Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Francesca Grespi"'
Autor:
Margherita Zamberlan, Amandine Boeckx, Florian Muller, Federica Vinelli, Olivier Ek, Caterina Vianello, Emeline Coart, Keitaro Shibata, Aurélie Christian, Francesca Grespi, Marta Giacomello, Ingrid Struman, Luca Scorrano, Stéphanie Herkenne
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Mitochondrial fusion and fission proteins have been nominated as druggable targets in cancer. Whether their inhibition is efficacious in triple negative breast cancer (TNBC) that almost invariably develops chemoresistance is unkno
Externí odkaz:
https://doaj.org/article/ef5ee15a1b5a42608f6031e1dae86383
Autor:
Marta Zaninello, Konstantinos Palikaras, Deborah Naon, Keiko Iwata, Stephanie Herkenne, Ruben Quintana-Cabrera, Martina Semenzato, Francesca Grespi, Fred N. Ross-Cisneros, Valerio Carelli, Alfredo A. Sadun, Nektarios Tavernarakis, Luca Scorrano
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Autosomal dominant optic atrophy is caused by mutations in the mitochondrial fusion protein OPA1. Here, the authors show that AMPK-induced autophagy depletes mitochondria in axons of retinal ganglion cells and that autophagic inhibition reverses visi
Externí odkaz:
https://doaj.org/article/85cc1dcbdee340b78b661df3a14cc334
Publikováno v:
Biomolecules, Vol 12, Iss 4, p 567 (2022)
Gliomas are heterogeneous neoplasms, classified into grade I to IV according to their malignancy and the presence of specific histological/molecular hallmarks. The higher grade of glioma is known as glioblastoma (GB). Although progress has been made
Externí odkaz:
https://doaj.org/article/6b1f82402f614105a5cf43a18691b6a4
Autor:
Francesco Chemello, Francesca Grespi, Alessandra Zulian, Pasqua Cancellara, Etienne Hebert-Chatelain, Paolo Martini, Camilla Bean, Enrico Alessio, Lisa Buson, Martina Bazzega, Andrea Armani, Marco Sandri, Ruggero Ferrazza, Paolo Laveder, Graziano Guella, Carlo Reggiani, Chiara Romualdi, Paolo Bernardi, Luca Scorrano, Stefano Cagnin, Gerolamo Lanfranchi
Publikováno v:
Cell Reports, Vol 26, Iss 13, Pp 3784-3797.e8 (2019)
Summary: Skeletal muscle is composed of different myofiber types that preferentially use glucose or lipids for ATP production. How fuel preference is regulated in these post-mitotic cells is largely unknown, making this issue a key question in the fi
Externí odkaz:
https://doaj.org/article/f1aadd031b6e4843b189ce5480836280
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18051 (2011)
Different bacteria-derived systems for regulatable gene expression have been developed for the use in mammalian cells and some were also successfully adopted for in vivo use in vertebrate model organisms. However, certain limitations apply to most of
Externí odkaz:
https://doaj.org/article/0be1a431494a4a928a911e6aec14c651
Autor:
Luca Scorrano, Fred N. Ross-Cisneros, Alfredo A. Sadun, Martina Semenzato, Marta Zaninello, Francesca Grespi, Keiko Iwata, Konstantinos Palikaras, Ruben Quintana-Cabrera, Valerio Carelli, Stéphanie Herkenne, Deborah Naon, Nektarios Tavernarakis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
In autosomal dominant optic atrophy (ADOA), caused by mutations in the mitochondrial cristae biogenesis and fusion protein optic atrophy 1 (Opa1), retinal ganglion cell (RGC) dysfunction and visual loss occur by unknown mechanisms. Here, we show a ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b68d9d44bd5e9b6e0b873f2b8850afd
https://doaj.org/article/85cc1dcbdee340b78b661df3a14cc334
https://doaj.org/article/85cc1dcbdee340b78b661df3a14cc334
Autor:
Paolo Laveder, Alessandra Zulian, Andrea Armani, Paolo Martini, Gerolamo Lanfranchi, Lisa Buson, Marco Sandri, Francesca Grespi, Francesco Chemello, Paolo Bernardi, Camilla Bean, Graziano Guella, Enrico Alessio, Etienne Hebert-Chatelain, Ruggero Ferrazza, Stefano Cagnin, Carlo Reggiani, Chiara Romualdi, Luca Scorrano, Pasqua Cancellara, Martina Bazzega
Publikováno v:
Cell Reports, Vol 26, Iss 13, Pp 3784-3797.e8 (2019)
Summary: Skeletal muscle is composed of different myofiber types that preferentially use glucose or lipids for ATP production. How fuel preference is regulated in these post-mitotic cells is largely unknown, making this issue a key question in the fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::471c2693984cdb43ce26771362b121d5
http://www.sciencedirect.com/science/article/pii/S2211124719302918
http://www.sciencedirect.com/science/article/pii/S2211124719302918
Autor:
Gerolamo Lanfranchi, Stefano Cagnin, Maria Lina Massimino, Chiara Romualdi, Beniamina Pacchioni, Francesco Chemello, Paolo Martini, Caterina Millino, Alessandro Bertoli, Luca Scorrano, Enrico Alessio, Caterina Peggion, Lisa Buson, Francesca Grespi
Publikováno v:
Nucleic Acids Research
Long non-coding RNAs (lncRNAs) are emerging as important players in the regulation of several aspects of cellular biology. For a better comprehension of their function, it is fundamental to determine their tissue or cell specificity and to identify t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e552f7520b3d550ba9547edda77eb3b4
http://hdl.handle.net/11379/533928
http://hdl.handle.net/11379/533928
Autor:
Ruggero Ferrazza, Paolo Martini, Graziano Guella, Luca Scorrano, Francesco Chemello, Francesca Grespi, Carlo Reggiani, Paolo Laveder, Alessandra Zulian, Gerolamo Lanfranchi, Paolo Bernardi, Pasqua Cancellara, Chiara Romualdi, Etienne Hebert-Chatelain, Camilla Bean, Enrico Alessio, Stefano Cagnin
SUMMARYSkeletal muscle is composed by different myofiber types that can preferentially use glycolysis or lipids for ATP production. How fuel preference is specified in these post-mitotic cells is unknown. Here we show that miRNAs are important player
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c861a2eb382d0c39a2cd8154949bad
Autor:
Tatiana Varanita, Diego De Stefani, María Isabel Hernández-Alvarez, Luca Scorrano, Sowmya Lakshminaranayan, Deborah Naon, Antonio Zorzano, Stéphanie Herkenne, Francesca Grespi, Marta Giacomello, Martina Semenzato, Marta Zaninello, Annalisa Serafini, Gerald W. Dorn
Publikováno v:
Proceedings of the National Academy of Sciences. 114
We thank Filadi et al. for their comments (1) on our paper (2), where we address whether the discrepancies between their paper (3) and our original discovery of Mitofusin (Mfn) 2 as an endoplasmic reticulum (ER)–mitochondria tether (4) resulted fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7c30e556a534312b71f00dcf9e1670
https://doi.org/10.1073/pnas.1618610114
https://doi.org/10.1073/pnas.1618610114