Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Francesca R. Buccellato"'
Autor:
Francesca R. Buccellato, Marianna D’Anca, Gianluca Martino Tartaglia, Massimo Del Fabbro, Elio Scarpini, Daniela Galimberti
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13900 (2023)
In an ever-increasing aged world, Alzheimer’s disease (AD) represents the first cause of dementia and one of the first chronic diseases in elderly people. With 55 million people affected, the WHO considers AD to be a disease with public priority. U
Externí odkaz:
https://doaj.org/article/92991ca05ab84e4394445bd0b69dcdb3
Autor:
Marianna D’Anca, Francesca R. Buccellato, Gianluca Martino Tartaglia, Massimo Del Fabbro, Paola Muti, Elio Scarpini, Daniela Galimberti, Laura Ghezzi
Publikováno v:
Applied Sciences, Vol 13, Iss 10, p 5881 (2023)
Multiple sclerosis (MS) is the most prevalent demyelinating disease of the central nervous system (CNS) with an autoimmune component affecting young adults in their third decade of life. The etiology is still undefined, but myelin damage is mainly du
Externí odkaz:
https://doaj.org/article/f007fef5bf094b4cb192b2b3f8e23899
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2261 (2022)
Alzheimer’s disease (AD) is the most common cause of neurodegenerative dementia, whilst Parkinson’s disease (PD) is a neurodegenerative movement disorder. These two neurodegenerative disorders share the accumulation of toxic proteins as a patholo
Externí odkaz:
https://doaj.org/article/f42ea360f3dc4c1fbfca0d8224948bda
Autor:
Maria Serpente, Laura Ghezzi, Chiara Fenoglio, Francesca R. Buccellato, Giorgio G. Fumagalli, Emanuela Rotondo, Marina Arcaro, Andrea Arighi, Daniela Galimberti
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8487 (2022)
Primary progressive aphasia (PPA) damages the parts of the brain that control speech and language. There are three clinical PPA variants: nonfluent/agrammatic (nfvPPA), logopenic (lvPPA) and semantic (svPPA). The pathophysiology underlying PPA varian
Externí odkaz:
https://doaj.org/article/dafe3a8cf3af42ef9e4270529ad35fc1
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4134 (2022)
In the fascinating landscape of non-coding RNAs (ncRNAs), circular RNAs (circRNAs) are peeping out as a new promising and appreciated class of molecules with great potential as diagnostic and prognostic biomarkers. They come from circularization of s
Externí odkaz:
https://doaj.org/article/83b260a8171b41ba8d183f9fc7e3bc4d
Publikováno v:
Antioxidants
Antioxidants, Vol 10, Iss 1353, p 1353 (2021)
Antioxidants, Vol 10, Iss 1353, p 1353 (2021)
Alzheimer’s disease (AD) is a neurodegenerative disorder accounting for over 50% of all dementia patients and representing a leading cause of death worldwide for the global ageing population. The lack of effective treatments for overt AD urges the
Autor:
Francesca R. Buccellato, Chiara Fenoglio, Caterina Visconte, Elio Scarpini, Daniela Galimberti, Marianna D'Anca
Publikováno v:
Cells
Cells, Vol 10, Iss 1733, p 1733 (2021)
Cells, Vol 10, Iss 1733, p 1733 (2021)
Although extracellular vesicles (EVs) were initially relegated to a waste disposal role, nowadays, they have gained multiple fundamental functions working as messengers in intercellular communication as well as exerting active roles in physiological
Publikováno v:
Glia. 45:406-411
In the present study, we hypothesized that cobalamin (Cbl) deficiency might affect astrocytes and oligodendrocytes of rat spinal cord (SC) differently. Radiolabeled Cbl ([Cyano-14C]cyano-Cbl) was used to investigate whether the in vitro uptake of Cbl
Autor:
Luigi Sironi, Daniela Veber, Francesca R. Buccellato, Elisabetta Gianazza, Ivano Eberini, Giuseppe Scalabrino, Elena Mutti
Publikováno v:
Biochemical Journal. 374:239-246
We studied the changes in the proteome of CSF (cerebrospinal fluid) in two animal models of Cbl (cobalamin) deficiency: TGX (totally gastrectomized) rats and rats fed a Cbl-D (Cbl-deficient) diet. Two-dimensional PAGE was used to detect qualitative a
Autor:
Francesca R. Buccellato, Alberto Morabito, Daniela Veber, Giuseppe Scalabrino, Valerio Magnaghi, Roberto Cosimo Melcangi
Publikováno v:
The FASEB Journal. 16:1-13
We have demonstrated previously that chronic vitamin B12 [cobalamin (Cbl)] deficiency preferentially affects glial cells in the rat central nervous system (CNS) and severely affects peripheral glial cells independently of and concomitantly with the c