Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Francesca Pellicano"'
Autor:
Marzia Vezzalini, Andrea Mafficini, Luisa Tomasello, Erika Lorenzetto, Elisabetta Moratti, Zeno Fiorini, Tessa L. Holyoake, Francesca Pellicano, Mauro Krampera, Cristina Tecchio, Mohamed Yassin, Nader Al-Dewik, Mohamed A. Ismail, Ali Al Sayab, Maria Monne, Claudio Sorio
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-11 (2017)
Abstract Background Protein tyrosine phosphatase receptor gamma (PTPRG) is a ubiquitously expressed member of the protein tyrosine phosphatase family known to act as a tumor suppressor gene in many different neoplasms with mechanisms of inactivation
Externí odkaz:
https://doaj.org/article/8e1412223b5b4e8fa36d87cc9b36e25b
Autor:
David Vetrie, Tessa L. Holyoake, Amy Sinclair, Andrew Crossan, Ashley Hamilton, Jennifer E. Cassels, Heather G. Jorgensen, Karen Dunn, Michelle Cruz, Paolo Gallipoli, Carla Guenther, Francesca Pellicano, Ross Kinstrie, Lisa E.M. Hopcroft, Peter Saffrey, Koorosh Korfi, Mary T. Scott
Supplementary Figure S1. mRNA levels of PRC2 components in CML and normal samples used in this study. Supplementary Figure S2. Effect of TKI treatment on mRNA levels of PRC2 components on CML cells in vitro. Supplementary Figure S3. Analysis of promo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06528855599a0e5901fa435f6c0c62d
https://doi.org/10.1158/2159-8290.22530986.v1
https://doi.org/10.1158/2159-8290.22530986.v1
Autor:
David Vetrie, Tessa L. Holyoake, Amy Sinclair, Andrew Crossan, Ashley Hamilton, Jennifer E. Cassels, Heather G. Jorgensen, Karen Dunn, Michelle Cruz, Paolo Gallipoli, Carla Guenther, Francesca Pellicano, Ross Kinstrie, Lisa E.M. Hopcroft, Peter Saffrey, Koorosh Korfi, Mary T. Scott
Supplementary Table S2. mRNA expression changes in CML and normal CD34+ cells resulting from treatment of EZHi (GSK343) (EMTAB-2893, MTAB-3552; Affymetrix HuGe 1.0 ST).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549cd39928ace0ab7e346fcac2612249
https://doi.org/10.1158/2159-8290.22530980
https://doi.org/10.1158/2159-8290.22530980
Autor:
Le Xuan Truong Nguyen, Akihiko Yoshimura, Haris Ali, Paul Koller, Danilo Perrotti, Yasmin Elhajmoussa, Junjing Qiao, Ivan Rodriguez, Lucy Ghoda, Fang Chen, Chen Liang, Anthony S. Stein, Bin Amber Zhang, Mhairi Copland, Shanshan Suo, Dandan Zhao, Guido Marcucci, Anjia Han, Francesca Pellicano, Dinh Hoa Hoang
Publikováno v:
Leukemia
Spred1 is highly expressed in normal hematopoietic stem cells (HSCs). Lack of Spred1 function has been associated with aberrant hematopoiesis and acute leukemias. In chronic myelogenous leukemia (CML), Spred1 is reduced in patients with accelerated p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46980ee78b573c89738b4d33e42d4e3
https://europepmc.org/articles/PMC9134843/
https://europepmc.org/articles/PMC9134843/
Autor:
Mansi Shah, Cassie J. Clarke, Anthony D. Whetton, G. Vignir Helgason, Mark Aspinall-O'Dea, Lorna Jackson, Ravi Bhatia, Gustavo Leone, Tessa L. Holyoake, Sheela A. Abraham, Lisa E. M. Hopcroft, Kamil R. Kranc, Laura Park, Alan Hair, Amy Sinclair, Francesca Pellicano, Mary T. Scott
Publikováno v:
Pellicano, F, Park, L, Hopcroft, L E M, Shah, M, Jackson, L, Scott, M T, Clarke, C J, Sinclair, A, Abraham, S A, Hair, A, Helgason, G V, Aspinall-O’Dea, M, Bhatia, R, Leone, G, Kranc, K, Whetton, A D & Holyoake, T L 2018, ' Hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival ', Blood . https://doi.org/10.1182/blood-2017-05-783845
Chronic myeloid leukemia (CML) stem/progenitor cells (SPCs) express a transcriptional program characteristic of proliferation, yet can achieve and maintain quiescence. Understanding the mechanisms by which leukemic SPCs maintain quiescence will help
