Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Francesca M. Alves"'
Autor:
Francesca M. Alves, Kai Kysenius, Marissa K. Caldow, Justin P. Hardee, Jin D. Chung, Jennifer Trieu, Dominic J. Hare, Peter J. Crouch, Scott Ayton, Ashley I. Bush, Gordon S. Lynch, René Koopman
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 3, Pp 1541-1553 (2022)
Abstract Background Oxidative stress is implicated in the pathophysiology of Duchenne muscular dystrophy (DMD, caused by mutations in the dystrophin gene), which is the most common and severe of the muscular dystrophies. To our knowledge, the distrib
Externí odkaz:
https://doaj.org/article/da04fde3e0e44d6e87bd46e1112410fb
Autor:
Francesca M. Alves, Kai Kysenius, Marissa K. Caldow, Justin P. Hardee, Peter J. Crouch, Scott Ayton, Ashley I. Bush, Gordon S. Lynch, René Koopman
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 2, Pp 476-492 (2021)
Abstract Background Oxidative stress is implicated in the insidious loss of muscle mass and strength that occurs with age. However, few studies have investigated the role of iron, which is elevated during ageing, in age‐related muscle wasting and b
Externí odkaz:
https://doaj.org/article/e86c9cdf41484654933945359e602e47
Autor:
Daniel J. Ham, Anastasia Gardner, Tahnee L. Kennedy, Jennifer Trieu, Timur Naim, Annabel Chee, Francesca M. Alves, Marissa K. Caldow, Gordon S. Lynch, René Koopman
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract Duchenne muscular dystrophy (DMD) is an X-linked genetic disease characterized by progressive muscle wasting and weakness and premature death. Glucocorticoids (e.g. prednisolone) remain the only drugs with a favorable impact on DMD patients,
Externí odkaz:
https://doaj.org/article/6271200ce1974e419391ebe4bea3de4c
Autor:
Francesca M. Alves, Marissa K. Caldow, Jennifer Trieu, Tim Naim, Magdalene K. Montgomery, Matthew J. Watt, Gordon S. Lynch, René Koopman
Publikováno v:
Clinical Nutrition Experimental, Vol 24, Iss , Pp 83-91 (2019)
Summary: Background & aims: Dystrophic muscle fibres are fragile and prone to breakage, leading to impaired Ca2+ homeostasis and excessive inflammation, resulting in muscle wasting and weakness. Choline, an essential water-soluble nutrient, is involv
Externí odkaz:
https://doaj.org/article/72bfb56772184122be201bd75390b68a
Autor:
Gordon S. Lynch, Francesca M. Alves, Scott Ayton, Ashley I. Bush, Justin P. Hardee, Kai Kysenius, Marissa K. Caldow, René Koopman, Peter J. Crouch
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 2, Pp 476-492 (2021)
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle
Background Oxidative stress is implicated in the insidious loss of muscle mass and strength that occurs with age. However, few studies have investigated the role of iron, which is elevated during ageing, in age‐related muscle wasting and blunted re
Autor:
Francesca M. Alves, Marissa K. Caldow, Sheridan L. Helman, Scott Ayton, Ashley I. Bush, Gordon S. Lynch, David M. Frazer, René Koopman
Publikováno v:
Biochimica et biophysica acta. General subjects. 1866(3)
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences.
Sarcopenia is an age-related condition of slow, progressive loss of muscle mass and strength, which contributes to frailty, increased risk of hospitalization and mortality, and increased health care costs. The incidence of sarcopenia is predicted to
Autor:
Gordon S. Lynch, Magdalene K. Montgomery, Marissa K. Caldow, Matthew J. Watt, Tim Naim, Jennifer Trieu, René Koopman, Francesca M. Alves
Publikováno v:
Clinical Nutrition Experimental, Vol 24, Iss, Pp 83-91 (2019)
Summary: Background & aims: Dystrophic muscle fibres are fragile and prone to breakage, leading to impaired Ca2+ homeostasis and excessive inflammation, resulting in muscle wasting and weakness. Choline, an essential water-soluble nutrient, is involv
Autor:
Jennifer Trieu, Timur Naim, Francesca M. Alves, Tahnee L. Kennedy, Anastasia Gardner, Daniel J. Ham, René Koopman, Gordon S. Lynch, Annabel Chee, Marissa K. Caldow
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Duchenne muscular dystrophy (DMD) is an X-linked genetic disease characterized by progressive muscle wasting and weakness and premature death. Glucocorticoids (e.g. prednisolone) remain the only drugs with a favorable impact on DMD patients, but not