Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Francesca Galeffi"'
Publikováno v:
Brain Stimulation, Vol 14, Iss 1, Pp 80-87 (2021)
Background: Transcranial electrical stimulation at an appropriate dose may demonstrate intracranial effects, including neuronal stimulation and cerebral blood flow responses. Objective: We performed in vivo experiments on mouse cortex using transcran
Externí odkaz:
https://doaj.org/article/fea66b5b0e6440d7b7422f5cd26d8206
Publikováno v:
Neurobiology of Disease, Vol 62, Iss , Pp 469-478 (2014)
Prolonged hypoxia leads to irreversible loss of neuronal function and metabolic impairment of nicotinamide adenine dinucleotide recycling (between NAD+ and NADH) immediately after reoxygenation, resulting in NADH hyperoxidation. We test whether the a
Externí odkaz:
https://doaj.org/article/818573e3dd0f41a3b4eadc1d66850aff
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 1, Pp 177-187 (2012)
The use of energy substrates, such as lactate and pyruvate, has been shown to improve synaptic function when administered during glucose deprivation. In the present study, we investigated whether prolonged incubation with monocarboxylate (pyruvate or
Externí odkaz:
https://doaj.org/article/a21d995e922841c0a17413770234dbc9
Autor:
Sarah E Wetzel-Strong, Francesca Galeffi, Christian Benavides, Mary Patrucco, Jessica L Bullock, Carol J Gallione, Han Kyu Lee, Douglas A Marchuk
Publikováno v:
GENETICS.
Sturge–Weber Syndrome (SWS) is a sporadic (non-inherited) syndrome characterized by capillary vascular malformations in the facial skin, leptomeninges, or the choroid. A hallmark feature is the mosaic nature of the phenotype. SWS is caused by a som
Publikováno v:
Brain Stimulation, Vol 14, Iss 1, Pp 80-87 (2021)
Brain Stimul
Brain Stimul
BACKGROUND: Transcranial electrical stimulation at an appropriate dose may demonstrate intracranial effects, including neuronal stimulation and cerebral blood flow responses. OBJECTIVE: We performed in vivo experiments on mouse cortex using transcran
Autor:
Huaxin Sheng, Jingjun Lyu, Francesca Galeffi, Dennis A. Turner, Wulf Paschen, Zhuoran Wang, Joshua D. Bernstock, Yuntian Shen, Shu Yu, Shuai Liu, Wei Yang, Ramona M. Rodriguiz, Kory R. Johnson, Ran Li, William C. Wetsel
Publikováno v:
FASEB J
Small ubiquitin-like modifier (SUMO1–3) conjugation (SUMOylation), a post-translational modification, modulates almost all major cellular processes. Mounting evidence indicates that SUMOylation plays a crucial role in maintaining and regulating neu
Autor:
Francesca Galeffi, Ya-chao Wang, Xuan Li, Wei Wang, Wei Yang, Huaxin Sheng, Ulrike Hoffmann, Dennis A. Turner, Liping Lu
Publikováno v:
Exp Neurol
Background and purpose Ischemic stroke significantly perturbs neuronal homeostasis leading to a cascade of pathologic events causing brain damage. In this study, we assessed acute stroke outcome after chemogenetic inhibition of forebrain excitatory n
Publikováno v:
Neurobiology of Aging. 36:982-992
Previous reports have indicated that with aging, intrinsic brain tissue changes in cellular bioenergetics may hamper the brain's ability to cope with metabolic stress. Therefore, we analyzed the effects of age on neuronal sensitivity to glucose depri
Publikováno v:
Neurobiology of Disease, Vol 62, Iss, Pp 469-478 (2014)
Prolonged hypoxia leads to irreversible loss of neuronal function and metabolic impairment of nicotinamide adenine dinucleotide recycling (between NAD(+) and NADH) immediately after reoxygenation, resulting in NADH hyperoxidation. We test whether the
Publikováno v:
Journal of Neurochemistry. 81:108-111
We have shown that diazepam (DZ) protects hippocampal neurons when administered early after transient cerebral ischemia. To examine mechanisms of DZ action, in the absence of systemic effects, we used an in vitro model of ischemia [oxygen-glucose dep