Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Francesca Forti"'
Autor:
Ravi K. Lokareddy, Chun-Feng David Hou, Francesca Forti, Stephano M. Iglesias, Fenglin Li, Mikhail Pavlenok, David S. Horner, Michael Niederweis, Federica Briani, Gino Cingolani
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract DEV is an obligatory lytic Pseudomonas phage of the N4-like genus, recently reclassified as Schitoviridae. The DEV genome encodes 91 ORFs, including a 3398 amino acid virion-associated RNA polymerase (vRNAP). Here, we describe the complete a
Externí odkaz:
https://doaj.org/article/f0520421212b4ab68758fafb4b4c926f
Autor:
Federica A. Falchi, Francesca Forti, Cristina Carnelli, Aurelia Genco, Roberto Pizzoccheri, Caterina Manzari, Giulio Pavesi, Federica Briani
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Polyribonucleotide phosphorylase (PNPase) is a phosphorolytic RNA exonuclease highly conserved throughout evolution. In Escherichia coli, PNPase controls complex phenotypic traits like biofilm formation and growth at low temperature. In huma
Externí odkaz:
https://doaj.org/article/e47628bfe78d4ba68a67b8f67040857a
Autor:
Fenglin Li, Chun-Feng David Hou, Ravi K. Lokareddy, Ruoyu Yang, Francesca Forti, Federica Briani, Gino Cingolani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract E217 is a Pseudomonas phage used in an experimental cocktail to eradicate cystic fibrosis-associated Pseudomonas aeruginosa. Here, we describe the structure of the whole E217 virion before and after DNA ejection at 3.1 Å and 4.5 Å resoluti
Externí odkaz:
https://doaj.org/article/38133d6530e84a9d861168e041548fd0
Autor:
Francesca Forti, Claudia Bertoli, Marco Cafora, Sara Gilardi, Anna Pistocchi, Federica Briani
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Phage therapy represents a promising strategy for curing bacterial infections refractory to antibiotics. However, the success rate of phage therapy may be lowered by the emergence of bacterial resistance to the phages used for therapy. In th
Externí odkaz:
https://doaj.org/article/23dbef7b5ee04e55b332fc657aa143c6
Autor:
Marco Cafora, Noemi Poerio, Francesca Forti, Nicoletta Loberto, Davide Pin, Rosaria Bassi, Massimo Aureli, Federica Briani, Anna Pistocchi, Maurizio Fraziano
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Multi drug resistant (MDR) bacteria are insensitive to the most common antibiotics currently in use. The spread of antibiotic-resistant bacteria, if not contained, will represent the main cause of death for humanity in 2050. The situation is even mor
Externí odkaz:
https://doaj.org/article/381f8ec2e51e4526a1525df4727771a7
Autor:
Thomas Carzaniga, Federica A. Falchi, Francesca Forti, Davide Antoniani, Paolo Landini, Federica Briani
Publikováno v:
Microorganisms, Vol 9, Iss 5, p 1010 (2021)
Escherichia coli C is a strong biofilm producer in comparison to E. coli K-12 laboratory strains due to higher expression of the pgaABCD operon encoding the enzymes for the biosynthesis of the extracellular polysaccharide poly-β-1,6-N-acetylglucosam
Externí odkaz:
https://doaj.org/article/4f0887cf4f1b4383a112e2b5614a5a77
Autor:
Federica A. Falchi, Flaviana Di Lorenzo, Roberto Pizzoccheri, Gianluca Casino, Moira Paroni, Francesca Forti, Antonio Molinaro, Federica Briani
Publikováno v:
Microorganisms, Vol 8, Iss 6, p 826 (2020)
LpxT is an inner membrane protein that transfers a phosphate group from the essential lipid undecaprenyl pyrophosphate (C-55PP) to the lipid A moiety of lipopolysaccharide, generating a lipid A tris-phosphorylated species. The protein is encoded by t
Externí odkaz:
https://doaj.org/article/245046b5609042eb8cd603b840aaf9c4
Autor:
Obolbek Turapov, Francesca Forti, Baleegh Kadhim, Daniela Ghisotti, Jad Sassine, Anna Straatman-Iwanowska, Andrew R. Bottrill, Patrick J. Moynihan, Russell Wallis, Philippe Barthe, Martin Cohen-Gonsaud, Paul Ajuh, Waldemar Vollmer, Galina V. Mukamolova
Publikováno v:
Cell Reports, Vol 25, Iss 1, Pp 57-67.e5 (2018)
Summary: Tuberculosis claims >1 million lives annually, and its causative agent Mycobacterium tuberculosis is a highly successful pathogen. Protein kinase B (PknB) is reported to be critical for mycobacterial growth. Here, we demonstrate that PknB-de
Externí odkaz:
https://doaj.org/article/4e08d52c900c43d28b697f1337d6c302
Autor:
Obolbek Turapov, Jessica Loraine, Christopher H. Jenkins, Philippe Barthe, Daniel McFeely, Francesca Forti, Daniela Ghisotti, Dusan Hesek, Mijoon Lee, Andrew R. Bottrill, Waldemar Vollmer, Shahriar Mobashery, Martin Cohen-Gonsaud, Galina V. Mukamolova
Publikováno v:
Open Biology, Vol 5, Iss 7 (2015)
PknB is an essential serine/threonine protein kinase required for mycobacterial cell division and cell-wall biosynthesis. Here we demonstrate that overexpression of the external PknB_PASTA domain in mycobacteria results in delayed regrowth, accumulat
Externí odkaz:
https://doaj.org/article/769d10a9bca946cdb71d9703183953f2
Autor:
Paolo Miotto, Francesca Forti, Alessandro Ambrosi, Danilo Pellin, Diogo F Veiga, Gabor Balazsi, Maria L Gennaro, Clelia Di Serio, Daniela Ghisotti, Daniela M Cirillo
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51950 (2012)
Only few small RNAs (sRNAs) have been characterized in Mycobacterium tuberculosis and their role in regulatory networks is still poorly understood. Here we report a genome-wide characterization of sRNAs in M. tuberculosis integrating experimental and
Externí odkaz:
https://doaj.org/article/807f5aa603544be88cf3e2ea6fdab75a