucchi, Serena Rinaldo, Giorgio Pochetti, Roberto Contestabile, Giacomo Parisi, Sharon Spizzichino, Dalila Boi, Francesca Cutruzzolà, Giovanna Boumis, Davide Capelli, Alessio Paone, Roberta Montanari
Publikováno v:
The FEBS journal (Online) (2021).
info:cnr-pdr/source/autori:Sharon Spizzichino, Dalila Boi, Giovanna Boumis, Roberta Lucchi, Francesca Romana Liberati, Davide Capelli, Roberta Montanari, Giorgio Pochetti, Roberta Piacentini, Giacomo Parisi, Alessio Paone, Serena Rinaldo, Roberto Contestabile, Alessandro Paiardini, Angela Tramonti, Giorgio Giardina, Francesca Cutruzzolà/titolo:Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex/doi:/rivista:The FEBS journal (Online)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume
The FEBS journal
(2021). doi:10.1111/febs.16248
info:cnr-pdr/source/autori:Spizzichino, Sharon; Boi, Dalila; Boumis, Giovanna; Lucchi, Roberta; Liberati, Francesca Romana; Capelli, Davide; Montanari, Roberta; Pochetti, Giorgio; Piacentini, Roberta; Parisi, Giacomo; Paone, Alessio; Rinaldo, Serena; Contestabile, Roberto; Tramonti, Angela; Paiardini, Alessandro; Giardina, Giorgio; Cutruzzolà, Francesca/titolo:Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex/doi:10.1111%2Ffebs.16248/rivista:The FEBS journal (Print)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume
info:cnr-pdr/source/autori:Sharon Spizzichino, Dalila Boi, Giovanna Boumis, Roberta Lucchi, Francesca Romana Liberati, Davide Capelli, Roberta Montanari, Giorgio Pochetti, Roberta Piacentini, Giacomo Parisi, Alessio Paone, Serena Rinaldo, Roberto Contestabile, Alessandro Paiardini, Angela Tramonti, Giorgio Giardina, Francesca Cutruzzolà/titolo:Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex/doi:/rivista:The FEBS journal (Online)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume
The FEBS journal
(2021). doi:10.1111/febs.16248
info:cnr-pdr/source/autori:Spizzichino, Sharon; Boi, Dalila; Boumis, Giovanna; Lucchi, Roberta; Liberati, Francesca Romana; Capelli, Davide; Montanari, Roberta; Pochetti, Giorgio; Piacentini, Roberta; Parisi, Giacomo; Paone, Alessio; Rinaldo, Serena; Contestabile, Roberto; Tramonti, Angela; Paiardini, Alessandro; Giardina, Giorgio; Cutruzzolà, Francesca/titolo:Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex/doi:10.1111%2Ffebs.16248/rivista:The FEBS journal (Print)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume
De novo thymidylate synthesis is a crucial pathway for normal and cancer cells. Deoxythymidine monophosphate (dTMP) is synthesized by the combined action of three enzymes: serine hydroxymethyltransferase (SHMT1), dihydrofolate reductase (DHFR) and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d9651953ac1a1098accf515108c1dd
http://hdl.handle.net/11573/1584599
http://hdl.handle.net/11573/1584599
Autor:
Giancarlo Solaini, Chiara Lanzillotta, Maria Chiara Magnifico, Amani Bouzidi, Francesca Cutruzzolà, Giovanna Boumis, Serena Rinaldo, Alessandra Baracca, Antonella Tramutola, Giorgio Giardina, Clotilde Lauro, Marzia Perluigi, Francesca Romana Liberati, Alessio Paone, Gianluca Sgarbi, Alessandro Paiardini, Cristina Limatola, Alberto Macone
Publikováno v:
Cell Death and Disease, Vol 11, Iss 11, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Nutrient utilization and reshaping of metabolism in cancer cells is a well-known driver of malignant transformation. Less clear is the influence of the local microenvironment on metastasis formation and choice of the final organ to invade. Here we sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b869792681305b796e2974fe5fbda2
http://hdl.handle.net/11573/1463758
http://hdl.handle.net/11573/1463758
Autor:
Sharon Spizzichino, Serena Rinaldo, Francesca Romana Liberati, Francesca Cutruzzolà, Amani Bouzidi, Giovanna Boumis, Alessio Paone, Alberto Macone, Giorgio Giardina
Publikováno v:
Cancers, Vol 13, Iss 2891, p 2891 (2021)
Cancers
Cancers
Simple Summary Why some cancers choose to form metastases in one organ rather than another is still largely unknown. In this review, we summarized the available information on the possible mechanisms controlling this choice. In particular, we tried t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10fc764636f4507fb61211382cd13722
https://www.mdpi.com/2072-6694/13/12/2891
https://www.mdpi.com/2072-6694/13/12/2891