Zobrazeno 1 - 10 of 37 pro vyhledávání: '"Francesca D'Acunzo"'
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Akademický článek
Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives
Autor: Francesco Fiorentino, Marta De Angelis, Martina Menna, Annarita Rovere, Anna Maria Caccuri, Francesca D’Acunzo, Anna Teresa Palamara, Lucia Nencioni, Dante Rotili, Antonello Mai
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 2128-2138 (2021)
Influenza viruses represent a major threat to human health and are responsible for seasonal epidemics, along with pandemics. Currently, few therapeutic options are available, with most drugs being at risk of the insurgence of resistant strains. Hence
Externí odkaz: https://doaj.org/article/ecff4c5a42794137b561ff775ca35eb0
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2
Akademický článek
Ready-to-eat vegetables production with low-level water chlorination: an evaluation of water quality and of its impact on end products
Autor: Francesca D'Acunzo, Angela Del Cimmuto, Lucia Marinelli, Caterina Aurigemma, Maria De Giusti
Publikováno v: Annali dell'Istituto Superiore di Sanità, Vol 48, Iss 2, Pp 151-160 (2012)
INTRODUCTION: We evaluated the microbiological impact of low-level chlorination (1 ppm free chlorine) on the production of ready-to-eat (RTE) vegetables by monitoring the microbiological quality of irrigation and processing water in two production pl
Externí odkaz: https://doaj.org/article/30324c9649514299b179e76b8ae00f39
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3
First-in-Class Selective Inhibitors of the Lysine Acetyltransferase KAT8
Autor: Francesco Fiorentino, Sara Sementilli, Martina Menna, Federica Turrisi, Stefano Tomassi, Francesca Romana Pellegrini, Angela Iuzzolino, Francesca D’Acunzo, Alessandra Feoli, Hannah Wapenaar, Sophie Taraglio, Caterina Fraschetti, Donatella Del Bufalo, Gianluca Sbardella, Frank J. Dekker, Alessandro Paiardini, Daniela Trisciuoglio, Antonello Mai, Dante Rotili
Publikováno v: Journal of Medicinal Chemistry. 66:6591-6616
KAT8 is a lysine acetyltransferase primarily catalyzing the acetylation of Lys16 of histone H4 (H4K16). KAT8 dysregulation is linked to the development and metastatization of many cancer types, including non-small cell lung cancer (NSCLC) and acute m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea342da8b3200831d0d340ba9279a35e
https://doi.org/10.1021/acs.jmedchem.2c01937
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4
Influence of Nanoaggregation Routes on the Structure and Thermal Behavior of Multiple-Stimuli-Responsive Micelles from Block Copolymers of Oligo(ethylene glycol) Methacrylate and the Weak Acid [2-(Hydroxyimino)aldehyde]butyl Methacrylate
Autor: Irene, Antignano, Francesca, D'Acunzo, Davide, Arena, Stefano, Casciardi, Alessandra, Del Giudice, Francesca, Gentile, Maria, Pelosi, Giancarlo, Masci, Patrizia, Gentili
Publikováno v: Langmuir : the ACS journal of surfaces and colloids. 38(46)
In this work, we compare nanoaggregation driven by pH-induced micellization (PIM) and by the standard solvent displacement (SD) method on a series of pH-, light-, and thermosensitive amphiphilic block copolymers. Specifically, we investigate poly(HIA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f31bded3ee43e481b1e72da74c3a093d
https://pubmed.ncbi.nlm.nih.gov/36346681
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5
Sirtuin modulators: past, present, and future perspectives
Autor: Francesco Fiorentino, Nicola Mautone, Martina Menna, Francesca D'Acunzo, Antonello Mai, Dante Rotili
Publikováno v: Future Med Chem
Sirtuins are NAD+-dependent protein lysine deacylase and mono-ADP ribosylases present in both prokaryotes and eukaryotes. The sirtuin family comprises seven isoforms in mammals, each possessing different subcellular localization and biological functi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::099270437ae0c19f202a8e6adf043d4c
http://hdl.handle.net/11573/1638052
