Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Francesca Metruccio"'
Autor:
European Food Safety Authority (EFSA), Federica Crivellente, Antonio F. Hernández‐Jerez, Anna Lanzoni, Francesca Metruccio, Luc Mohimont, Dimitra Nikolopoulou, Anna F. Castoldi
Publikováno v:
EFSA Journal, Vol 22, Iss 3, Pp n/a-n/a (2024)
Abstract EFSA updated its previous work on the establishment of specific effects that are considered relevant for grouping pesticide residues targeting the thyroid and for performing the retrospective assessment of dietary cumulative risk (CRA). The
Externí odkaz:
https://doaj.org/article/4e14daa56d30446095859d45c0585aef
Autor:
European Food Safety Authority (EFSA), Chris Anagnostopoulos, Maria Anastassiadou, Anna Federica Castoldi, Adeline Cavelier, Tamara Coja, Federica Crivellente, Bruno Dujardin, Andy Hart, Wim Hooghe, Samira Jarrah, Kyriaki Machera, Elena Menegola, Francesca Metruccio, Christian Sieke, Luc Mohimont
Publikováno v:
EFSA Journal, Vol 20, Iss 10, Pp n/a-n/a (2022)
Abstract EFSA established cumulative assessment groups and conducted retrospective cumulative risk assessments for two types of craniofacial alterations (alterations due to abnormal skeletal development, head soft tissue alterations and brain neural
Externí odkaz:
https://doaj.org/article/499598268be341f4a2d87544cd85e417
Publikováno v:
Toxicology Reports, Vol 7, Iss , Pp 510-519 (2020)
Vitamin A plays a vital role during embryo development as most precursor of embryonic retinoic acid, a key morphogen during embryogenesis. Carotenoids, including β-carotene, are important vegetal source of Vitamin A and in contrast to teratogenic po
Externí odkaz:
https://doaj.org/article/35fcbf035f1d4981a935ffb2f5b7d4dc
Publikováno v:
Archives of toxicology.
Abstract The prenatal exposure to ethanol (Eth), fluconazole (FLUCO) and sodium valproate (VPA) is related to effects on development, producing characteristic syndromic pictures. Among embryotoxic effects described for the three molecules, the altera
Publikováno v:
Archives of toxicology. 96(10)
Craniofacial defects are one of the most frequent abnormalities at birth, but their experimental evaluation in animal models requires complex procedures. The aim of the present work is the comparison of different methodologies to identify dose- and s
Autor:
Maria Battistoni, Renato Bacchetta, Francesca Di Renzo, Francesca Metruccio, Angelo Moretto, Elena Menegola
In compliance to animal welfare 3Rs principle there is a great demand for refined tests alternative to classical mammal teratogenicity tests. We propose a refined alternative amphibian method (R-FETAX) to evaluate chemical induced embryotoxicity. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f51f46996937cc9bd2716552c9fc1786
http://hdl.handle.net/11577/3418251
http://hdl.handle.net/11577/3418251
Autor:
Chris, Anagnostopoulos, Maria, Anastassiadou, Anna Federica, Castoldi, Adeline, Cavelier, Tamara, Coja, Federica, Crivellente, Bruno, Dujardin, Andy, Hart, Wim, Hooghe, Samira, Jarrah, Kyriaki, Machera, Elena, Menegola, Francesca, Metruccio, Christian, Sieke, Luc, Mohimont
EFSA established cumulative assessment groups and conducted retrospective cumulative risk assessments for two types of craniofacial alterations (alterations due to abnormal skeletal development, head soft tissue alterations and brain neural tube defe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::23c098a58ebeeb365d46415a1c64ab81
https://hdl.handle.net/2434/940005
https://hdl.handle.net/2434/940005
Autor:
Anna Beronius, Francesca Metruccio, Anastasia Spyropoulou, Maria Battistoni, Johanna Zilliacus, Angelo Moretto, Kyriaki Machera, Christina H.J. Veltman, Katerina Kyriakopoulou, Francesca Di Renzo, Elena Menegola, Leo T.M. van der Ven, Mirjam Luijten
Adverse outcome pathway (AOP) is a conceptual framework that links a molecular initiating event (MIE) via intermediate key events (KEs) with adverse effects (adverse outcomes, AO) relevant for risk assessment, through defined KE relationships (KERs).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0322018121b0608f40205a9d87eb87
http://hdl.handle.net/11577/3394858
http://hdl.handle.net/11577/3394858
Autor:
Angelo Moretto, Francesca Metruccio
Publikováno v:
Current Opinion in Toxicology. :21-26
Substances that act via a genotoxic mechanism are considered to follow a low dose linear relationship with the absence of a threshold. The discussion on the existence of a threshold for genotoxic (mutagenic and clastogenic) compounds appears sometime