Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Francesca Nani"'
Autor:
Chiayu Q. Chiu, Frédéric Knoflach, Francesca Nani, Monika P. Jadi, Maria-Clemencia Hernandez, Michael J. Higley, Thomas M. Morse
SummaryBrain activity is highly regulated by GABAergic activity, which acts via GABAARs to suppress somatic spike generation as well as dendritic synaptic integration and calcium signaling. Tonic GABAergic conductances mediated by distinct receptor s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ce7e737e9238358224faa5b79b839c
https://doi.org/10.1101/2020.04.22.055137
https://doi.org/10.1101/2020.04.22.055137
Autor:
Verena Tretter, Trevor G. Smart, Raquel Revilla-Sanchez, Stephen J. Moss, Damian P. Bright, Francesca Nani
GABA-mediated tonic and phasic inhibition of thalamic relay neurons of the dorsal lateral geniculate nucleus (dLGN) was studied after ablating tyrosine (Y) phosphorylation of receptor γ2-subunits. As phosphorylation of γ2 Y365 and Y367 reduces rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b4bd1a47609b27f52fd1651a7fc6dc
https://europepmc.org/articles/PMC4400286/
https://europepmc.org/articles/PMC4400286/
In vitro preparations of the neonatal rat spinal cord or brainstem are useful to investigate the organization of motor networks and their dysfunction in neurological disease models. Long-term spinal cord organotypic cultures can extend our understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9b387a17d9fcc0b9ebe2a3029de3f7
http://hdl.handle.net/20.500.11767/16165
http://hdl.handle.net/20.500.11767/16165
Hypoglossal motoneurons (HMs) are respiration-related brainstem neurons that command rhythmic contraction of the tongue muscles in concert with the respiratory drive. In experimental conditions, HMs can exhibit a range of rhythmic patterns that may s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af80c62736434361e60c8647120f00cf
http://hdl.handle.net/20.500.11767/12045
http://hdl.handle.net/20.500.11767/12045
Oxidative stress of motoneurons is believed to be an important contributor to neurodegeneration underlying the familial (and perhaps even the sporadic) form of amyotrophic lateral sclerosis (ALS). This concept has generated numerous rodent genetic mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5008fc54f1d84889aa77770b3be463
http://hdl.handle.net/20.500.11767/12504
http://hdl.handle.net/20.500.11767/12504
Publikováno v:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 364(1529)
The brainstem nucleus hypoglossus contains motoneurons that provide the exclusive motor nerve supply to the tongue. In addition to voluntary tongue movements, tongue muscles rhythmically contract during a wide range of physiological activities, such