Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Francesca D'addio"'
Autor:
Francesca D’Addio, Emma Assi, Anna Maestroni, Giada Rossi, Vera Usuelli, Adriana Petrazzuolo, Marta Nardini, Cristian Loretelli, Moufida Ben Nasr, Paolo Fiorina
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Pancreatic beta cells replenishment is considered the next therapeutic option for type 1 diabetes; while stimulating endogenous beta cells proliferation is the “holy grail” for those patients with exhausted beta cell mass. Here we are demonstrati
Externí odkaz:
https://doaj.org/article/3c19f5f129a14d3dadfdbfbfd1eeb6c7
Autor:
Maria Elena Lunati, Vincenzo Cimino, Davide Bernasconi, Alessandra Gandolfi, Paola Silvia Morpurgo, Camilla Tinari, Elisa Lazzaroni, Laura Baruffaldi, Milena Muratori, Laura Montefusco, Ida Pastore, Antonio Rossi, Ivano Giuseppe Franzetti, Fabrizio Muratori, Roberto Manfrini, Olga Eugenia Disoteo, Rosa Terranova, Paolo Desenzani, Angela Girelli, Renata Ghelardi, Francesca D’Addio, Moufida Ben Nasr, Cesare Berra, Franco Folli, Loredana Bucciarelli, Paolo Fiorina
Publikováno v:
Pharmacological Research, Vol 199, Iss , Pp 107040- (2024)
Dapagliflozin, a sodium-glucose co-transporter-2 inhibitor and semaglutide, a glucagon-like peptide 1 receptor agonist, have both demonstrated efficacy in glycemic control, reducing blood pressure, body weight, risk of renal and heart failure in type
Externí odkaz:
https://doaj.org/article/896fc8acef4049c186f0bd9af04fa581
Autor:
Cristian Loretelli, Ida Pastore, Maria Elena Lunati, Ahmed Abdelsalam, Vera Usuelli, Emma Assi, Emma Fiorina, Lara Loreggian, Hari Baskar Balasubramanian, Yanan Xie, Jun Yang, Basset El Essawy, Laura Montefusco, Francesca D’Addio, Moufida Ben Nasr, Paolo Fiorina
Publikováno v:
Pharmacological Research, Vol 190, Iss , Pp 106709- (2023)
Purpose of review: The purine nucleotide adenosine triphosphate (ATP) is released into extracellular spaces as extracellular ATP (eATP) as a consequence of cell injury or death and activates the purinergic receptors. Once released, eATP may facilitat
Externí odkaz:
https://doaj.org/article/5c2281d1b2b142519e43165a1710f8a3
Autor:
Adriana Petrazzuolo, Gianmarco Sabiu, Emma Assi, Anna Maestroni, Ida Pastore, Maria Elena Lunati, Laura Montefusco, Cristian Loretelli, Giada Rossi, Moufida Ben Nasr, Vera Usuelli, Yanan Xie, Hari Baskar Balasubramanian, Monica Zocchi, Basset El Essawy, Jun Yang, Francesca D’Addio, Paolo Fiorina
Publikováno v:
Pharmacological Research, Vol 190, Iss , Pp 106710- (2023)
Diabetic kidney disease (DKD) is the first cause of end-stage kidney disease in patients with diabetes and its prevalence is increasing worldwide. It encompasses histological alterations that mainly affect the glomerular filtration unit, which includ
Externí odkaz:
https://doaj.org/article/f4d913eb8c7b477ba0c24bf7919d6299
Autor:
Francesca D’Addio, Anna Maestroni, Emma Assi, Moufida Ben Nasr, Giovanni Amabile, Vera Usuelli, Cristian Loretelli, Federico Bertuzzi, Barbara Antonioli, Francesco Cardarelli, Basset El Essawy, Anna Solini, Ivan C. Gerling, Cristina Bianchi, Gabriella Becchi, Serena Mazzucchelli, Domenico Corradi, Gian Paolo Fadini, Diego Foschi, James F. Markmann, Emanuela Orsi, Jan Škrha, Maria Gabriella Camboni, Reza Abdi, A. M. James Shapiro, Franco Folli, Johnny Ludvigsson, Stefano Del Prato, Gianvincenzo Zuccotti, Paolo Fiorina
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
In this new study the Authors demonstrated that the IGFBP3/TMEM219 pathway is a physiological regulator of pancreatic beta cell homeostasis and it is dysregulated in diabetes. IGFBP3/TMEM219 targeting may therefore serve as a therapeutic option in di
Externí odkaz:
https://doaj.org/article/691fd79ad7294c7890d97254a673270c
Autor:
