Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Francesca Faggioli"'
Publikováno v:
Cells, Vol 12, Iss 6, p 860 (2023)
Metastasis is a systemic condition and the major challenge among cancer types, as it can lead to multiorgan vulnerability. Recently, attention has been drawn to cellular senescence, a complex stress response condition, as a factor implicated in metas
Externí odkaz:
https://doaj.org/article/992ef65f64904f319a05ddf55b0e5f70
Autor:
Tui Neri, Sharon Muggeo, Marianna Paulis, Maria Elena Caldana, Laura Crisafulli, Dario Strina, Maria Luisa Focarelli, Francesca Faggioli, Camilla Recordati, Samantha Scaramuzza, Eugenio Scanziani, Stefano Mantero, Chiara Buracchi, Cristina Sobacchi, Angelo Lombardo, Luigi Naldini, Paolo Vezzoni, Anna Villa, Francesca Ficara
Publikováno v:
Stem Cell Reports, Vol 5, Iss 4, Pp 558-568 (2015)
Autosomal recessive osteopetrosis is a human bone disease mainly caused by TCIRG1 gene mutations that prevent osteoclasts resorbing activity, recapitulated by the oc/oc mouse model. Bone marrow transplantation is the only available treatment, limited
Externí odkaz:
https://doaj.org/article/647f9e54a0b446388f71402cf3173ba1
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26080 (2011)
Polyploidization is the most well recognized feature of the liver. Yet, a quantitative and behavioral analysis of centrosomes and DNA content in normal hepatocytes has been limited by the technical challenges of methods available. By using a novel ap
Externí odkaz:
https://doaj.org/article/81bf30942f9048c29ef8c69c7f0a552a
Autor:
Ombretta Garbarino, Luca Lambroia, Gianluca Basso, Veronica Marrella, Barbara Franceschini, Cristiana Soldani, Fabio Pasqualini, Desiree Giuliano, Guido Costa, Clelia Peano, Davide Barbarossa, Destro Annarita, Andreina Salvati, Luigi Terracciano, Guido Torzilli, Matteo Donadon, Francesca Faggioli
Publikováno v:
Aging Cell.
Autor:
Michela Lizier, Alessandra Castelli, Cristina Montagna, Franco Lucchini, Paolo Vezzoni, Francesca Faggioli
Publikováno v:
World Journal of Hepatology
There is wide agreement that cell fusion is a physiological process in cells in mammalian bone, muscle and placenta. In other organs, such as the cerebellum, cell fusion is controversial. The liver contains a considerable number of polyploid cells: T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237430f0f1a33aecba5c62cb0f3c37b7
http://hdl.handle.net/10807/125363
http://hdl.handle.net/10807/125363
Autor:
Paolo Vezzoni, Anna Villa, Matteo Donadon, Luca Di Tommaso, Veronica Marrella, Barbara Cassani, Francesca Faggioli, Camilla Recordati, Stefano Mantero, Eleonora Palagano
Publikováno v:
Hepatology (Baltimore, Md.). 67(5)
Hepatocellular carcinoma (HCC) is a frequent neoplasia and a leading cause of inflammation-related cancer mortality. Despite most HCC arise from persistent inflammatory conditions; pathways linking chronic inflammation to cancer development are still
Autor:
Cristina Montagna, Francesca Faggioli, Jan Vijg, Wanxia Li Tsai, Judith Campisi, Grasiella A. Andriani, Maurizio Mauro, Vinnycius Pereira Almeida, Laura Santambrogio, Massimo Gadina, Alexander Y. Maslov
Publikováno v:
Scientific Reports
Scientific reports, vol 6, iss 1
Andriani, GA; Almeida, VP; Faggioli, F; Mauro, M; Li Tsai, W; Santambrogio, L; et al.(2016). Whole chromosome instability induces senescence and promotes SASP. Scientific Reports, 6. doi: 10.1038/srep35218. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/75p4v4dw
Scientific reports, vol 6, iss 1
Andriani, GA; Almeida, VP; Faggioli, F; Mauro, M; Li Tsai, W; Santambrogio, L; et al.(2016). Whole chromosome instability induces senescence and promotes SASP. Scientific Reports, 6. doi: 10.1038/srep35218. Lawrence Berkeley National Laboratory: Lawrence Berkeley National Laboratory. Retrieved from: http://www.escholarship.org/uc/item/75p4v4dw
Age-related accumulation of ploidy changes is associated with decreased expression of genes controlling chromosome segregation and cohesin functions. To determine the consequences of whole chromosome instability (W-CIN) we down-regulated the spindle
Publikováno v:
Human Molecular Genetics. 21:5246-5253
Chromosomal aneuploidy, the gain or loss of whole chromosomes, is a hallmark of pathological conditions and a causal factor of birth defects and cancer. A number of studies indicate that aneuploid cells are present at a high frequency in the brain of
Publikováno v:
Mechanisms of Ageing and Development. 132:429-436
Mechanisms that govern genome integrity and stability are major guarantors of viability and longevity. As people age, memory and the ability to carry out tasks often decline and their risk for neurodegenerative diseases increases. The biological mech
Publikováno v:
Journal of Medicinal Chemistry. 50:6274-6278
The inclusion of poly(ethylene glycol) monolaurate in liposomes formulated with dimyristoyl-sn-glycero-3-phosphocholine and certain cationic gemini surfactants improves their capability of condensing DNA into a psi phase and transfecting it into cell