Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Francesca M Gardner"'
Autor:
Debaki R. Howlader, Rahul Shubhra Mandal, Ti Lu, Suhrid Maiti, Zackary K. Dietz, Sayan Das, Sean K. Whittier, Aaron C. Nagel, Satabdi Biswas, David J. Varisco, Francesca M. Gardner, Robert K. Ernst, William D. Picking, Wendy L. Picking
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Pseudomonas aeruginosa (Pa) is an opportunistic bacterial pathogen responsible for severe hospital acquired infections in immunocompromised and elderly individuals. Emergence of increasingly drug resistant strains and the absence of a broad-spectrum
Externí odkaz:
https://doaj.org/article/045977411a494c21b6ddb2526b664939
Autor:
Matthew Sorensen, Courtney E. Chandler, Francesca M. Gardner, Salma Ramadan, Prasanna D. Khot, Lisa M. Leung, Christine E. Farrance, David R. Goodlett, Robert K. Ernst, Erik Nilsson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Rapid infection diagnosis is critical to improving patient treatment and outcome. Recent studies have shown microbial lipids to be sensitive and selective biomarkers for identifying bacterial and fungal species and antimicrobial resistance.
Externí odkaz:
https://doaj.org/article/a15136a5d376457a8d05aa37957a3c9b
Autor:
Richard D. Smith, Christi L. McElheny, Jerilyn R. Izac, Francesca M. Gardner, Courtney E. Chandler, David R. Goodlett, Yohei Doi, J. Kristie Johnson, Robert K. Ernst
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT Enterobacter species are classified as high-priority pathogens due to high prevalence of multidrug resistance from persistent antibiotic use. For Enterobacter infections caused by multidrug-resistant isolates, colistin (polymyxin E), a last-
Externí odkaz:
https://doaj.org/article/2d187e73793844089023789bedcd291c
Autor:
Debaki R. Howlader, Sayan Das, Ti Lu, Gang Hu, David J. Varisco, Zackary K. Dietz, Sierra P. Walton, Siva Sai Kumar Ratnakaram, Francesca M. Gardner, Robert K. Ernst, William D. Picking, Wendy L. Picking
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Pseudomonas aeruginosa is an opportunistic pathogen responsible for a wide range of infections in humans. In addition to its innate antibiotic resistance, P. aeruginosa is very effective in acquiring resistance resulting in the emergence of multi-dru
Externí odkaz:
https://doaj.org/article/66c6b6c331804934846b2aa4b9efbfe7
Autor:
Matthew E. Sherman, Richard D. Smith, Francesca M. Gardner, David R. Goodlett, Robert K. Ernst
Publikováno v:
J Am Soc Mass Spectrom
Lipid A, the hydrophobic anchor of lipopolysaccharide (LPS) present in the outer membrane of Gram-negative bacteria, serves as a target for cationic antimicrobial peptides, such as polymyxins. Membrane stress from polymyxins results in activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05dbf3bfea74809f9ca0c9abbbac6ca
https://doi.org/10.1021/jasms.2c00266
https://doi.org/10.1021/jasms.2c00266
Autor:
Kelsey A. Gregg, Erin Harberts, Francesca M. Gardner, Mark R. Pelletier, Corinne Cayatte, Li Yu, Michael P. McCarthy, Jason D. Marshall, Robert K. Ernst
Publikováno v:
mBio, Vol 8, Iss 3 (2017)
ABSTRACT Adjuvant properties of bacterial cell wall components like MPLA (monophosphoryl lipid A) are well described and have gained FDA approval for use in vaccines such as Cervarix. MPLA is the product of chemically modified lipooligosaccharide (LO
Externí odkaz:
https://doaj.org/article/9e94f7b9ae6c480f9062857e69a6fc14
Autor:
Zackary K Dietz, Siva Sai Kumar Ratnakaram, Debaki R Howlader, Sierra P Walton, David J Varisco, Ti Lu, Gang Hu, Robert K. Ernst, Francesca M. Gardner, Wendy L. Picking, William D. Picking, Sayan Das
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Pseudomonas aeruginosa is an opportunistic pathogen responsible for a wide range of infections in humans. In addition to its innate antibiotic resistance, P. aeruginosa is very effective in acquiring resistance resulting in the emergence of multi-dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7df0cf2392cb320cc1759d5919b0743
https://www.frontiersin.org/articles/10.3389/fphar.2021.706157/full
https://www.frontiersin.org/articles/10.3389/fphar.2021.706157/full
Autor:
Randi D. Rotjan, Jonathan C. Kagan, Timothy M. Shank, Kevin S. Bonham, Robert K. Ernst, David R. Goodlett, Erik E. Cordes, Richard J.H. Smith, Valentina Poli, Francesca M. Gardner, Anna E. Gauthier, Ivan Zanoni, Aranteiti Tekiau, Courtney E. Chandler, Steven J. Biller
Publikováno v:
Sci Immunol
The assumption of near-universal bacterial detection by pattern recognition receptors is a foundation of immunology. The limits of this pattern recognition concept, however, remain undefined. As a test of this hypothesis, we determined whether mammal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4767ee26e7ea8d0fe41f9961aa2f6a31
https://doi.org/10.1126/sciimmunol.abe0531
https://doi.org/10.1126/sciimmunol.abe0531
Autor:
Erik Nilsson, Robert K. Ernst, David R. Goodlett, Francesca M. Gardner, Courtney E. Chandler, Prasanna D. Khot, Matthew Sorensen, Salma Ramadan, Lisa M. Leung, Christine E. Farrance
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Rapid infection diagnosis is critical to improving patient treatment and outcome. Recent studies have shown microbial lipids to be sensitive and selective biomarkers for identifying bacterial and fungal species and antimicrobial resistance. Practical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9430ca6af00bfa68cafc09d69e94a0fc
https://pubmed.ncbi.nlm.nih.gov/33299017
https://pubmed.ncbi.nlm.nih.gov/33299017
Autor:
Belita N. Opene, Yohei Doi, Robert K. Ernst, Roberta T. Mettus, Erin L. Fowler, Robert A. Myers, Courtney E. Chandler, Sarah L. Bowler, Christi L. McElheny, David R. Goodlett, Francesca M. Gardner, Lisa M. Leung, Caressa N. Spychala
Acinetobacter baumannii is a prevalent nosocomial pathogen with a high incidence of multidrug resistance. Treatment of infections due to this organism with colistin, a last-resort antibiotic of the polymyxin class, can result in the emergence of coli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9f64c18b035317f1a56e8feb2a611b
https://europepmc.org/articles/PMC6425172/
https://europepmc.org/articles/PMC6425172/
