Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Francesca Libonati"'
Autor:
Dimitrios Kouroupis, Carlotta Perucca Orfei, Diego Correa, Giuseppe Talò, Francesca Libonati, Paola De Luca, Vincenzo Raffo, Thomas M. Best, Laura de Girolamo
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 995 (2024)
Tendinopathies continue to be a challenge for both patients and the medical teams providing care as no universal clinical practice guidelines have been established. In general, tendinopathies are typically characterized by prolonged, localized, activ
Externí odkaz:
https://doaj.org/article/0263961295374a5e87ac7fa022a28f71
Autor:
Silvia Lopa, Francesca Libonati, Katia Mareschi, Giuseppe Talò, Stefania Brambilla, Vincenzo Raffo, Luciana Labanca, Luigi Zagra, Matteo Moretti, Laura de Girolamo, Alessandra Colombini
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 833 (2024)
Macrophage-based co-cultures are used to test the immunomodulatory function of candidate cells for clinical use. This study aimed to characterize a macrophage polarization model using human platelet lysate (hPL) as a GMP-compliant alternative to Feta
Externí odkaz:
https://doaj.org/article/69237daeb93549f6bb2996a2a63739e3
Inflammatory priming with IL-1β promotes the immunomodulatory behavior of adipose derived stem cells
Autor:
Alessandra Colombini, Francesca Libonati, Davide Cangelosi, Silvia Lopa, Paola De Luca, Domenico Antonio Coviello, Matteo Moretti, Laura de Girolamo
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Inflammatory processes contribute to osteoarthritis (OA) severity and progression. Mesenchymal stem cells, particularly those derived from adipose tissue (ASCs), are able to sense and control the inflammatory environment. This immunomodulatory potent
Externí odkaz:
https://doaj.org/article/bd2973dd16684f929ac724ca95d9f0a0
Autor:
Alessandra Colombini, Francesca Libonati, Silvia Lopa, Enrico Ragni, Paola De Luca, Luigi Zagra, Federico Sinigaglia, Matteo Moretti, Laura de Girolamo
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
The purpose of the present study is to predict by bioinformatics the activity of the extracellular vesicle (EV)-embedded micro RNA (miRNAs) secreted by cartilage cells (CCs), adipose tissue-derived- (ASCs), and bone marrow-derived stem cells (BMSCs)
Externí odkaz:
https://doaj.org/article/0edafc9b952e440ba4348cdbd7456fec
Autor:
Enrico Ragni, Andrea Papait, Carlotta Perucca Orfei, Antonietta Rosa Silini, Alessandra Colombini, Marco Viganò, Francesca Libonati, Ornella Parolini, Laura deGirolamo
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 7, Pp 1044-1062 (2021)
Abstract Human amniotic membrane‐derived mesenchymal stromal cells (hAMSCs) are easily obtained in large quantities and free from ethical concerns. Promising therapeutic results for both hAMSCs and their secreted factors (secretome) were described
Externí odkaz:
https://doaj.org/article/14c321ff07604eaea4507b2fc0468005
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15908 (2022)
Bone-marrow-mesenchymal-stromal-cells (BMSCs)- and platelet-rich-plasma (PRP)-based therapies have shown potential for treating osteoarthritis (OA). Recently, the combination of these two approaches was proposed, with results that overcame those obse
Externí odkaz:
https://doaj.org/article/c738cf409fd54178804eb5232546832c
Autor:
Enrico Ragni, Alessandra Colombini, Paola De Luca, Francesca Libonati, Marco Viganò, Carlotta Perucca Orfei, Luigi Zagra, Laura de Girolamo
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Cartilage cells (CCs), adipose tissue (ASC)- and bone marrow (BMSC)-derived mesenchymal stromal cells (MSCs) have been shown as promising candidates for the treatment of osteoarthritis (OA). Despite their adaptive ability, exposure to chronic catabol
Externí odkaz:
https://doaj.org/article/722a400cbd29485fa0dcec21abb19563
Autor:
Francesca Finetti, Nagaja Capitani, Noemi Manganaro, Vanessa Tatangelo, Francesca Libonati, Giulia Panattoni, Ivo Calaresu, Laura Ballerini, Cosima T. Baldari, Laura Patrussi
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
By preserving cell viability and three-dimensional localization, organotypic culture stands out among the newest frontiers of cell culture. It has been successfully employed for the study of diseases among which neoplasias, where tumoral cells take a
Externí odkaz:
https://doaj.org/article/2b433c885a91459f83940c0e93234e6d
Autor:
Alessandra Colombini, Enrico Ragni, Leonardo Mortati, Francesca Libonati, Carlotta Perucca Orfei, Marco Viganò, Marco Brayda-Bruno, Laura de Girolamo
Publikováno v:
Cells, Vol 10, Iss 5, p 1180 (2021)
The study of the miRNA cargo embedded in extracellular vesicles (EVs) released from adipose-derived mesenchymal stromal cells (ASC) preconditioned with IL-1β, an inflammatory stimulus driving osteoarthritis (OA), along with EVs-cartilage dynamic int
Externí odkaz:
https://doaj.org/article/0aed2efc54a8446791f4986bfd40de22
Autor:
Enrico Ragni, Alessandra Colombini, Marco Viganò, Francesca Libonati, Carlotta Perucca Orfei, Luigi Zagra, Laura de Girolamo
Publikováno v:
Cells, Vol 10, Iss 5, p 1072 (2021)
Intra-articular administration of adipose-derived mesenchymal stem cells (ASCs), either in vitro expanded or within adipose tissue-based products obtained at point-of-care, has gained popularity as innovative regenerative medicine approach for osteoa
Externí odkaz:
https://doaj.org/article/e78839c8e8024ed6b406f61d1b7fe739