Výsledky vyhledávání - "Francesca Cutillo"

Akademický článek

In-vivo biological activity and glycosylation analysis of a biosimilar recombinant human follicle-stimulating hormone product (Bemfola) compared with its reference medicinal product (GONAL-f).

Autor: Renato Mastrangeli, Abhijeet Satwekar, Francesca Cutillo, Cinzia Ciampolillo, Wolf Palinsky, Salvatore Longobardi

Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0184139 (2017)

Recombinant human follicle-stimulating hormone (r-hFSH) is widely used in fertility treatment. Although biosimilar versions of r-hFSH (follitropin alfa) are currently on the market, given their structural complexity and manufacturing process, it is i

Externí odkaz: https://doaj.org/article/072e4a1d8e704d50b6fa00e57460eaa3

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Site-specific N- and O-glycosylation analysis of atacicept

Autor: Elena Dominguez Vega, Kathrin Stavenhagen, Horst Bierau, Rabah Gahoual, Wolf Palinsky, Agnes L. Hipgrave Ederveen, Angelo Palmese, Francesca Cutillo, Manfred Wuhrer

Publikováno v: mAbs, 11(6), 1053-1063. Taylor & Francis
mAbs
mAbs, 11(6), 1053-1063
Stavenhagen, K, Gahoual, R, Dominguez Vega, E, Palmese, A, Ederveen, A L H, Cutillo, F, Palinsky, W, Bierau, H & Wuhrer, M 2019, ' Site-specific N-and O-glycosylation analysis of atacicept ', mAbs, vol. 11, no. 6, pp. 1053-1063 . https://doi.org/10.1080/19420862.2019.1630218

The Fc-fusion protein atacicept is currently under clinical investigation for its biotherapeutic application in autoimmune diseases owing to its ability to bind the two cytokines B-Lymphocyte Stimulator (BLyS) and A PRoliferation-Inducing Ligand (APR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec398b44922155a047531398cd34f37b
https://research.vu.nl/en/publications/d14a8e17-ace3-4fbb-8e96-11885ce8bab6

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In-vivo biological activity and glycosylation analysis of a biosimilar recombinant human follicle-stimulating hormone product (Bemfola) compared with its reference medicinal product (GONAL-f)

Autor: Wolf Palinsky, Salvatore Longobardi, Abhijeet Satwekar, Renato Mastrangeli, Francesca Cutillo, Cinzia Ciampolillo

Publikováno v: PLoS ONE
PLoS ONE, Vol 12, Iss 9, p e0184139 (2017)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5013d5c0019169ca8644d162bc643e78
https://pubmed.ncbi.nlm.nih.gov/28880909

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Phenols and lignans fromChenopodium album

Autor: Francesca Cutillo, Lucio Previtera, Armando Zarrelli, Melania Gionti, Marina DellaGreca

Publikováno v: Phytochemical Analysis. 17:344-349

Cinnamic acid, 4-hydroxy-cinnamic acid, ferulic acid, methyl ferulate, sinapic acid, methyl 3-(4-hydroxy-3-methoxyphenyl)propanoate, 4-(1-hydroxyethyl)-2-methoxyphenol, vanillyl alcohol, 4-(hydroxymethyl)-2-methoxyphenol, 4-hydroxy-3-methoxybenzoic a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b93a72d64282aa168b48596d086922
https://doi.org/10.1002/pca.924

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Chenoalbicin, a Novel Cinnamic Acid Amide Alkaloid fromChenopodium album

Autor: Armando Zarrelli, Brigida D'Abrosca, Francesca Cutillo, Marina DellaGreca

Publikováno v: Chemistry & Biodiversity. 1:1579-1583

The roots of Chenopodium album were infused in MeOH, and the extract was partitioned between AcOEt and H2O. AcOEt-Soluble material was subjected to different silica-gel column chromatographies and then purified by reverse-phase HPLC to afford a new c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9140563d841d196a4e414c215c86d4b
https://doi.org/10.1002/cbdv.200490118

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Lignans and Neolignans from Brassica fruticulosa: Effects on Seed Germination and Plant Growth

Autor: Francesca Cutillo, Armando Zarrelli, Brigida D'Abrosca, and Antonio Fiorentino, Marina DellaGreca

Publikováno v: Journal of Agricultural and Food Chemistry. 51:6165-6172

Five lignans, five neolignans, two sesquilignans, and a dilignan were identified from a phytotoxic extract of Brassica fruticulosa L. Compounds 8, 9, 12, and 13 have been isolated for the first time. Structures were determined on the basis of their s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eed26bf901990235b4a0ffb32610eaa
https://doi.org/10.1021/jf034644c

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Analysis of native and APTS-labeled N-glycans by capillary electrophoresis/time-of-flight mass spectrometry

Autor: Svenja-Catharina Bunz, Christian Neusüß, Francesca Cutillo

Publikováno v: Analytical and bioanalytical chemistry. 405(25)

The glycosylation of proteins is of particular interest in biopharmaceutical applications. The detailed characterization of glycosylation based on the released carbohydrates is mandatory since the protein stability, folding, and efficacy are strongly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10140af28a2f36c61a09c9e2ad68c497
https://pubmed.ncbi.nlm.nih.gov/23912827

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Antioxidant and radical scavenging properties of Malva sylvestris

Autor: Marina, DellaGreca, Francesca, Cutillo, Brigida, D'Abrosca, Antonio, Fiorentino, Severina, Pacifico, Armando, Zarrelli

Publikováno v: Natural product communications. 4(7)

Antioxidant capacity of the aqueous extract of Malva sylvestris was measured by its ability to scavenge the DPPH and superoxide anion radicals and to induce the formation of a phosphomolybdenum complex. Analysis of the extract, carried out by differe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::62ef2cd160e8974ebdf6d1effb2d74dd
https://pubmed.ncbi.nlm.nih.gov/19731587

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Terpenoids and phenol derivatives from Malva silvestris

Autor: Francesca Cutillo, Marina DellaGreca, Antonio Fiorentino, Armando Zarrelli, Brigida D'Abrosca

A sesquiterpene and a tetrahydroxylated acyclic diterpene as well as two known monoterpenes, 6 C13nor-terpenes and 11 aromatic compounds were isolated from the water extract of Malva silvestris. The structures of the compounds were determined by spec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eacdb72ae1e560d378039dba7ab5397
http://hdl.handle.net/11591/191147

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C13 norisoprenoids from Brassica fruticulosa

Autor: Marina DellaGreca, Francesca Cutillo, Lucio Previtera, Armando Zarrelli

Publikováno v: Natural product research. 19(2)

Five C13 norisoprenoids, one of them glucosilated, have been isolated from the leaves of Brassica fruticulosa (Brassicaceae). The structure (3S,4R,7E,9S)-3,4,9-trihydroxy-5,7-megastigmadiene, has been assigned to the new compound. All the structures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4c5fc5fbe930174c0e413767dcc330
https://pubmed.ncbi.nlm.nih.gov/15715251

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