Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Francesca Puca"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8108 (2022)
Diet and lifestyle factors greatly affect health and susceptibility to diseases, including cancer. Stem cells’ functions, including their ability to divide asymmetrically, set the rules for tissue homeostasis, contribute to health maintenance, and
Externí odkaz:
https://doaj.org/article/235c699c71a342029315ea6ba54c1235
Autor:
Giulio F. Draetta, Andrea Viale, Costas A. Lyssiotis, Pier Paolo Scaglioni, Giannicola Genovese, Angela K. Deem, Sisi Gao, Li Zhang, Maureen Kachman, Zachary P. Tolstyka, Mengrou Shan, Lin Tan, Philip L. Lorenzi, Erik P. Sulman, Frederick F. Lang, Sanjana Srinivasan, Sahil Seth, Pushan Dasgupta, Joy Gumin, Edoardo Del Poggetto, Federica Carbone, Ciro Zanca, Jintan Liu, Emmet Huang-Hobbs, Alessandro Carugo, Piergiorgio Pettazzoni, Caterina Bartolacci, Fei Yu, Francesca Puca
Glioblastoma (GBM) is highly resistant to chemotherapies, immune-based therapies, and targeted inhibitors. To identify novel drug targets, we screened orthotopically implanted, patient-derived glioblastoma sphere-forming cells using an RNAi library t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9012680724c9c88367f5f9bb3ac0bf34
https://doi.org/10.1158/2159-8290.c.6549482.v1
https://doi.org/10.1158/2159-8290.c.6549482.v1
Autor:
Giulio F. Draetta, Andrea Viale, Costas A. Lyssiotis, Pier Paolo Scaglioni, Giannicola Genovese, Angela K. Deem, Sisi Gao, Li Zhang, Maureen Kachman, Zachary P. Tolstyka, Mengrou Shan, Lin Tan, Philip L. Lorenzi, Erik P. Sulman, Frederick F. Lang, Sanjana Srinivasan, Sahil Seth, Pushan Dasgupta, Joy Gumin, Edoardo Del Poggetto, Federica Carbone, Ciro Zanca, Jintan Liu, Emmet Huang-Hobbs, Alessandro Carugo, Piergiorgio Pettazzoni, Caterina Bartolacci, Fei Yu, Francesca Puca
Supplementary Figures S1 through S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::426c9b71c727512490f2493fee2b2d53
https://doi.org/10.1158/2159-8290.22540823
https://doi.org/10.1158/2159-8290.22540823
Autor:
Fei Yu, Paul Leonard, Matthew Hamilton, Francesca Puca, Nhung Pham, Norma Rogers, Fernando Alvarez, C Rodriguez, Vinay Nair, Narahari Akkaladevi, Roopa Thapar, Scott Vaccaro, Andrea Mendiola, Quanyun Xu, Mary Geck Do, Jason Cross, Mick Soth, Yongying Jiang, Giulio Draetta, Philip Jones
Publikováno v:
Leading Edge of Cancer Research Symposium: Poster Session.
Autor:
Yalçın Kuzay, Alfredo Fusco, Teresa Savarese, Anna Pepe, Antonella Federico, Nadia Tosti, Francesca Puca, Marianna Colamaio, Sabrina Battista, Daniela Sarnataro, Federica D'Alessio, Sonia Morlando, Marco De Martino, Sihana Ziberi
Publikováno v:
Cell Cycle
Cell cycle (Georget. Tex.) 18 (2019): 1446–1457. doi:10.1080/15384101.2019.1618541
info:cnr-pdr/source/autori:Puca F.; Tosti N.; Federico A.; Kuzay Y.; Pepe A.; Morlando S.; Savarese T.; D'Alessio F.; Colamaio M.; Sarnataro D.; Ziberi S.; De Martino M.; Fusco A.; Battista S./titolo:HMGA1 negatively regulates NUMB expression at transcriptional and post transcriptional level in glioblastoma stem cells/doi:10.1080%2F15384101.2019.1618541/rivista:Cell cycle (Georget. Tex.)/anno:2019/pagina_da:1446/pagina_a:1457/intervallo_pagine:1446–1457/volume:18
Cell cycle (Georget. Tex.) 18 (2019): 1446–1457. doi:10.1080/15384101.2019.1618541
info:cnr-pdr/source/autori:Puca F.; Tosti N.; Federico A.; Kuzay Y.; Pepe A.; Morlando S.; Savarese T.; D'Alessio F.; Colamaio M.; Sarnataro D.; Ziberi S.; De Martino M.; Fusco A.; Battista S./titolo:HMGA1 negatively regulates NUMB expression at transcriptional and post transcriptional level in glioblastoma stem cells/doi:10.1080%2F15384101.2019.1618541/rivista:Cell cycle (Georget. Tex.)/anno:2019/pagina_da:1446/pagina_a:1457/intervallo_pagine:1446–1457/volume:18
