Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Francesca Grillini"'
Autor:
Valentina Palermo, Sara Rinalducci, Massimo Sanchez, Francesca Grillini, Joshua A. Sommers, Robert M. Brosh, Lello Zolla, Annapaola Franchitto, Pietro Pichierri
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
End-resection of double strand DNA breaks is essential for pathway choice between non-homologous end-joining and homologous recombination. Here the authors show that phosphorylation of WRN helicase by CDK1 is essential for resection at replication-re
Externí odkaz:
https://doaj.org/article/c5a07e25c5d84b82a2f6c7c01fa3ba7f
Autor:
Valentina Palermo, Sara Rinalducci, Massimo Sanchez, Francesca Grillini, Annapaola Franchitto, Pietro Pichierri
Publikováno v:
Molecular & Cellular Oncology, Vol 4, Iss 1 (2017)
Replication-dependent double-strand breaks (DSBs) are the main source of genomic instability as their inaccurate repair stimulates chromosomal rearrangements. In a recent work, we uncover a novel regulatory circuit that involves the Werner's syndrome
Externí odkaz:
https://doaj.org/article/0f55fabeadbc4644b55b9f1d2818ead9
Autor:
Sara Rinalducci, Joshua A. Sommers, Robert M. Brosh, Francesca Grillini, Massimo Sanchez, Pietro Pichierri, Lello Zolla, Annapaola Franchitto, Valentina Palermo
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Regulation of end-processing is critical for accurate repair and to switch between homologous recombination (HR) and non-homologous end joining (NHEJ). End resection is a two-stage process but very little is known about regulation of the long-range r
Autor:
Sara Rinalducci, Annapaola Franchitto, Francesca Grillini, Massimo Sanchez, Pietro Pichierri, Valentina Palermo
Publikováno v:
Molecular & Cellular Oncology. 4:e1268243
Replication-dependent double-strand breaks (DSBs) are the main source of genomic instability as their inaccurate repair stimulates chromosomal rearrangements. In a recent work, we uncover a novel regulatory circuit that involves the Werner's syndrome