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63629abef8d2feff7e8c56343f69e0f4
https://doi.org/10.1182/blood-2017-05-783845
https://doi.org/10.1182/blood-2017-05-783845
Autor:
Bin Zhang, Mhairi Copland, Herman Wu, Stephen J. Forman, Dandan Zhao, Ravi Bhatia, Huafeng Wang, Guido Marcucci, Le Xuan Truong Nguyen, Adrienne M. Dorrance, David S. Snyder, Piotr Swiderski, Tessa L. Holyoake, Ching-Cheng Chen, Vinod Pullarkat, Allen Lin, Bijender Kumar, Lisa E. M. Hopcroft, Tinisha McDonald, Haris Ali, Anthony S. Stein, Francesca Pellicano, Estelle Troadec, Danilo Perrotti, Nadia Carlesso, Casey J Brewer, Ya-Huei Kuo, Ling Li, Marcin Kortylewski, Calvin J. Kuo, Yu-Lin Su, Yate Ching Yuan
Publikováno v:
Nature medicine
Leukemia stem cells (LSCs) in individuals with chronic myelogenous leukemia (CML) (hereafter referred to as CML LSCs) are responsible for initiating and maintaining clonal hematopoiesis. These cells persist in the bone marrow (BM) despite effective i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee70a03cf561424a09cec6450759e4d
https://doi.org/10.1038/nm.4499
https://doi.org/10.1038/nm.4499
Autor:
Lijing Fang, Heather G. Jørgensen, Tessa L. Holyoake, Wu Su, Eduardo Gómez-Castañeda, Francesca Pellicano, Lorna Jackson, Glenn A. Burley, Ya-Ching Hsieh, Kourosh Hayatigolkhatmi, Giacomo Padroni
Publikováno v:
Blood Cells, Molecules, and Diseases. 69:119-122
No abstract available.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaedbd590a3f7dbe57d3319bfd48bb62
https://doi.org/10.1016/j.bcmd.2017.11.002
https://doi.org/10.1016/j.bcmd.2017.11.002
Autor:
Cristina Tecchio, Claudio Sorio, Tessa L. Holyoake, Luisa Tomasello, Nader Al-Dewik, Ali Al Sayab, Zeno Fiorini, Elisabetta Moratti, Erika Lorenzetto, Mauro Krampera, Francesca Pellicano, Mohamed A. Yassin, Andrea Mafficini, Marzia Vezzalini, Mohamed A. Ismail, Maria Monne
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-11 (2017)
Journal of Hematology & Oncology
Journal of Hematology & Oncology
Background Protein tyrosine phosphatase receptor gamma (PTPRG) is a ubiquitously expressed member of the protein tyrosine phosphatase family known to act as a tumor suppressor gene in many different neoplasms with mechanisms of inactivation including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9139b6b4e8f9cf66914001be0470c4
http://link.springer.com/article/10.1186/s13045-017-0494-z
http://link.springer.com/article/10.1186/s13045-017-0494-z
Autor:
Glenn A. Burley, Giacomo Padroni, Lorna Jackson, Lijing Fang, Wu Su, Eduardo Gómez-Castañeda, K. Hayatigolkhatmi, Ya-Ching Hsieh, Francesca Pellicano, Heather G. Jørgensen
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(18)
Tyrosine kinase inhibitor (TKI) therapy is the standard treatment for chronic phase (CP)-chronic myeloid leukemia (CML), yet patients in blast crisis (BC) phase of CML are unlikely to respond to TKI therapy. The transcription factor E2F1 is a down-st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77d4ff4c3d878717692b8b7e48ff521
https://pubmed.ncbi.nlm.nih.gov/31378570
https://pubmed.ncbi.nlm.nih.gov/31378570
Autor:
Andrew Pierce, Michael J. Walker, Anthony D. Whetton, Andrew J.K. Williamson, Mark Aspinall-O'Dea, Francesca Pellicano, Mary T. Scott, Tessa L. Holyoake
Publikováno v:
Nature Protocols. 10:149-168
This protocol describes a highly reproducible antibody-based method that provides protein level and phosphorylation status information from nanogram quantities of protein cell lysate. Nanocapillary isoelectric focusing (cIEF) combines with UV-activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bad29d056056d0f54e8ab85195f0bc3
https://doi.org/10.1038/nprot.2015.007
https://doi.org/10.1038/nprot.2015.007