Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Francesca Del Bene"'
Autor:
Tae Eun Yang, Francesca Del Bene, Silvia Maria Lavezzi, Laura Iavarone, Jianping Zhang, Joseph Kim, Breanne Gjurich, Catherine Kessler
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 10, Pp 1722-1733 (2024)
Abstract The purpose of the analysis was to evaluate if 10 mg naloxone, administered intramuscularly, could reverse or prevent opioid‐induced respiratory depression (OIRD), including OIRD associated with the administration of lethal doses of high
Externí odkaz:
https://doaj.org/article/6ec5dd1f556e43ccbdc4e82c89924c8a
Autor:
Laura Oggianu, Beatrice Garrone, Francesco Fiorentini, Francesca Del Bene, Maria Teresa Rosignoli, Francesco Paolo Di Giorgio, Rafal Marian Kaminski
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 4, Pp 606-617 (2023)
Abstract A pharmacokinetic/pharmacodynamic (PK/PD) model was developed to describe the time course of writhings after intraperitoneal injection of acetic acid in mice. The model was applied to investigate the antinociceptive effect of trazodone and g
Externí odkaz:
https://doaj.org/article/ef97ad29d187425e8e3978539ad3e286
Autor:
Silvia Consalvi, Chiara Mozzetta, Paolo Bettica, Massimiliano Germani, Francesco Fiorentini, Francesca Del Bene, Maurizio Rocchetti, Flavio Leoni, Valmen Monzani, Paolo Mascagni, Pier Lorenzo Puri, Valentina Saccone
Publikováno v:
Molecular Medicine, Vol 19, Iss 1, Pp 79-87 (2013)
Abstract Previous work has established the existence of dystrophin-nitric oxide (NO) signaling to histone deacetylases (HDACs) that is deregulated in dystrophic muscles. As such, pharmacological interventions that target HDACs (that is, HDAC inhibito
Externí odkaz:
https://doaj.org/article/228636ca172f4dd983eb3ef54f6caf4d
Autor:
Laura Oggianu, Beatrice Garrone, Francesco Fiorentini, Francesca Del Bene, Maria Teresa Rosignoli, Francesco Paolo Di Giorgio, Rafal Marian Kaminski
Publikováno v:
Clinical and Translational Science. 16:606-617
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::924b2a2b38e8215a4fcfdc01d97175c5
https://doi.org/10.1111/cts.13472
https://doi.org/10.1111/cts.13472
Autor:
Robert Doornbos, Francesco Fiorentini, Tiziana Adage, Michael R. Bartley, Andreas J. Kungl, Christina Zankl, Francesca Del Bene
Publikováno v:
Cytokine. 76:433-441
Rationale Neutrophils play a fundamental role in a number of chronic lung diseases. Among the mediators of their recruitment to the lung, CXCL8 (IL-8) is considered to be one of the major players. CXCL8 exerts its chemotactic activity by binding to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60032653a4b2587125c36b94be1940bf
https://doi.org/10.1016/j.cyto.2015.08.006
https://doi.org/10.1016/j.cyto.2015.08.006
Autor:
Francesca Del Bene, Enrico Pesenti, Italo Poggesi, Maurizio Rocchetti, Massimiliano Germani, Paolo Magni, Giuseppe De Nicolao
Publikováno v:
Cancer chemotherapy and pharmacology. 71(5)
Pharmacokinetic–pharmacodynamic (PK–PD) models able to predict the action of anticancer compounds in tumor xenografts have an important impact on drug development. In case of anti-angiogenic compounds, many of the available models show difficulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a5454bce4cc2c14e9cdfe5896b1743
https://pubmed.ncbi.nlm.nih.gov/23430120
https://pubmed.ncbi.nlm.nih.gov/23430120
Publikováno v:
Computer methods and programs in biomedicine. 110(2)
Effective communication of PK/PD principles and results in a biomedical research environment remains a significant challenge which can result in lack of buy-in and engagement from scientists outside the modeling and simulation communities. In our vie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9968e1d5801821b818ca2f0d20884ff1
https://pubmed.ncbi.nlm.nih.gov/23182621
https://pubmed.ncbi.nlm.nih.gov/23182621
Autor:
Tiziana Adage, Christina Zankl, Francesco Fiorentini, Robert Doornbos, Francesca Del Bene, Andreas J. Kungl, Angelika Falsone
Publikováno v:
C31. REGULATION OF LUNG INFLAMMATION.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::469c48ab5f2c7eda44a049858318b3a2
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a4172
https://doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a4172
Autor:
Massimiliano Germani, Maurizio Rocchetti, Giuseppe De Nicolao, Paolo Magni, Dario Ballinari, Claudia Ernestina Re, Francesca Del Bene
Publikováno v:
Cancer chemotherapy and pharmacology. 63(5)
The use of in vitro screening tests for characterizing the activity of anticancer agents is a standard practice in oncology research and development. In these studies, human A2780 ovarian carcinoma cells cultured in plates are exposed to different co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f51bf799e1d86d99fa1c223f78c95e
https://pubmed.ncbi.nlm.nih.gov/18663447
https://pubmed.ncbi.nlm.nih.gov/18663447
Autor:
Chiara Mozzetta, Pier Lorenzo Puri, Flavio Leoni, Paolo Bettica, Silvia Consalvi, Francesco Fiorentini, Valentina Saccone, Maurizio Rocchetti, Francesca Del Bene, Paolo Mascagni, Massimiliano Germani, Valmen Monzani
Publikováno v:
Molecular Medicine; Vol 19
Previous work has established the existence of dystrophin-nitric oxide (NO) signaling to histone deacetylases (HDACs) that is deregulated in dystrophic muscles. As such, pharmacological interventions that target HDACs (that is, HDAC inhibitors) are o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2332f6b3c8ca879e2d191f0766503d73