Elisa Lazzaroni, Maria Elena Lunati, Laura Montefusco, Ida Pastore, Enrica Chebat, Vincenzo Cimino, Paola Silvia Morpurgo, Milena Muratori, Laura Plebani, Andrea Bolla, Antonio Rossi, Luciana Vallone, Alessandra Gandolfi, Camilla Tinari, Francesca D’Addio, Moufida Ben Nasr, Cristian Loretelli, Cristiana Scaranna, Rosalia Bellante, Roberto Manfrini, Fabrizio Muratori, Ivano Franzetti, Emanuela Orsi, Carmine Gazzaruso, Renata Ghelardi, Paolo Desenzani, Stefano Genovese, Angela Girelli, Franco Folli, Cesare Berra, Paolo Fiorina
Publikováno v:
Pharmacological Research, Vol 183, Iss , Pp 106374- (2022)
Dapagliflozin has been demonstrated to improve glycemic control, blood pressure, and body weight in type 2 diabetes mellitus (T2D); indeed, it can also reduce the risk of progression to renal failure, of hospitalization for heart failure and of cardi
Externí odkaz:
https://doaj.org/article/bebdf59a7df04d4580f983cb409b28c8
Autor:
Cristian Loretelli, Ahmed Abdelsalam, Francesca D’Addio, Moufida Ben Nasr, Emma Assi, Vera Usuelli, Anna Maestroni, Andy Joe Seelam, Elio Ippolito, Stefania Di Maggio, Lara Loreggian, Dejan Radovanovic, Claudia Vanetti, Jun Yang, Basset El Essawy, Antonio Rossi, Ida Pastore, Laura Montefusco, Maria Elena Lunati, Andrea M. Bolla, Mara Biasin, Spinello Antinori, Pierachille Santus, Agostino Riva, Gian Vincenzo Zuccotti, Massimo Galli, Stefano Rusconi, Paolo Fiorina
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
A substantial proportion of patients who have recovered from coronavirus disease-2019 (COVID-19) experience COVID-19–related symptoms even months after hospital discharge. We extensively immunologically characterized patients who recovered from COV
Externí odkaz:
https://doaj.org/article/d677986fcd484bfc91c312a6c5663b31
Autor:
Ida Pastore, Emma Assi, Moufida Ben Nasr, Andrea Mario Bolla, Anna Maestroni, Vera Usuelli, Cristian Loretelli, Andy Joe Seelam, Ahmed Abdelsalam, Gian Vincenzo Zuccotti, Francesca D’Addio, Paolo Fiorina
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Despite the increasing knowledge of pathophysiological mechanisms underlying the onset of type 1 diabetes (T1D), the quest for therapeutic options capable of delaying/reverting the diseases is still ongoing. Among all strategies currently tested in T
Externí odkaz:
https://doaj.org/article/09f67fa8c46c4196838e948fc508bc7c
Autor:
Irene Cetin, Emma Assi, Francesca D'Addio, Chiara Mandò, Anna Maestroni, Cristian Loretelli, Moufida Ben Nasr, Vera Usuelli, Ahmed Abdelsalam, Andy Joe Seelam, Ida Pastore, Cinzia Magagnotti, Reza Abdi, Basset El Essawy, Franco Folli, Domenico Corradi, Gianvincenzo Zuccotti, Paolo Fiorina
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 2 (2020)
Introduction Gestational diabetes mellitus (GDM) is the most frequent metabolic complication during pregnancy and is associated with development of short-term and long-term complications for newborns, with large-for-gestational-age (LGA) being partic
Externí odkaz:
https://doaj.org/article/57b6bc61b0354fbdbf7c611824966d41
Autor:
Moufida Ben Nasr, Francesca D’Addio, Amir Mohammad Malvandi, Silvia Faravelli, Eduardo Castillo-Leon, Vera Usuelli, Francesca Rocchio, Teresa Letizia, Abdel Basset El Essawy, Emma Assi, Chiara Mameli, Elisa Giani, Maddalena Macedoni, Anna Maestroni, Alice Dassano, Cristian Loretelli, Moira Paroni, Giuseppe Cannalire, Giacomo Biasucci, Marco Sala, Alessandra Biffi, Gian Vincenzo Zuccotti, Paolo Fiorina
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Hematopoietic stem and progenitor cells (HSPCs) are multipotent stem cells that have been harnessed as a curative therapy for patients with hematological malignancies. Notably, the discovery that HSPCs are endowed with immunoregulatory properties sug
Externí odkaz:
https://doaj.org/article/0b374b2530d94747ad3cf87276752547