The Transcription Regulator Patz1 Is Essential for Neural Stem Cell Maintenance and Proliferation

Autor: Sara Mancinelli, Michela Vitiello, Maria Donnini, Francesca Mantile, Giuseppe Palma, Antonio Luciano, Claudio Arra, Laura Cerchia, Giovanna Lucia Liguori, Monica Fedele

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Proper regulation of neurogenesis, the process by which new neurons are generated from neural stem and progenitor cells (NS/PCs), is essential for embryonic brain development and adult brain function. The transcription regulator Patz1 is ubiquitously

Externí odkaz: https://doaj.org/article/1a9167aee69749cb8ef0c6bdca4a2380

Vaccination against β-Amyloid as a Strategy for the Prevention of Alzheimer’s Disease

Autor: Francesca Mantile, Antonella Prisco

Publikováno v: Biology, Vol 9, Iss 12, p 425 (2020)

Vaccination relies on the phenomenon of immunity, a long-term change in the immunological response to subsequent encounters with the same pathogen that occurs after the recovery from some infectious diseases. However, vaccination is a strategy that c

Externí odkaz: https://doaj.org/article/45e2b3b730d0406abb6d0762608cb470

Alum and squalene-oil-in-water emulsion enhance the titer and avidity of anti-Aβ antibodies induced by multimeric protein antigen (1-11)E2, preserving the Igg1-skewed isotype distribution.

Autor: Francesca Mantile, Maria Trovato, Andrea Santoni, Pasquale Barba, Simone Ottonello, Piergiuseppe De Berardinis, Antonella Prisco

Publikováno v: PLoS ONE, Vol 9, Iss 7, p e101474 (2014)

The development of active immunotherapy for Alzheimer's disease (AD) requires the identification of immunogens that can ensure a high titer antibody response toward Aβ, while minimizing the risks of adverse reactions. Multimeric protein (1-11)E2 ind

Externí odkaz: https://doaj.org/article/c9a1d111776c463cae1a06d30f599611

Biological role and clinical relevance of extracellular vesicles as key mediators of cell communication in cancer

Autor: Paola Franco, Giovanna L. Liguori, Francesca Mantile, Maria Patrizia Stoppelli

Publikováno v: Advances in Biomembranes and Lipid Self-Assembly volume 33
Advances in Biomembranes and Lipid Self-Assembly ISBN: 9780128246085
Biological Membrane Vesicles: Scientific, Biotechnological and Clinical Considerations, pp. 37–117. Paris: Elsevier, 2021
info:cnr-pdr/source/autori:Mantile F., Franco P., Stoppelli M.P., Liguori G.L./titolo:Biological role and clinical relevance of extracellular vesicles as key mediators of cell communication in cancer/titolo_volume:Biological Membrane Vesicles: Scientific, Biotechnological and Clinical Considerations/curatori_volume:/editore: /anno:2021

Cells of multicellular organisms constantly communicate with each other during development as well as in adult life to regulate body homeostasis and physiology. The sender cells may either signal to themselves or to specific recipient ones, thus infl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423b00a8cd13645cab48441a03dffd01

Analysis of the Consolidation Phase of Immunological Memory within the IgG Response to a B Cell Epitope Displayed on a Filamentous Bacteriophage

Autor: Piergiuseppe De Berardinis, Angelo Capasso, Francesca Mantile, Antonella Prisco

Publikováno v: Microorganisms 8 (2020). doi:10.3390/microorganisms8040564
info:cnr-pdr/source/autori:Mantile, Francesca; Capasso, Angelo; De Berardinis, Piergiuseppe; Prisco, Antonella/titolo:Analysis of the Consolidation Phase of Immunological Memory within the IgG Response to a B Cell Epitope Displayed on a Filamentous Bacteriophage/doi:10.3390%2Fmicroorganisms8040564/rivista:Microorganisms/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Microorganisms, Vol 8, Iss 564, p 564 (2020)
Microorganisms

Immunological memory can be defined as the ability to mount a response of greater magnitude and with faster kinetics upon re-encounter of the same antigen. We have previously reported that a booster dose of a protein antigen given 15 days after the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43dd1688c7a97b6e7e173e0393f840ff
http://www.cnr.it/prodotto/i/434540