Zobrazeno 1 - 10
of 2 136
pro vyhledávání: '"Francesca E"'
Autor:
Emily J. Zaniker, Jiyang Zhang, Daniela Russo, Ruixu Huang, Kristine Suritis, Riley S. Drake, Esther Barlow-Smith, Alex K. Shalek, Teresa K. Woodruff, Shuo Xiao, Brittany A. Goods, Francesca E. Duncan
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-23 (2024)
Abstract During ovulation, the apical wall of the preovulatory follicle breaks down to facilitate gamete release. In parallel, the residual follicle wall differentiates into a progesterone-producing corpus luteum. Disruption of ovulation, whether thr
Externí odkaz:
https://doaj.org/article/422a5bda6fd7443eb783b07c2b18ee4b
Autor:
Ewa K Bomba-Warczak, Karen M Velez, Luhan T Zhou, Christelle Guillermier, Seby Edassery, Matthew L Steinhauser, Jeffrey N Savas, Francesca E Duncan
Publikováno v:
eLife, Vol 13 (2024)
The mechanisms contributing to age-related deterioration of the female reproductive system are complex, however aberrant protein homeostasis is a major contributor. We elucidated exceptionally stable proteins, structures, and macromolecules that pers
Externí odkaz:
https://doaj.org/article/6aa92de16b3c4bd9af87d1fb9f1b6b64
Autor:
Samantha Walczuk, Francesca E. Cunningham, Xinhua Zhao, Diane Dong, Peter A. Glassman, Donald R. Miller, Deborah Khachikian, Anthony Au, Cedric Salone, Kelly Bryan, Qoua Her, Sherrie L. Aspinall
Publikováno v:
Pharmacoepidemiology, Vol 3, Iss 1, Pp 103-116 (2024)
We described insulin glargine (originator) and insulin glargine-yfgn (biosimilar) treatment patterns, assessed effectiveness and safety outcomes, and identified reasons for switching back to the originator product from the biosimilar. This retrospect
Externí odkaz:
https://doaj.org/article/a298ba3cf45d4a1b980727b718f42035
Autor:
Amrita Salvi, Wenping Li, Shweta S. Dipali, Stephanie M. Cologna, Mary Ellen Pavone, Francesca E. Duncan, Joanna E. Burdette
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27336- (2024)
Ovarian cancer (OC) is deadly, and likely arises from the fallopian tube epithelium (FTE). Despite the association of OC with ovulation, OC typically presents in post-menopausal women who are no longer ovulating. The goal of this study was to underst
Externí odkaz:
https://doaj.org/article/49d8898c148c4c59bd7b3ae8ae9f6e78
Autor:
Emily J. Zaniker, Prianka H. Hashim, Samuel Gauthier, James A. Ankrum, Hannes Campo, Francesca E. Duncan
Publikováno v:
Bioengineering, Vol 11, Iss 7, p 719 (2024)
Ex vivo follicle growth is an essential tool, enabling interrogation of folliculogenesis, ovulation, and luteinization. Though significant advancements have been made, existing follicle culture strategies can be technically challenging and laborious.
Externí odkaz:
https://doaj.org/article/6ff402beb4804f5f9dddbed03f6316ea
Autor:
Rosalba Perrone, Prasanna Vadhana Ashok Kumaar, Lauren Haky, Cosmo Hahn, Rebeccah Riley, Julia Balough, Giuliana Zaza, Bikem Soygur, Kaitlyn Hung, Leandro Prado, Herbert G. Kasler, Ritesh Tiwari, Hiroyuki Matsui, Genesis Vega Hormazabal, Indra Heckenbach, Morten Scheibye-Knudsen, Francesca E. Duncan, Eric Verdin
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107949- (2023)
Summary: Mammalian female reproductive lifespan is typically significantly shorter than life expectancy and is associated with a decrease in ovarian NAD+ levels. However, the mechanisms underlying this loss of ovarian NAD+ are unclear. Here, we show
Externí odkaz:
https://doaj.org/article/b684e354f37142c3801059b7ca25046d
Autor:
Francesca E. Mowry, Francisco Espejo-Porras, Shijie Jin, Zainuddin Quadri, Limin Wu, Marcela Bertolio, Rachel Jarvis, Caroline Reynolds, Rashed Alananzeh, Erhard Bieberich, Yongjie Yang
Publikováno v:
Neurobiology of Disease, Vol 184, Iss , Pp 106213- (2023)
Female biased pathology and cognitive decline in Alzheimer's disease (AD) have been consistently observed with unclear underlying mechanisms. Although brain sphingolipid ceramide is elevated in AD patients, whether and how ceramide may contribute to
Externí odkaz:
https://doaj.org/article/509fb612939a4183a6b3cf0401ff8325
Autor:
Jessica Eloso, Asma Awad, Xinhua Zhao, Francesca E. Cunningham, Rongping Zhang, Diane Dong, Cathy Kelley, Peter A. Glassman, Sherrie L. Aspinall
Publikováno v:
American Journal of Medicine Open, Vol 9, Iss , Pp 100035- (2023)
Background: Real-world data on use of PCSK9 inhibitors (PCSK9-Is), with or without statins and/or ezetimibe, and associated outcomes, can inform more effective prescribing. The objective was to evaluate clinical effectiveness and safety of PCSK9-Is w
Externí odkaz:
https://doaj.org/article/50087d164f544a1eb20182833c0489fa
Autor:
Sunao Hasegawa, Michaël Marsset, Francesca E. DeMeo, Josef Hanuš, Richard P. Binzel, Schelte J. Bus, Brian Burt, David Polishook, Cristina A. Thomas, Jooyeon Geem, Masateru Ishiguro, Daisuke Kuroda, Pierre Vernazza
Publikováno v:
The Astronomical Journal, Vol 167, Iss 5, p 224 (2024)
Large terrestrial bodies in our solar system like the Earth, Mars, Mercury, and the Moon exhibit geologically complex surfaces with compositional heterogeneity. From past studies using large telescopes and spacecraft, it was shown that asteroids with
Externí odkaz:
https://doaj.org/article/5e3f681a210e49f1900c43d3e9ccff8c
Autor:
Maria E. Cinzori, Diana C. Pacyga, Elnur Babayev, Francesca E. Duncan, Zhong Li, Paige L. Williams, Jodi A. Flaws, Rita S. Strakovsky
Publikováno v:
Environment International, Vol 172, Iss , Pp 107771- (2023)
Background/objectives: Women are ubiquitously exposed to endocrine disruptors, including phthalates. Ovarian follicles undergoing folliculogenesis (indirectly measured by ovarian volume) produce anti-Müllerian hormone (AMH) and estradiol (E2). We ev
Externí odkaz:
https://doaj.org/article/a175657c87f94217a45f32d07ab913c6