Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Francesca E, Duncan"'
Autor:
Emily J. Zaniker, Jiyang Zhang, Daniela Russo, Ruixu Huang, Kristine Suritis, Riley S. Drake, Esther Barlow-Smith, Alex K. Shalek, Teresa K. Woodruff, Shuo Xiao, Brittany A. Goods, Francesca E. Duncan
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-23 (2024)
Abstract During ovulation, the apical wall of the preovulatory follicle breaks down to facilitate gamete release. In parallel, the residual follicle wall differentiates into a progesterone-producing corpus luteum. Disruption of ovulation, whether thr
Externí odkaz:
https://doaj.org/article/422a5bda6fd7443eb783b07c2b18ee4b
Autor:
Ewa K Bomba-Warczak, Karen M Velez, Luhan T Zhou, Christelle Guillermier, Seby Edassery, Matthew L Steinhauser, Jeffrey N Savas, Francesca E Duncan
Publikováno v:
eLife, Vol 13 (2024)
The mechanisms contributing to age-related deterioration of the female reproductive system are complex, however aberrant protein homeostasis is a major contributor. We elucidated exceptionally stable proteins, structures, and macromolecules that pers
Externí odkaz:
https://doaj.org/article/6aa92de16b3c4bd9af87d1fb9f1b6b64
Autor:
Amrita Salvi, Wenping Li, Shweta S. Dipali, Stephanie M. Cologna, Mary Ellen Pavone, Francesca E. Duncan, Joanna E. Burdette
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27336- (2024)
Ovarian cancer (OC) is deadly, and likely arises from the fallopian tube epithelium (FTE). Despite the association of OC with ovulation, OC typically presents in post-menopausal women who are no longer ovulating. The goal of this study was to underst
Externí odkaz:
https://doaj.org/article/49d8898c148c4c59bd7b3ae8ae9f6e78
Autor:
Emily J. Zaniker, Prianka H. Hashim, Samuel Gauthier, James A. Ankrum, Hannes Campo, Francesca E. Duncan
Publikováno v:
Bioengineering, Vol 11, Iss 7, p 719 (2024)
Ex vivo follicle growth is an essential tool, enabling interrogation of folliculogenesis, ovulation, and luteinization. Though significant advancements have been made, existing follicle culture strategies can be technically challenging and laborious.
Externí odkaz:
https://doaj.org/article/6ff402beb4804f5f9dddbed03f6316ea
Autor:
Rosalba Perrone, Prasanna Vadhana Ashok Kumaar, Lauren Haky, Cosmo Hahn, Rebeccah Riley, Julia Balough, Giuliana Zaza, Bikem Soygur, Kaitlyn Hung, Leandro Prado, Herbert G. Kasler, Ritesh Tiwari, Hiroyuki Matsui, Genesis Vega Hormazabal, Indra Heckenbach, Morten Scheibye-Knudsen, Francesca E. Duncan, Eric Verdin
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107949- (2023)
Summary: Mammalian female reproductive lifespan is typically significantly shorter than life expectancy and is associated with a decrease in ovarian NAD+ levels. However, the mechanisms underlying this loss of ovarian NAD+ are unclear. Here, we show
Externí odkaz:
https://doaj.org/article/b684e354f37142c3801059b7ca25046d
Autor:
Maria E. Cinzori, Diana C. Pacyga, Elnur Babayev, Francesca E. Duncan, Zhong Li, Paige L. Williams, Jodi A. Flaws, Rita S. Strakovsky
Publikováno v:
Environment International, Vol 172, Iss , Pp 107771- (2023)
Background/objectives: Women are ubiquitously exposed to endocrine disruptors, including phthalates. Ovarian follicles undergoing folliculogenesis (indirectly measured by ovarian volume) produce anti-Müllerian hormone (AMH) and estradiol (E2). We ev
Externí odkaz:
https://doaj.org/article/a175657c87f94217a45f32d07ab913c6
Autor:
Miguel Angel Brieño-Enriquez, Francesca E. Duncan, Arjumand Ghazi, Michael Klutstein, Vittorio Sebastiano, Jessica Tyler
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/2937b91e6a4a44d69446dc320dee1efc
Autor:
Atsuko Kusuhara, Elnur Babayev, Luhan T. Zhou, Vijay P. Singh, Jennifer L. Gerton, Francesca E. Duncan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Egg quality dictates fertility outcomes, and although there is a well-documented decline with advanced reproductive age, how it changes during puberty is less understood. Such knowledge is critical, since advances in Assisted Reproductive Technologie
Externí odkaz:
https://doaj.org/article/43799be5c875431cbc20a55f88ad5b9f
Autor:
Shweta S. Dipali, Christina R. Ferreira, Luhan T. Zhou, Michele T. Pritchard, Francesca E. Duncan
Publikováno v:
Reproductive Biology and Endocrinology, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Background Reproductive aging is a robust phenotype that occurs in all females and is characterized by a significant reduction in gamete quantity and quality, which can have negative consequences on both endocrine function and fertility. Age
Externí odkaz:
https://doaj.org/article/6c0b3e78de6343e282fbf6a877455f20
Autor:
Qinan Hu, Francesca E. Duncan, Andrew B. Nowakowski, Olga A. Antipova, Teresa K. Woodruff, Thomas V. O'Halloran, Mariana F. Wolfner
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101275- (2020)
Summary: Temporal fluctuations in zinc concentration are essential signals, including during oogenesis and early embryogenesis. In mammals, zinc accumulation and release are required for oocyte maturation and egg activation, respectively. Here, we de
Externí odkaz:
https://doaj.org/article/3d9d031f0a8a4ec59f97d7b0ba062250