Glioblastoma (GBM) is a lethal, fast-growing brain cancer, affecting 2-3 per 100,000 adults per year. It arises from multipotent neural stem cells which have reduced their ability to divide asymmetrically and hence divide symmetrically, generating in
Autor:
Frederick F. Lang, Joy Gumin, Francesca Puca, Maureen Kachman, Sahil Seth, Sisi Gao, Alessandro Carugo, Ciro Zanca, Philip L. Lorenzi, Sanjana Srinivasan, Piergiorgio Pettazzoni, Lin Tan, Edoardo Del Poggetto, Andrea Viale, Pushan Dasgupta, Giannicola Genovese, Pier Paolo Scaglioni, Erik P. Sulman, Zachary P. Tolstyka, Fei Yu, Costas A. Lyssiotis, Angela K. Deem, Emmet Huang-Hobbs, Caterina Bartolacci, Federica Carbone, Jintan Liu, Giulio Draetta, Mengrou Shan, Li Zhang
Publikováno v:
Cancer Discov
Glioblastoma (GBM) is highly resistant to chemotherapies, immune-based therapies, and targeted inhibitors. To identify novel drug targets, we screened orthotopically implanted, patient-derived glioblastoma sphere-forming cells using an RNAi library t
Autor:
Federica Carbone, Costas A. Lyssiotis, Li Zhang, Alessandro Carugo, Philip L. Lorenzi, Pushan Dasgupta, Ciro Zanca, Mengrou Shan, Zachary P. Tolstyka, Francesca Puca, Emmet Huang-Hobbs, Maureen Kachman, Andrea Viale, Jintan Liu, Erik P. Sulman, Fei Yu, Sahil Seth, Giulio Draetta, Lin Tan, Edoardo Del Poggetto, Joy Gumin, Angela K. Deem, Giannicola Genovese, Pier Paolo Scaglioni, Caterina Bertolacci, Frederick F. Lang, Piergiorgio Pettazzoni
SUMMARYGlioblastoma (GBM) is among the deadliest of human cancers. Despite extensive efforts, it has proven to be highly resistant to chemo- and immune-based therapeutic strategies, and little headway has been made with targeted inhibitors. Like many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::953009ae65156c8852890aad5ae2d134
https://doi.org/10.1101/2020.09.28.316554
https://doi.org/10.1101/2020.09.28.316554
Autor:
Alan Saghatelian, Matthew J. Kolar, Gabriele Sulli, Amy Rommel, Satchidananda Panda, Maksim V. Plikus, Inder M. Verma, Xiaojie Wang, Francesca Puca
Publikováno v:
Nature
Nature, vol 553, iss 7688
Nature, vol 553, iss 7688
The circadian clock imposes daily rhythms in cell proliferation, metabolism, inflammation and DNA damage response1, 2. Perturbations of these processes are hallmarks of cancer3 and chronic circadian rhythm disruption predisposes to tumor development1
Autor:
Giulio Draetta, Alessandro Sgambato, Prasenjit Dey, Federica Carbone, Melinda Soeung, Sara Loponte, Jose A. Karam, Rosalba Minelli, Nizar M. Tannir, Timothy P. Heffernan, Luigi Sapio, Dolores Lopez-Terrada, Alexander J. Lazar, Ziheng Chen, Alessandro Carugo, Andrea Viale, James Tepper, Priya Rao, Gabriel G. Malouf, Sara Lovisa, Xiaoping Su, Liren Li, Maria Svelto, Edoardo Del Poggetto, Cheryl Walker, Anirban Maitra, Frederick S. Robinson, Dinesh Rakheja, Charles W. M. Roberts, Sanjana Srinivasan, Giannicola Genovese, Samirkumar B. Amin, Francesca Puca, Durga Nand Tripathi, Pavlos Msaouel, George J. Netto
Publikováno v:
Cancer Cell
Alterations in chromatin remodeling genes have been increasingly implicated in human oncogenesis. Specifically, the biallelic inactivation of the SWI/SNF subunit SMARCB1 results in the emergence of extremely aggressive pediatric malignancies. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f8d4a4d5c781f00dbb31b5a270c831
http://hdl.handle.net/11591/421098
http://hdl.handle.net/11591/421098
Autor:
Inder M. Verma, Matthew J. Kolar, Maksim V. Plikus, Gabriele Sulli, Alan Saghatelian, Xiaojie Wang, Francesca Puca, Amy Rommel, Satchidananda Panda
Publikováno v:
Cancer Research. 78:5464-5464
The circadian clock drives daily rhythms in cell proliferation, metabolism, inflammation and DNA damage response. Perturbations of these processes are hallmarks of cancer, and circadian rhythm disruption predisposes to tumor development in animal mod