Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Francesca Pezzuto"'
Autor:
Maria Lina Tornesello, Raffaella Faraonio, Luigi Buonaguro, Clorinda Annunziata, Noemy Starita, Andrea Cerasuolo, Francesca Pezzuto, Anna Lucia Tornesello, Franco Maria Buonaguro
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Prolonged infection of uterine cervix epithelium with human papillomavirus (HPV) and constitutive expression of viral oncogenes have been recognized as the main cause of the complex molecular changes leading to transformation of cervical epithelial c
Externí odkaz:
https://doaj.org/article/0a055679ce4d427aa99e48a374fcc4e6
Frequency and geographic distribution of TERT promoter mutations in primary hepatocellular carcinoma
Publikováno v:
Infectious Agents and Cancer, Vol 12, Iss 1, Pp 1-9 (2017)
Abstract Primary hepatocellular carcinoma (HCC) mainly develops in subjects chronically infected with hepatitis B (HBV) and C (HCV) viruses through a multistep process characterized by the accumulation of genetic alterations in the human genome. Nucl
Externí odkaz:
https://doaj.org/article/4097d832900641958f285dd944d743f7
Autor:
Valli De Re, Maria Lina Tornesello, Mariangela De Zorzi, Laura Caggiari, Francesca Pezzuto, Patrizia Leone, Vito Racanelli, Gianfranco Lauletta, Laura Gragnani, Angela Buonadonna, Emanuela Vaccher, Anna Linda Zignego, Agostino Steffan, Franco M. Buonaguro
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Background and Aims: Polymorphisms in the immune response genes can contribute to clearance of hepatitis C virus (HCV) infection but also mediate liver inflammation and cancer pathogenesis. This study aimed to investigate the association of polymorph
Externí odkaz:
https://doaj.org/article/1f67a7943b7d4a74afdb56d00a93a35e
Autor:
Patrizia Leone, Agostino Steffan, Vito Racanelli, Mariangela De Zorzi, Maria Lina Tornesello, Francesca Rossi, Laura Caggiari, Riccardo Dolcetti, Anna Linda Zignego, Laura Gragnani, Gianfranco Lauletta, Franco M. Buonaguro, Francesca Pezzuto, Stefania Zanussi, Valli De Re, Ombretta Repetto
Publikováno v:
Liver International. 41:133-149
BACKGROUND: Genetic variants of IFNL4 and PDCD1 genes have been shown to influence the spontaneous clearance of hepatitis C virus (HCV) infection. We investigated the IFNL4 rs12979860 and the PDCD1 polymorphisms in 734 HCV-positive patients, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52af5c89e3c2001e1c47353bd2ce1144
https://doi.org/10.1111/liv.14667
https://doi.org/10.1111/liv.14667
Autor:
Federica Casiraghi, Camillo Carrara, Manuel Alfredo Podestà, Francesca Pezzuto, Marina Noris, Nadia Azzollini, Ariela Benigni, Marta Todeschini, Samantha Solini, Giuseppe Remuzzi, Sistiana Aiello, Pamela Y Rodriguez-Ordonez
Publikováno v:
Journal of the American Society of Nephrology. 31:517-531
Background In donor kidneys subjected to ischemia-reperfusion injury during kidney transplant, phagocytes coexpressing the F4/80 and CD11c molecules mediate proinflammatory responses and trigger adaptive immunity in transplantation through antigen pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::512847431768601f71ecf3d8c7df4166
https://doi.org/10.1681/asn.2019080778
https://doi.org/10.1681/asn.2019080778
Autor:
Luigi Buonaguro, Anna Lucia Tornesello, Franco M. Buonaguro, Tobias Knaute, Maria Lina Tornesello, Angelo Salomone Megna, Francesca Pezzuto, Francesco Izzo, Pavlo Holenya, Ulf Reimer
Background: Chronic infection with hepatitis C virus (HCV) is among the major causes of hepatic fibrosis, cirrhosis, as well as hepatocellular carcinoma (HCC), and it is associated with a significant risk of developing lymphoproliferative disorders.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8227b6f40cd8796ac0b13f860aea1ab
Autor:
Francesca Pezzuto, Franco M. Buonaguro, Elio Biffali, Francesco Izzo, Fabiana Tatangelo, Luigi Buonaguro, Pasquale De Luca, Maria Lina Tornesello
Publikováno v:
Cancers, Vol 13, Iss 3771, p 3771 (2021)
Cancers
Volume 13
Issue 15
Cancers
Volume 13
Issue 15
Telomerase reactivation during hepatocarcinogenesis is recurrently caused by two point mutations occurring most frequently at the nucleotide −124 (95%) and occasionally at the nucleotide −146 (<
5%) upstream of the TERT translational start
5%) upstream of the TERT translational start
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9870c2d2864d584500a36b03cde78513
https://www.mdpi.com/2072-6694/13/15/3771
https://www.mdpi.com/2072-6694/13/15/3771
Autor:
Vittoria Rago, Rocco Malivindi, Giuseppe E. De Benedetto, Isabella Pisano, Giuseppe Fiermonte, Francesco M. Lasorsa, Carmela Piazzolla, Christopher L. Riley, Angelo Vozza, Stephan J. Reshkin, Wolfgang Sommergruber, Gennaro Agrimi, Francesca Pezzuto, Rosa Angela Cardone, Simona N. Barile, Yuan Li, Pasquale Scarcia, Carlo M.T. Marobbio, Maria C. Vegliante, Ruggiero Gorgoglione, Edward M. Mills, Luigi Palmieri, Loredana Capobianco, Deborah Fratantonio, Susanna Raho, Maria Raffaella Greco, Francesco De Leonardis, Vincenza Dolce
The oncogenic KRAS mutation has a critical role in the initiation of human pancreatic ductal adenocarcinoma (PDAC) since it rewires glutamine metabolism to increase reduced nicotinamide adenine dinucleotide phosphate (NADPH) production, balancing cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::350f42fd8c68d5a5a3935b025a621e83
https://hdl.handle.net/11587/447928
https://hdl.handle.net/11587/447928
Autor:
Stefano Greggi, Francesca Pezzuto, Franco M. Buonaguro, Maria Lina Tornesello, Simona Losito, Gerardo Botti, Clorinda Annunziata, Franco Ionna, Luigi Buonaguro
Publikováno v:
International Journal of Cancer. 143:1153-1161
Two recurrent mutations (-124 G > A and -146 G > A) in the core promoter region of the human telomerase reverse transcriptase (TERT) gene create consensus binding sites for ETS transcription factors and cause increased TERT expression in several tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dfa3f7eca81e10ef3ffc4a216d52422
https://doi.org/10.1002/ijc.31412
https://doi.org/10.1002/ijc.31412
Autor:
Marilena Mister, Lorena Longaretti, Marta Todeschini, Linda Cassis, Susanna Tomasoni, Giuseppe Remuzzi, Nadia Azzollini, Sistiana Aiello, Ariela Benigni, Federica Rocchetta, Sara Conti, Silvia Faravelli, Marina Noris, Francesca Pezzuto, Matteo Breno, Caterina Mele
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-19 (2017)
Scientific Reports
Scientific Reports
We have previously shown that rat allogeneic DC, made immature by adenoviral gene transfer of the dominant negative form of IKK2, gave rise in-vitro to a unique population of CD4+CD25− regulatory T cells (dnIKK2-Treg). These cells inhibited Tcell r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a0946973a21f497a161d5b847d6a6a
http://link.springer.com/article/10.1038/s41598-017-08617-3
http://link.springer.com/article/10.1038/s41598-017-08617-3