Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Francesca Demarchi"'
Autor:
Elena Marcassa, Marzia Raimondi, Tahira Anwar, Eeva-Liisa Eskelinen, Michael P. Myers, Gianluca Triolo, Claudio Schneider, Francesca Demarchi
Publikováno v:
Biology Open, Vol 6, Iss 5, Pp 551-562 (2017)
CAPNS1 is essential for stability and function of the ubiquitous calcium-dependent proteases micro- and milli-calpain. Upon inhibition of the endoplasmic reticulum Ca2+ ATPase by 100 nM thapsigargin, both micro-calpain and autophagy are activated in
Externí odkaz:
https://doaj.org/article/aded7b946ff2430f928ef4cf84261e29
Autor:
Ilenia Pellarin, Laura Arnoldo, Silvia Costantini, Silvia Pegoraro, Gloria Ros, Carlotta Penzo, Gianluca Triolo, Francesca Demarchi, Riccardo Sgarra, Alessandro Vindigni, Guidalberto Manfioletti
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164258 (2016)
The HMGA1 architectural transcription factor is an oncogene overexpressed in the vast majority of human cancers. HMGA1 is a highly connected node in the nuclear molecular network and the key aspect of HMGA1 involvement in cancer development is that H
Externí odkaz:
https://doaj.org/article/98cf51b3a6874e88a45dea82f8a0574e
Autor:
Francesco La Marra, Francesca Demarchi, Marzia Raimondi, Claudio Schneider, Daniela Cesselli, Carla Di Loreto
Publikováno v:
Autophagy. 15(4)
ULK1 (unc-51 like autophagy activating kinase 1) is a core component at multiple steps of canonical macroautophagy/autophagy. The activity of ULK1 is tightly regulated by several post-translational modifications, including ubiquitination, yet the deu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b97cfcddd553b07d70b303c67f01dec9
https://pubmed.ncbi.nlm.nih.gov/30335599
https://pubmed.ncbi.nlm.nih.gov/30335599
Autor:
Ramiro Mendoza-Maldonado, Marzia Raimondi, T Arnandis, M Bestagno, E Marcassa, Francesca Demarchi, Claudio Schneider, Francesca Cataldo
Publikováno v:
CELL CYCLE
CAPNS1 is essential for the stability and function of ubiquitous CAPN1 and CAPN2. Calpain modulates by proteolytic cleavage many cellular substrates and its activity is often deregulated in cancer cells, therefore calpain inhibition has been proposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5936d40d4fa41570e96f24eabddc7bc0
https://doi.org/10.1080/15384101.2015.1121325
https://doi.org/10.1080/15384101.2015.1121325
Publikováno v:
Molecular and cellular biology. 37(16)
Recently, autophagy has emerged as a critical process in the control of T-cell homeostasis. Given the pivotal role of NF-kappaB in the signaling events of T cells, we have analyzed and unveiled a conserved NF-kappaB binding site in the promoter of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835bed96beb09db647fa39d436c9238e
https://pubmed.ncbi.nlm.nih.gov/19289499
https://pubmed.ncbi.nlm.nih.gov/19289499
Autor:
Michael P. Myers, Elena Marcassa, Gianluca Triolo, Eeva-Liisa Eskelinen, Tahira Anwar, Claudio Schneider, Marzia Raimondi, Francesca Demarchi
Publikováno v:
BIOLOGY OPEN
Biology Open, Vol 6, Iss 5, Pp 551-562 (2017)
Biology Open
Biology Open, Vol 6, Iss 5, Pp 551-562 (2017)
Biology Open
CAPNS1 is essential for stability and function of the ubiquitous calcium-dependent proteases micro- and milli-calpain. Upon inhibition of the endoplasmic reticulum Ca2+ ATPase by 100 nM thapsigargin, both micro-calpain and autophagy are activated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df17d12b734a14eeb07d0043ca5bb3ab
http://livrepository.liverpool.ac.uk/3007884/1/biolopen-6-022806.pdf
http://livrepository.liverpool.ac.uk/3007884/1/biolopen-6-022806.pdf
Publikováno v:
Molecular and Cellular Biology. 29:2594-2608
Recently, autophagy has emerged as a critical process in the control of T-cell homeostasis. Given the pivotal role of NF-κB in the signaling events of T cells, we have analyzed and unveiled a conserved NF-κB binding site in the promoter of the muri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b3f93d4ce241219addb2eca8150f015
https://doi.org/10.1128/mcb.01396-08
https://doi.org/10.1128/mcb.01396-08
Autor:
Carmela Foti, Harish Potu, Alessandra Fontanini, Francesca Demarchi, Enrico Crivellato, Claudio Brancolini, Paolo Bernardi, Roberta Maestro
Publikováno v:
Journal of Biological Chemistry. 284:8369-8381
Inhibitors of the ubiquitin-proteasome system (UPSIs) promote apoptosis of cancer cells and show encouraging anti-tumor activities in vivo. In this study, we evaluated the death activities of two different UPSIs: bortezomib and the isopeptidase inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::766b32cc5e4654659aa0e20fcb43d34f
https://doi.org/10.1074/jbc.m806113200
https://doi.org/10.1074/jbc.m806113200