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6
Unusually chemoselective photocyclization of 2-(hydroxyimino)aldehydes to cyclobutanol oximes. synthetic, stereochemical, and mechanistic aspects
Autor: Antonio Di Sabato, Francesca D’Acunzo, Dario Filippini, Fabrizio Vetica, Antonio Brasiello, Davide Corinti, Enrico Bodo, Cinzia Michenzi, Edoardo Panzetta, Patrizia Gentili
Photocyclization of carbonyl compounds (known as the Norrish-Yang reaction) to yield cyclobutanols is, in general, accompanied by fragmentation reactions. The latter are predominant in the case of aldehydes so that secondary cyclobutanols are not con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee6b0894e8f6c32cf1f50248516cd7b
https://hdl.handle.net/11573/1656147
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7
Anti-influenza A virus activity and structure-activity relationship of a series of nitrobenzoxadiazole derivatives
Autor: Francesca D'Acunzo, Anna Maria Caccuri, Dante Rotili, Annarita Rovere, Martina Menna, Lucia Nencioni, Marta De Angelis, Anna Teresa Palamara, Francesco Fiorentino, Antonello Mai
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 2128-2138 (2021)
Influenza viruses represent a major threat to human health and are responsible for seasonal epidemics, along with pandemics. Currently, few therapeutic options are available, with most drugs being at risk of the insurgence of resistant strains. Hence
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff87b275ed39e5db8f4be774cae288f
https://pubmed.ncbi.nlm.nih.gov/34583607
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8
Click-Connected 2-(Hydroxyimino)aldehydes for the Design of UV-Responsive Functional Molecules
Autor: Francesca D'Acunzo, L. Mancini, Antonella Dalla Cort, Linda Carbonaro, Patrizia Gentili, Francesca Leonelli, Antonio Di Sabato, Dario Filippini
Publikováno v: European journal of organic chemistry (Online) 2021 (2021): 289–294. doi:10.1002/ejoc.202001303
info:cnr-pdr/source/autori:D'Acunzo F.; Carbonaro L.; Cort A.D.; Di Sabato A.; Filippini D.; Leonelli F.; Mancini L.; Gentili P./titolo:Click-Connected 2-(Hydroxyimino)aldehydes for the Design of UV-Responsive Functional Molecules/doi:10.1002%2Fejoc.202001303/rivista:European journal of organic chemistry (Online)/anno:2021/pagina_da:289/pagina_a:294/intervallo_pagine:289–294/volume:2021
Click chemistry is used to functionalize simple lipophilic and water-soluble molecules, a complex PEGylated phospholipid (DSPE-PEG2000), and two benzylic substrates with the 2-(hydroxyimino)aldehyde (HIA) group. To this end, two terminal alkynes bear
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f54f9ded43fa41abb5bea0f03ee1e3
https://publications.cnr.it/doc/443302
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10
2-(Hydroxyimino)aldehydes: Photo- and Physicochemical Properties of a Versatile Functional Group for Monomer Design
Autor: Francesca D'Acunzo, Martina Nardi, Paolo Cambise, Alessandro Pinna, Marco D'Abramo, Emanuele Ussia, Irene Antignano, Patrizia Gentili
Publikováno v: Chemistry-A European Journal 24 (2018): 7683–7694. doi:10.1002/chem.201800059
info:cnr-pdr/source/autori:Gentili P. (a,b); Nardi M. (a,b); Antignano I. (a); Cambise P. (a); D'Abramo M. (a); D'Acunzo F. (b); Pinna A. (a); Ussia E. (a)/titolo:2-(Hydroxyimino)aldehydes: Photo-and Physicochemical Properties of a Versatile Functional Group for Monomer Design/doi:10.1002%2Fchem.201800059/rivista:Chemistry-A European Journal/anno:2018/pagina_da:7683/pagina_a:7694/intervallo_pagine:7683–7694/volume:24
In the context of our research on stimuli-responsive polymers bearing the 2-(hydroxyimino)aldehyde (HIA) group, we have explored the photochemical behavior and physicochemical properties of a number of HIAs. Interpretation of the experimental data is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b341075796461465d9366441af303949
https://doi.org/10.1002/chem.201800059
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