Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Francesca Froldi"'
Autor:
Kellie Veen, Phuong‐Khanh Nguyen, Francesca Froldi, Qian Dong, Edel Alvarez‐Ochoa, Kieran F Harvey, John PD McMullen, Owen Marshall, Patricia R Jusuf, Louise Y Cheng
Publikováno v:
EMBO reports.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01832e67261854fc1596f9d4a4348b09
https://doi.org/10.15252/embr.202255837
https://doi.org/10.15252/embr.202255837
Autor:
Joseph H.A. Vissers, Francesca Froldi, Jan Schröder, Anthony T. Papenfuss, Louise Y. Cheng, Kieran F. Harvey
Publikováno v:
Cell Reports, Vol 25, Iss 6, Pp 1561-1576.e7 (2018)
Summary: The ability of cells to stably maintain their fate is governed by specific transcription regulators. Here, we show that the Scalloped (Sd) and Nervous fingers-1 (Nerfin-1) transcription factors physically and functionally interact to maintai
Externí odkaz:
https://doaj.org/article/d06dc6f98d644b46807f884ebc9b40e0
Publikováno v:
AIMS Genetics, Vol 2, Iss 1, Pp 13-24 (2015)
In the developing Drosophila CNS, two pools of neural stem cells, the symmetrically dividing progenitors in the neuroepithelium (NE) and the asymmetrically dividing neuroblasts (NBs) generate the majority of the neurons that make up the adult central
Externí odkaz:
https://doaj.org/article/aece5fbea6af4166868585937b0bad71
Autor:
Kellie Veen, Francesca Froldi, Qian Dong, Edel Alvarez-Ochoa, Phuong-Khanh Nguyen, Kieran F Harvey, John P D McMullen, Owen Marshall, Patricia R Jusuf, Louise Y Cheng
Dedifferentiation is the reversion of differentiated cells to a stem cell like fate, whereby, the gene expression program of mature cells is altered and genes associated with multipotency are expressed. Appropriate terminal differentiation of NSCs is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ff33a9b7f46e6c6d05741470aaabd32
https://doi.org/10.1101/2022.07.24.501087
https://doi.org/10.1101/2022.07.24.501087
Glial Hedgehog signalling and lipid metabolism regulate neural stem cell proliferation in Drosophila
Publikováno v:
EMBO Rep
The final size and function of the adult central nervous system (CNS) are determined by neuronal lineages generated by neural stem cells (NSCs) in the developing brain. In Drosophila, NSCs called neuroblasts (NBs) reside within a specialised microenv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e00cae66a627876f2a82dfffdde50f3
https://doi.org/10.15252/embr.202052130
https://doi.org/10.15252/embr.202052130
Cancer cells contribute to distinct malignant traits depending on their MYC and pJNK relative levels
Clonal analysis is common practice in Drosophila. In particular, induction of cell clusters carrying either loss-of-function alleles of neoplastic tumour suppressors or activated forms of oncogenes has successfully been exploited to study cooperative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6b94d5623a7802b4d897049c98e59ff6
http://hdl.handle.net/11585/700029
http://hdl.handle.net/11585/700029
Autor:
Sofia Golenkina, Ronnie Blazev, Louise Y. Cheng, Michael Zavortink, Verena Wimmer, Benjamin L. Parker, Daniel Bakopoulos, Elizabeth L. Christie, William Lodge, Callum Dark, Shane Cheung, Brigette C. Duckworth, Francesca Froldi, Helena E. Richardson
Publikováno v:
Developmental cell. 56(18)
Cachexia, the wasting syndrome commonly observed in advanced cancer patients, accounts for up to one-third of cancer-related mortalities. We have established a Drosophila larval model of organ wasting whereby epithelial overgrowth in eye-antennal dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f5161f8514e567f1f8977d793b182f
https://pubmed.ncbi.nlm.nih.gov/34473940
https://pubmed.ncbi.nlm.nih.gov/34473940
Publikováno v:
Wiley interdisciplinary reviews. Developmental biologyREFERENCES. 10(4)
Studies in model organisms have demonstrated that extensive communication occurs between distant organs both during development and in diseases such as cancer. Organs communicate with each other to coordinate growth and reach the correct size, while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a627b27fc9cbed1759f77ed3a5c3a799
https://pubmed.ncbi.nlm.nih.gov/32852143
https://pubmed.ncbi.nlm.nih.gov/32852143
Summary The final size of the adult central nervous system (CNS) is determined by the size of neuronal lineages generated by neural stem cells (NSCs) during development. In Drosophila, NSCs called neuroblasts (NBs) reside within a specialised microen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b6dc90b541355f6ceb9cc5937562235
https://doi.org/10.1101/2020.05.18.100990
https://doi.org/10.1101/2020.05.18.100990